Zobrazeno 1 - 7
of 7
pro vyhledávání: '"L A Pittarelli"'
Autor:
Karl H. Nollstadt, M. A. Romancheck, Robert E. Schwartz, Kenneth E. Wilson, Vanmiddlesworth Frank L, Mervyn J. Turner, L. A. Pittarelli, Robert A. Fromtling, Dennis M. Schmatz
Publikováno v:
Proceedings of the National Academy of Sciences. 87:5950-5954
Pneumocystis carinii pneumonia is a major cause of death in AIDS patients in the United States. The presently available treatments have limited use due to a high incidence of adverse reactions. Therefore, there is an urgent need for a safer method fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1fd413622cdb5df7bf1339f2349743
https://doi.org/10.1073/pnas.87.15.5950
https://doi.org/10.1073/pnas.87.15.5950
Autor:
L A, Pittarelli, S L, Faris-Young
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 29(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f70050652086ed514389f5440b910995
https://pubmed.ncbi.nlm.nih.gov/10589882
https://pubmed.ncbi.nlm.nih.gov/10589882
Autor:
Jennifer W. Anderson, M A Powles, D C Graves, M Becker-Hapak, Paul A. Liberator, M Worley, Dennis M. Schmatz, L A Pittarelli
Publikováno v:
Journal of clinical microbiology. 30(11)
A repetitive genomic DNA clone (B12-2) that specifically hybridizes to Pneumocystis carinii DNA has been identified. No cross-hybridization to genomic DNA prepared from bacteria, other fungi, protozoa, or mammals was observed. Clone B12-2 is multiply
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6bb00be2c8215de932883a1d177862
https://pubmed.ncbi.nlm.nih.gov/1452667
https://pubmed.ncbi.nlm.nih.gov/1452667
Autor:
M A Powles, L A Pittarelli, Robert A. Zambias, Milton L. Hammond, D C McFadden, James M. Balkovec, Jennifer W. Anderson, Dennis M. Schmatz, Paul A. Liberator
Water-soluble lipopeptide L-693,989 was evaluated for its antipneumocystis activity in rats. Rats from colonies with latent Pneumocystis carinii infections were immunosuppressed with dexamethasone for 6 weeks to facilitate the development of acute P.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08595207bc1539e533e641671d880b43
https://europepmc.org/articles/PMC192216/
https://europepmc.org/articles/PMC192216/
Animal models for Pneumocystis carinii, for the most part, have been limited to immunosuppressed rats and ferrets, while a dependable mouse model has been more difficult to develop. A P. carinii mouse model has now been established with several strai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc41b4a241428cae0966382acb66810
https://europepmc.org/articles/PMC257010/
https://europepmc.org/articles/PMC257010/
Publikováno v:
The Journal of protozoology. 38(6)
A mouse model for Pneumocystis carinii has now been established in several strains of mice: C3Heb/FeJ, C3HeN, Balb/c, DBA/2N and athymic. In lieu of using invasive methods for initiating P. carinii infections, mice infected with P. carinii (seed mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2defc8f83f66f604ce0c9aff4c547b56
https://pubmed.ncbi.nlm.nih.gov/1818134
https://pubmed.ncbi.nlm.nih.gov/1818134
Publikováno v:
The Journal of protozoology. 38(6)
Two different classes of 1,3-beta-glucan synthesis inhibitors, the echinocandins and papulacandins, have anti-Pneumocystis activity in an immunosuppressed rat model for acute P. carinii pneumonia (PCP). This activity combined with potent anti-Candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a904510f8a10ceb20675b62b9a80412f
https://pubmed.ncbi.nlm.nih.gov/1818147
https://pubmed.ncbi.nlm.nih.gov/1818147