Zobrazeno 1 - 2
of 2
pro vyhledávání: '"L A Kopta"'
Autor:
T J Poel, Richard C. Thomas, K B Rank, R A Morge, S W Newport, Y Yagi, C Biles, T J Dueweke, D. L. Romero, R A Olmsted, L A Kopta, S K Sharma, D E Slade, W. G. Tarpley, S M Poppe
Publikováno v:
Journal of Virology. 70:3698-3705
The (alkylamino)piperidine bis(heteroaryl)piperizines (AAP-BHAPs) are a new class of human immunodeficiency virus type 1 (HIV-1)-specific inhibitors which were identified by targeted screening of recombinant reverse transcriptase (RT) enzymes carryin
Autor:
Naisheng Fan, S K Sharma, S M Poppe, Richard C. Thomas, David B. Evans, K B Rank, L A Kopta, D E Slade, W. G. Tarpley, R A Olmsted
Publikováno v:
Biochemistry. 35:9737-9745
Selection of the IIIB strain of human immunodeficiency virus type (HIV-1) resistant to the (alkylamino)piperidine-bis(heteroaryl)piperazine (AAP-BHAP) U-104489 results in substitution of a glycine to glutamate at residue 190 (G190E) of reverse transc