Zobrazeno 1 - 10
of 16
pro vyhledávání: '"L A Ivanushko"'
Autor:
T. A. Kuznetsova, T. A. Smolina, L. A. Ivanushko, E. V. Persiyanova, A. S. Silchenko, N. N. Besednova
Publikováno v:
Антибиотики и Химиотерапия, Vol 68, Iss 3-4, Pp 25-29 (2023)
Objectives. No sulfated polysaccharides (fucoidans) has been declared as the pharmaceutical substances, adjuvants, etc., which is associated with the problems of obtaining the structurally characterized and homogeneous samples or their oligomeric fra
Externí odkaz:
https://doaj.org/article/9ba2d55e168c453bb05cc74109a5355e
Autor:
T. A. Kuznetsova, T. P. Smolina, E. V. Persiyanova, L. A. Ivanushko, A. S. Silchenko, S. P. Ermakova, N. N. Besednova
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 22, Iss 3, Pp 308-317 (2022)
The use of sulfated polysaccharides (fucoidans) as active pharmaceutical ingredients or adjuvants poses the challenge of obtaining structurally characterised and homogeneous samples or their oligomeric fractions maintaining high biological activity.
Externí odkaz:
https://doaj.org/article/719ed4b54cac454591a5e6e2832fb5c9
Autor:
T. A. Kuznetsova, E. V. Persiyanova, L. A. Ivanushko, T. P. Smolina, A. K. Gazha, M. S. Kokulin, N. N. Besednova
Publikováno v:
Антибиотики и Химиотерапия, Vol 66, Iss 5-6, Pp 17-22 (2021)
Aim. To assess the mechanisms of immunoadjuvant activity of marine bacteria exopolysaccharides (PS) in normal and immunosuppressive conditions in vivo. Material and methods. Experimental studies were carried out on male ВALB/c mice, immunized with c
Externí odkaz:
https://doaj.org/article/3dde3914c93146279a4e0a7269abfd15
Autor:
T. A. Kuznetsova, N. N. Besednova, T. S. Zaporozhets, T. P. Smolina, A. K. Gazha, L. A. Ivanushko
Publikováno v:
Антибиотики и Химиотерапия, Vol 58, Iss 11-12, Pp 8-12 (2020)
The immunomodulatory activity of peptide drugs: i.e. tinrostim (dosage form) prepared of squid optical ganglia and pharmacopoeia thymalin was studied. Tinrostim showed a stimulating effect on the humoral and cellular immune responses when administere
Externí odkaz:
https://doaj.org/article/024555c232f84bc794a6163271a3eb84
Autor:
T. P. Smolina, T. A. Kuznetsova, L. A. Ivanushko, A. K. Gazha, A. S. Silchenko, N. N. Besednova
Publikováno v:
Антибиотики и Химиотерапия, Vol 64, Iss 9-10, Pp 3-7 (2020)
The article studies the effect of sulfated polysaccharide extracted from brown algae Fucus evanescens(fucoidan) and the product of its enzymatic transformation on human NK and NKT cells. Significant phenotypic changes in NK and NKT cells were recorde
Externí odkaz:
https://doaj.org/article/3789fe4a531c4cb4a8747eef84ebe1e2
Autor:
L. A. Ivanushko, T. F. Solovyeva, T. S. Zaporozhets, P. A. Lukyanov, V. I. Gorbach, N. N. Besednova
Publikováno v:
Медицинская иммунология, Vol 9, Iss 4-5, Pp 397-404 (2014)
Abstract. Comparative study was carried out, aiming to assess immunostimulatory properties of high-molecular chitosan (Ch-HM) and its derivatives, i.e., low molecular weight chitosan (Ch-LM), N-3-hydroxymyristoyl (Ch-LM) at a low acylation ratio, N-3
Externí odkaz:
https://doaj.org/article/36f42f2212614ca08e4f91868d8e5cee
Autor:
T. A. Kuznetsova, Elena V. Persiyanova, L A Ivanushko, A L Shutikova, Svetlana P. Ermakova, N. N. Besednova, M. Yu. Khotimchenko
Publikováno v:
Biomeditsinskaia khimiia. 63(6)
The use of sulfated polysaccharides from brown seaweed Fucus evanescens as adjuvants (native fucoidan in combination with polyphenols, fucoidan without polyphenols, a product of enzymatic hydrolysis of fucoidan) stimulated the formation of specific a
Publikováno v:
Bulletin of experimental biology and medicine. 156(3)
The effects of triterpene glycosides (saponins) extracted from Saponaria officinalis L. radices, on the cellular and humoral innate immunity factors were studied. Saponins stimulated the phagocytic, bactericidal, and adhesion activities of polymorpho
Autor:
L N, Fedianina, V V, Potapova, L A, Ivanushko, N N, Besednova, L N, Epshteĭn, I A, Orlovskaia, B G, Blinov
Publikováno v:
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 49(4)
Biological activity of low molecular DNA isolated from salmon milt was studied. When administered subcutaneously to mice with with acute experimental radiation disease in a course dose of 10 mg/kg, it showed a therapeutic effect, stimulated hemopoies
Autor:
T P, Smolina, R P, Gorshkova, E L, Nazarenko, L A, Ivanushko, T S, Zaporozhets, N N, Besednova
Publikováno v:
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 47(1)
Immune system modulating activity of exoglycane isolated from culture media of Vibrio alginolyticus (strain 945-80) was investigated. The substance demonstrated stimulating activity on the humoral and cell immune system, potentiated phagocyte activit