Zobrazeno 1 - 10
of 386
pro vyhledávání: '"L A Doyle"'
Autor:
AuraLea Fain, Ayden McCarthy, Bradley C. Nindl, Joel T. Fuller, Jodie A. Wills, Tim L. A. Doyle
Publikováno v:
Sensors, Vol 24, Iss 5, p 1675 (2024)
The ability to estimate lower-extremity mechanics in real-world scenarios may untether biomechanics research from a laboratory environment. This is particularly important for military populations where outdoor ruck marches over variable terrain and t
Externí odkaz:
https://doaj.org/article/1454a5ad08c744a7a3bb7ee43e93cd07
Autor:
Matthew B. Bird, Kristen J. Koltun, Qi Mi, Mita Lovalekar, Brian J. Martin, Tim L. A. Doyle, Bradley C. Nindl
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Recently, commercial grade technologies have provided black box algorithms potentially relating to musculoskeletal injury (MSKI) risk and functional movement deficits, in which may add value to a high-performance model. Thus, the purpose of this manu
Externí odkaz:
https://doaj.org/article/35ca4cf0f64b45eaa366ebcbc42293d1
Autor:
Matthew B. Bird, Qi Mi, Kristen J. Koltun, Mita Lovalekar, Brian J. Martin, AuraLea Fain, Angelique Bannister, Angelito Vera Cruz, Tim L. A. Doyle, Bradley C. Nindl
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Musculoskeletal injuries (MSKI) are a significant burden on the military healthcare system. Movement strategies, genetics, and fitness level have been identified as potential contributors to MSKI risk. Screening measures associated with MSKI risk are
Externí odkaz:
https://doaj.org/article/db8a9a0d1ce04b0eb7b2189c85d253be
Autor:
M. D. Fahlberg, R. V. Blair, L. A. Doyle-Meyers, C. C. Midkiff, G. Zenere, K. E. Russell-Lodrigue, C. J. Monjure, E. H. Haupt, T. P. Penney, G. Lehmicke, B. M. Threeton, N. Golden, P. K. Datta, C. J. Roy, R. P. Bohm, N. J. Maness, T. Fischer, J. Rappaport, M. Vaccari
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Here, Fahlberg et al. describe the cellular immune response during acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates. The study identifies associations of monocytes and macrophage subtypes in lungs with disease outcom
Externí odkaz:
https://doaj.org/article/ed379c7b9e49434d81343f5e0569e2da
Autor:
Yan Xing, Nancy U. Lin, Matthew A. Maurer, Huiqin Chen, Armeen Mahvash, Aysegul Sahin, Argun Akcakanat, Yisheng Li, Vandana Abramson, Jennifer Litton, Mariana Chavez-MacGregor, Vicente Valero, Sarina A. Piha-Paul, David Hong, Kim-Anh Do, Emily Tarco, Dianna Riall, Agda Karina Eterovic, Gerburg M. Wulf, Lewis C. Cantley, Gordon B. Mills, L. Austin Doyle, Eric Winer, Gabriel N. Hortobagyi, Ana Maria Gonzalez-Angulo, Funda Meric-Bernstam
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-12 (2019)
Abstract Background The PI3K/AKT pathway is activated through PIK3CA or AKT1 mutations and PTEN loss in breast cancer. We conducted a phase II trial with an allosteric AKT inhibitor MK-2206 in patients with advanced breast cancer who had tumors with
Externí odkaz:
https://doaj.org/article/3eaaeb80b88d4c81acd24e596bc7212d
Autor:
Elizabeth K. Lee, Zhenying Tan-Wasielewski, Carol Aghajanian, Robert L. Coleman, Jennifer Curtis, Michelle S. Hirsch, Ursula A. Matulonis, Lewis C. Cantley, Gordon B. Mills, L. Austin Doyle, Joyce F. Liu
Publikováno v:
Gynecologic Oncology Reports, Vol 32, Iss , Pp - (2020)
Platinum-resistant, recurrent, high grade epithelial ovarian carcinoma remains challenging to treat. Chemotherapy produces limited responses with modest survival benefits in the treatment of recurrent disease. In this context, targeted therapies may
Externí odkaz:
https://doaj.org/article/24282615b07b4f289616a02c35432ae1
Autor:
Hagop M. Kantarjian, Elihu H. Estey, L. Austin Doyle, Steven M. Kornblau, Keith A. Baggerly, Wenbin Liu, Michael Andreeff, Jan A. Burger, LaKiesha Debose, Hongbo Lu, Jennie B. Feliu, Peter P. Ruvolo, Tapan M. Kadia, Xuelin Huang, Gautam Borthakur, Zhihong Zeng, Elias J. Jabbour, Stefan H. Faderl, Roland B. Walter, Marina Y. Konopleva
PDF file - 50KB, Correlation between RPPA and immunoblotting in samples from the patients treated on MK-2206 trial.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b5b44254b7581e9f686bbaa95ef77d
https://doi.org/10.1158/1078-0432.22450359
https://doi.org/10.1158/1078-0432.22450359
Autor:
Hagop M. Kantarjian, Elihu H. Estey, L. Austin Doyle, Steven M. Kornblau, Keith A. Baggerly, Wenbin Liu, Michael Andreeff, Jan A. Burger, LaKiesha Debose, Hongbo Lu, Jennie B. Feliu, Peter P. Ruvolo, Tapan M. Kadia, Xuelin Huang, Gautam Borthakur, Zhihong Zeng, Elias J. Jabbour, Stefan H. Faderl, Roland B. Walter, Marina Y. Konopleva
PDF file - 62KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25ab8972a3d070380eb0d028ca4feddd
https://doi.org/10.1158/1078-0432.22450353
https://doi.org/10.1158/1078-0432.22450353
Autor:
Hagop M. Kantarjian, Elihu H. Estey, L. Austin Doyle, Steven M. Kornblau, Keith A. Baggerly, Wenbin Liu, Michael Andreeff, Jan A. Burger, LaKiesha Debose, Hongbo Lu, Jennie B. Feliu, Peter P. Ruvolo, Tapan M. Kadia, Xuelin Huang, Gautam Borthakur, Zhihong Zeng, Elias J. Jabbour, Stefan H. Faderl, Roland B. Walter, Marina Y. Konopleva
PDF file - 131KB, Effects of MK-2206 on AKT signaling in FLT3-mutant AML cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51864edad1e7652a8a06876b4c9db637
https://doi.org/10.1158/1078-0432.22450368
https://doi.org/10.1158/1078-0432.22450368
Autor:
Olatoyosi Odenike, Wendy Stock, Richard A. Larson, Walter M. Stadler, L. Austin Doyle, Scott E. Smith, Sachdev P. Thomas, Philip Dy, Ehab L. Atallah, Loren Joseph, Poluru L. Reddy, Kevin Shannon, Greg Koval, Xavier Poire, Margaret Green, Harry P. Erba, Theodore Karrison, Mark H. Kirschbaum, Leslie Popplewell, Rangesh Kunnavakkam, Ernesto Diaz-Flores, Neil M. Iyengar, Emily Curran, Nitin Jain
PDF file - 339K, Flow cytometry histograms of serial levels of p-ERK and p-mTOR in patient samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942e3eb94da5a8d19a61ca810d5f59a7
https://doi.org/10.1158/1078-0432.22448649.v1
https://doi.org/10.1158/1078-0432.22448649.v1