Zobrazeno 1 - 3
of 3
pro vyhledávání: '"L A Bentolila"'
Publikováno v:
The Journal of Immunology. 158:715-723
N region diversity in Ag receptors is a developmentally regulated process in B and T cells that correlates with the differential expression of terminal deoxynucleotidyl transferase (TdT). Absent in fetal and newborn mice, TdT expression is restricted
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(4)
Nontemplated (N) nucleotide additions contribute significantly to the junctional diversity of all Ag receptor chains in adult mice except Ig light (L) chains, primarily because terminal deoxynucleotidyl transferase (TdT) expression is turned off at t
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(12)
During neonatal life, Ig diversity is limited in many respects. The absence of terminal deoxynucleotidyl transferase (TdT) expression with the consequent lack of nontemplated addition during the neonatal period, coupled with the predominant usage of