Zobrazeno 1 - 10
of 85
pro vyhledávání: '"L A Aarden"'
Publikováno v:
Hämostaseologie. 32:51-55
SummaryFactor VII-activating protease (FSAP) is a serine protease in plasma that has a role in coagulation and fibrinolysis. FVII could be activated by purified FSAP in a tissue factor independent manner and pro-urokinase has been demonstrated to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a4a552f7d9476680df8c5d5cc579c8
https://doi.org/10.5482/ha-1187
https://doi.org/10.5482/ha-1187
Autor:
J.C. van Denderen, Mike J L Peters, Gertjan Wolbink, L. A. Aarden, Ben A. C. Dijkmans, M.K. de Vries, Michael T. Nurmohamed, S.O. Stapel, I E van der Horst-Bruinsma
Publikováno v:
Annals of the rheumatic diseases, 68(4), 531-535. BMJ Publishing Group
de Vries, M K, van der Horst-Bruinsma, I E, Nurmohamed, M T, Aarden, L, Stapel, S N, Peters, M J L, van Denderen, A C, Dijkmans, B A C & Wolbink, G 2009, ' Immunogenicity does not influence treatment with etanercept in patients with ankylosing spondylitis ', Annals of the Rheumatic Diseases, vol. 68, no. 4, pp. 531-535 . https://doi.org/10.1136/ard.2008.089979
Annals of the Rheumatic Diseases, 68(4), 531-535. BMJ Publishing Group
de Vries, M K, van der Horst-Bruinsma, I E, Nurmohamed, M T, Aarden, L, Stapel, S N, Peters, M J L, van Denderen, A C, Dijkmans, B A C & Wolbink, G 2009, ' Immunogenicity does not influence treatment with etanercept in patients with ankylosing spondylitis ', Annals of the Rheumatic Diseases, vol. 68, no. 4, pp. 531-535 . https://doi.org/10.1136/ard.2008.089979
Annals of the Rheumatic Diseases, 68(4), 531-535. BMJ Publishing Group
Background:Immunogenicity, specifically the onset of antibodies against tumour necrosis factor (TNF) blocking agents, seems to play an important role in non-response to treatment with these drugs.Objectives:To assess the relation of clinical response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ff130e82aa3c95a599190b27b814ab
https://doi.org/10.1136/ard.2008.089979
https://doi.org/10.1136/ard.2008.089979
Publikováno v:
Oral microbiology and immunology, 22(3), 145-151. Wiley-Blackwell
Oral Microbiology and Immunology, 22(3), 145-151. Wiley-Blackwell
Kikkert, R, Laine, M L, Aarden, L A & van Winkelhoff, A J 2007, ' Activiation of toll-like receptors 2 and 4 by gram-negative periodontal bacteria ', Oral Microbiology and Immunology, vol. 22, no. 3, pp. 145-151 . https://doi.org/10.1111/j.1399-302X.2007.00335.x
Oral Microbiology and Immunology, 22(3), 145-151. Wiley-Blackwell
Kikkert, R, Laine, M L, Aarden, L A & van Winkelhoff, A J 2007, ' Activiation of toll-like receptors 2 and 4 by gram-negative periodontal bacteria ', Oral Microbiology and Immunology, vol. 22, no. 3, pp. 145-151 . https://doi.org/10.1111/j.1399-302X.2007.00335.x
Background/aims: Periodontitis is a chronic infectious disease associated with a gram-negative subgingival microflora. Bacterial components stimulate, among other receptors, Toll-like receptor (TLR) 2 and/or TLR4. Accumulating evidence indicates that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0baa40183d535b16bd481687bd966867
https://doi.org/10.1111/j.1399-302x.2007.00335.x
https://doi.org/10.1111/j.1399-302x.2007.00335.x
Autor:
R J van de Stadt, I E van der Horst-Bruinsma, M M J Nielen, A R van der Horst, Dörte Hamann, L. A. Aarden, D. van Schaardenburg, B A C Dijkmans
Publikováno v:
Annals of the rheumatic diseases, 64(8), 1199-1204. BMJ Publishing Group
Annals of the Rheumatic Diseases, 64(8), 1199-1204. BMJ Publishing Group
Nielen, MM, van der Horst, A R, van Schaardenburg, D, van der Horst-Bruinsma, I E, van de Stadt, RJ, Aarden, L A, Dijkmans, B A C & Hamann, D 2005, ' Antibodies to citrullinated human fibrinogen (ACF) have diagnostic and prognostic value in early arthritis ', Annals of the Rheumatic Diseases, vol. 64, no. 8, pp. 1199-1204 . https://doi.org/10.1136/ard.2004.029389
Annals of the Rheumatic Diseases, 64(8), 1199-1204. BMJ Publishing Group
Nielen, MM, van der Horst, A R, van Schaardenburg, D, van der Horst-Bruinsma, I E, van de Stadt, RJ, Aarden, L A, Dijkmans, B A C & Hamann, D 2005, ' Antibodies to citrullinated human fibrinogen (ACF) have diagnostic and prognostic value in early arthritis ', Annals of the Rheumatic Diseases, vol. 64, no. 8, pp. 1199-1204 . https://doi.org/10.1136/ard.2004.029389
Background: The anti-cyclic citrullinated peptide (CCP) test has a high sensitivity and specificity for rheumatoid arthritis, although CCP is not the physiological target of the autoantibodies. Citrullinated fibrin is abundant in inflamed synovium Ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bdf3639b6f07c1ae9b03e9581fac3a9
https://hdl.handle.net/1871/23200
https://hdl.handle.net/1871/23200
Autor:
L. A. Aarden, A. E. Alewijnse, L. C. M. Boeije, E. de Groot, A. Snijders, T C T M van der Pouw Kraan, R. (Rob) Leurs
Publikováno v:
Journal of Clinical Investigation, 102(10), 1866-1873. The American Society for Clinical Investigation
Journal of clinical investigation, 102(10), 1866-1873. The American Society for Clinical Investigation
van der Pouw Kraan, C T M, Snijders, A, Boeije, L C M, Groot, E R, Alewijnse, A E, Leurs, R & Aarden, L A 1998, ' Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. ', Journal of Clinical Investigation, vol. 102, no. 10, pp. 1866-1873 . https://doi.org/10.1172/JCI3692
Journal of clinical investigation, 102(10), 1866-1873. The American Society for Clinical Investigation
van der Pouw Kraan, C T M, Snijders, A, Boeije, L C M, Groot, E R, Alewijnse, A E, Leurs, R & Aarden, L A 1998, ' Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. ', Journal of Clinical Investigation, vol. 102, no. 10, pp. 1866-1873 . https://doi.org/10.1172/JCI3692
IL-12 is essential for T helper 1 (Th1) development and inhibits the induction of Th2 responses. Atopic diseases, which are characterized by Th2 responses, are associated with the overproduction of histamine. Here we present evidence that histamine,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6033fac61ec7b992f3e32c9f8a14ebd0
https://hdl.handle.net/1871/21567
https://hdl.handle.net/1871/21567
Publikováno v:
Blood. 87:5051-5060
Acute inflammatory illnesses, including the sepsis syndrome, often include a component of coagulation. A human whole blood culture system was developed so that the relationship between coagulation activation and cytokine responses in the presence or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fa65d674fbbc1c28f2701a77af9f9b8
https://doi.org/10.1182/blood.v87.12.5051.bloodjournal87125051
https://doi.org/10.1182/blood.v87.12.5051.bloodjournal87125051
Publikováno v:
The Journal of Immunology. 156:4401-4407
Leukemia inhibitory factor (LIF), a pleiotropic cytokine with many biologic effects overlapping with those of IL-6, has been implicated in the pathogenesis of sepsis. We here analyzed the kinetics of LIF in 13 baboons challenged with a lethal (n=6) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95d4e51d1e7d15019cd417876a7fa661
https://doi.org/10.4049/jimmunol.156.11.4401
https://doi.org/10.4049/jimmunol.156.11.4401
Publikováno v:
The Journal of Immunology. 156:1818-1823
IL-13, a T cell-derived cytokine, shares many of its biologic activities with the Th2 cytokine IL-4, including induction of a class switch to IgE and anti-inflammatory properties. Its potential impact on development of Th2 responses makes it interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19564fa2da80a0ca7703738540a11975
https://doi.org/10.4049/jimmunol.156.5.1818
https://doi.org/10.4049/jimmunol.156.5.1818
Publikováno v:
Clinical and Experimental Immunology. 99:473-478
SUMMARY In lymphocyte cultures, IgE production was achieved by stimulating T cells with anti-CD2 and IL-2. Here we show that anti-CD28, in the presence or absence of IL-2, reduces this IgE production approximately 10-fold. This inhibition of IgE prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa78d0110df16555a56c2d0ce5adf3e
https://doi.org/10.1111/j.1365-2249.1995.tb05575.x
https://doi.org/10.1111/j.1365-2249.1995.tb05575.x
Publikováno v:
Clinical and experimental immunology, 97(2), 254-259. Wiley-Blackwell
SUMMARYTo analyse whether there is a general defect in T or B cell function in atopic individuals we have measured cytokine and IgE production by peripheral blood lymphocytes, isolated from 19 atopic donors (17 asthma/rhinitis and two dermatitis pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99a0da1d829aa90b64b25e3c3865ebe
https://doi.org/10.1111/j.1365-2249.1994.tb06077.x
https://doi.org/10.1111/j.1365-2249.1994.tb06077.x