Zobrazeno 1 - 10
of 24
pro vyhledávání: '"L A, Tell"'
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 38(3)
Allometric scaling is widely used for the determination of first dosage regimen and the interpolation or extrapolation of pharmacokinetic parameters across many animal species during drug development. In this article, 85 drugs used in veterinary medi
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 62
Flunixin, a widely used non-steroidal anti-inflammatory drug, was a leading cause of violative residues in cattle. The objective of this analysis was to explore how the changes in pharmacokinetic (PK) parameters that may be associated with diseased a
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 36(3)
The objective of this study was to develop a population pharmacokinetic (PK) model and predict tissue residues and the withdrawal interval (WDI) of flunixin in cattle. Data were pooled from published PK studies in which flunixin was administered thro
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 36(2)
Six adult male alpacas received one subcutaneous administration of ceftiofur crystalline free acid (CCFA) at a dosage of 6.6 mg/kg. After a washout period, the same alpacas received three subcutaneous doses of 6.6 mg/kg CCFA at 5-day intervals. Blood
Autor:
M, Leclere, K G, Magdesian, C A, Cole, N J, Szabo, R E, Ruby, D M, Rhodes, J, Edman, A, Vale, W D, Wilson, L A, Tell
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 35(6)
Azithromycin is widely used in foals but has not been studied in adult horses. The goals of this study were to determine the pharmacokinetic profile and to make a preliminary assessment of the safety of azithromycin in adult horses. Azithromycin was
Autor:
K A, Clothier, T, Leavens, R W, Griffith, S E, Wetzlich, R E, Baynes, J E, Riviere, L A, Tell
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 35(2)
Tulathromycin is a macrolide antimicrobial labeled for treatment of bacterial pneumonia in cattle and swine. The purpose of the present research was to evaluate tissue concentrations of tulathromycin in the caprine species. A tandem mass spectrometry
Pharmacokinetics of veterinary drugs in laying hens and residues in eggs: a review of the literature
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 34(6)
Poultry treated with pharmaceutical products can produce eggs contaminated with drug residues. Such residues could pose a risk to consumer health. The following is a review of the information available in the literature regarding drug pharmacokinetic
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 35(2)
Physiologically based pharmacokinetic (PBPK) models, which incorporate species- and chemical-specific parameters, could be useful tools for extrapolating withdrawal times for drugs across species and doses. The objective of this research was to devel
Autor:
K A, Clothier, T, Leavens, R W, Griffith, S E, Wetzlich, R E, Baynes, J E, Riviere, L A, Tell
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 34(5)
Tulathromycin, a novel triamilide in the macrolide class, is labeled for treatment of bacterial pneumonia in cattle and swine. This manuscript evaluates pharmacokinetics of tulathromycin in goats. In two different studies, six juvenile and ten market
Publikováno v:
Journal of veterinary pharmacology and therapeutics. 34(4)
Ceftiofur, a third generation cephalosporin, demonstrates in vitro efficacy against microorganisms isolated from septicemic neonatal foals. This pharmacokinetic study evaluated the intravenous and subcutaneous administration of ceftiofur sodium (5 mg