Zobrazeno 1 - 10
of 325
pro vyhledávání: '"L A, Rubio"'
Autor:
Sergio Muñoz, Sonia Barroso, Nibal Badra-Fajardo, José Javier Marqueta-Gracia, María L. García-Rubio, Patricia Ubieto-Capella, Juan Méndez, Andrés Aguilera
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113778- (2024)
Summary: During genome duplication, replication forks (RFs) can be stalled by different obstacles or by depletion of replication factors or nucleotides. A limited number of histone post-translational modifications at stalled RFs are involved in RF pr
Externí odkaz:
https://doaj.org/article/5cd5f967db0f4b3486274166c63a0bf2
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/e06dc8e6a4584725ab2c97086fac24bc
Autor:
Seong-Su Han, Kuo-Kuang Wen, María L. García-Rubio, Marc S. Wold, Andrés Aguilera, Wojciech Niedzwiedz, Yatin M. Vyas
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Cancer develops in Wiskott-Aldrich syndrome (WAS). Here the authors identify a role for WAS-protein (WASp) in the DNA stress-resolution pathway by promoting the function of Replication Protein A at replication forks after DNA damage.
Externí odkaz:
https://doaj.org/article/6e499727fe454b339e1196dece4c37d7
Autor:
Natalia Ante‐Ardila, Camilo Novoa Garnica, Paola Mora Umaña, Olga Lucía Baquero Castañeda, Alexandra Jiménez Cháves, Melisa Sofía Naranjo, Juan G. Piñeros, Carolina Bonilla, Luz M. Mejía, María L. Mesa‐Rubio, Sonia Restrepo‐Gualteros, Pedro Barrera, Sergio Moreno‐Lopez, Paola Rueda‐Guevara, Andrea Ramírez Varela, FARA Group
Publikováno v:
Health Science Reports, Vol 6, Iss 4, Pp n/a-n/a (2023)
Abstract Background and Aims Acute respiratory failure (ARF) is a common cause of morbimortality, and a frequent reason for admission to the pediatric intensive care unit (PICU). It requires a high‐flow oxygen device as treatment. Our aim is to det
Externí odkaz:
https://doaj.org/article/f15e9e55ea3d4fe68d55d9ea87639dd0
Autor:
Esther Marchena-Cruz, Lola P. Camino, Jay Bhandari, Sónia Silva, José Javier Marqueta-Gracia, Shahad A. Amdeen, Cristina Guillén-Mendoza, María L. García-Rubio, José M. Calderón-Montaño, Xiaoyu Xue, Rosa Luna, Andrés Aguilera
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112148- (2023)
Summary: Unscheduled R loops can be a source of genome instability, a hallmark of cancer cells. Although targeted proteomic approaches and cellular analysis of specific mutants have uncovered factors potentially involved in R-loop homeostasis, we rep
Externí odkaz:
https://doaj.org/article/379f807c97824e0b8643cc5e0824a789
Autor:
E.J. Laserna-Mendieta, S. Salvador-Martín, A. Arias, B. López-Cauce, I. Marín-Jiménez, L.A. Menchén, L. Marín-Rubio, J. Ontañón Rodríguez, L.A. López-Fernández, A.J. Lucendo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114225- (2023)
Background: To predict primary failure of infliximab (IFX) therapy in Crohn’s disease (CD) and to identify patients who maintain long-term effectiveness to IFX is currently not feasible. Some genetic variations are proposed as potential biomarkers.
Externí odkaz:
https://doaj.org/article/d6d2210f71084fc8b1fd2ca54f227447
Publikováno v:
International Transactions on Electrical Energy Systems, Vol 2023 (2023)
In the next decade, the demand for copper is expected to grow by 25%, posing a challenge for mining facilities to increase their production by opening new mines or upgrading existing ones. To optimize the electrical infrastructure of mining facilitie
Externí odkaz:
https://doaj.org/article/4a347308c35b4998a5e2ef0561462ada
Autor:
V. Medrano Martínez, I. Francés Pont, L. Hernández Rubio, L. González Fernández, S. Fernández Izquierdo, J. Mallada Frechin
Publikováno v:
Neurología (English Edition), Vol 36, Iss 9, Pp 692-697 (2021)
Objectives: The Migraine Disability Assessment (MIDAS) questionnaire is the most frequently used instrument for assessing the level of disability in studies into migraine. This study aims to determine the level of completion of the questionnaire, ass
Externí odkaz:
https://doaj.org/article/96ccd04fb5e54ea1abccb91a6d100863
Autor:
Victoria E. Barrios-López, Osvaldo D. Castelán-Martínez, Rocío L. Arteaga-Rubio, María F. Hidalgo-Martínez, Karla M. Silva-Jivaja, Gilberto Castañeda-Hernández, Miguel A. Palomo-Collí
Publikováno v:
Boletín Médico del Hospital Infantil de México, Vol 79, Iss 3 (2022)
Background: Due to many antineoplastic drugs’ toxicity and narrow therapeutic window, medication errors are a health concern in pediatric oncology patients. This study aimed to identify and classify medication errors in a pediatric inpatient chemot
Externí odkaz:
https://doaj.org/article/1dfcab85d9d344bfb4232886bd09ae99
Autor:
L. Chocarro, E. Blanco, H. Arasanz, L. Fernández-Rubio, A. Bocanegra, M. Echaide, M. Garnica, P. Ramos, G. Fernández-Hinojal, R. Vera, G. Kochan, D. Escors
Publikováno v:
Immuno-Oncology and Technology, Vol 14, Iss , Pp 100079- (2022)
Lymphocyte-activated gene 3 (LAG-3) is a cell surface inhibitory receptor and a key regulator of immune homeostasis with multiple biological activities related to T-cell functions. LAG-3 is considered a next-generation immune checkpoint of clinical i
Externí odkaz:
https://doaj.org/article/80ce4a67a31d4e56828ca7465f64cdde