Zobrazeno 1 - 10
of 36
pro vyhledávání: '"L A, Mulieri"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 263:H503-H510
2,3-Butanedione monoxime (BDM) exerts a marked negative inotropic effect and has been shown to have protective actions on human myocardial force production that may be of clinical use. To determine the underlying mechanisms, we studied the effects of
Publikováno v:
Heart rate as a determinant of cardiac function ISBN: 9783642470721
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09523c8a836c151bf5d58d876d0ef757
https://doi.org/10.1007/978-3-642-47070-7_2
https://doi.org/10.1007/978-3-642-47070-7_2
Publikováno v:
Advances in experimental medicine and biology. 453
Stretch activation, which underlies the ability of all striated muscles to do oscillatory work, is a prominent feature of both insect flight and vertebrate cardiac muscle. We have examined and compared work-producing and work-absorbing processes in s
Autor:
N R, Alpert, L A, Mulieri
Publikováno v:
Advances in experimental medicine and biology. 430
Thin muscle strips were obtained from non-failing (NF) and failing (dilated cardiomyopathy (DCM)) hearts, using a new harvesting and dissection technique. The strips were used to carry out a myothermal and mechanical analysis so that contractile and
Publikováno v:
European heart journal. 16
In hypertrophied and failing hearts there are major changes in the overall contractile performance. We present a review of our previous work relating the alterations in myocardial force, work, power and relaxation, that lead to changes in overall ven
Publikováno v:
Basic research in cardiology. 88
Under normal conditions the cardiac output is designed to meet the metabolic needs of the organism. Thus, the demands imposed on the heart muscle can range from low values at rest to an order of magnitude greater values during exercise. The heart use
Publikováno v:
Basic research in cardiology. 88
Myocardial adaptation to stress and development includes reorganization of subcellular systems. Using a myothermal method, changes in the contractile protein system were investigated across species (rat, rabbit, human myocardium) and in consequence o
Autor:
L. A. Mulieri, Norman R. Alpert, Gerd Hasenfuss, Frank P. Ittleman, Bruce J. Leavitt, Blanchard E
Publikováno v:
European heart journal. 13
A myothermal/mechanical analysis on non-failing and failing human hearts and normal and pressure overloaded rabbit hearts is reported. Heat production is partitioned into tension-dependent and tension-independent components together with force measur
Publikováno v:
Basic research in cardiology. 87
Isometric heat and force measurements were used to relate mechanical performance to function of contractile proteins in muscle strips from failing and nonfailing human hearts (37 degrees C, 60 beats per minute). Compared to control myocardium, crossb
Publikováno v:
Basic research in cardiology. 87
We studied isometric twitch tension and diastolic tension at 37 degrees C as a function of stimulation frequency (12-240 min-1) in very thin (.07-.5 mm2), parallel fibered strips of left-ventricular myocardium. Non-failing control tissue (C) was obta