Zobrazeno 1 - 6 of 6 pro vyhledávání: '"L A, Kachnic"'
1
Adjuvant gemcitabine and concurrent radiation for patients with resected pancreatic cancer: a phase II study
Autor: L A Kachnic, L D Case, Joel E. Tepper, C Partensky, Edward A. Levine, Susan A. Melin, Girish Mishra, L Descos, S A Limentani, F Mornex, A W Blackstock
Publikováno v: British Journal of Cancer
The safety and efficacy of gemcitabine and concurrent radiation to the upper abdomen followed by weekly gemcitabine in patients with resected pancreatic cancer was determined. Patients with resected adenocarcinoma of the pancreas were treated with in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e26eed8777a82164d63532064c9047b
https://doi.org/10.1038/sj.bjc.6603270
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3
The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase
Autor: L A, Kachnic, B, Wu, H, Wunsch, K L, Mekeel, J S, DeFrank, W, Tang, S N, Powell
Publikováno v: The Journal of biological chemistry. 274(19)
scid mouse embryonic fibroblasts are deficient in DNA-dependent protein kinase activity due to a mutation in the C-terminal domain of the catalytic subunit (DNA-PKcs). When exposed to ionizing radiation, the increase in levels of p53 was the same as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e7b1a56e287c8313a7caa2a0d8974c49
https://pubmed.ncbi.nlm.nih.gov/10224064
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5
Combined modality treatment with selective bladder conservation for invasive bladder cancer: long-term tolerance in the female patient
Autor: L A, Kachnic, W U, Shipley, P P, Griffin, A L, Zietman, D S, Kaufman, A F, Althausen, N M, Heney
Publikováno v: The cancer journal from Scientific American. 2(2)
To assess the physical, psychological, social, and organ-specific long-term treatment sequelae occurring in women with muscle-invading bladder carcinoma treated with combined modality therapy that allowed for bladder conservation in 67% of patients.P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a694b88265db52fbba87dd72cdd77c37
https://pubmed.ncbi.nlm.nih.gov/9166504
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