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pro vyhledávání: '"L A, Fields"'
The matrix metalloproteinase (MMP) family has been implicated in the process of a variety of diseases such as arthritis, atherosclerosis, and tumor cell metastasis. We have been designing single-stranded peptides (SSPs) and triple-helical peptides (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48c1659eb4e50b02f159d647c3ee798
https://ora.ox.ac.uk/objects/uuid:edaa2b38-cffa-4500-b435-1037fbeea7bc
https://ora.ox.ac.uk/objects/uuid:edaa2b38-cffa-4500-b435-1037fbeea7bc
Publikováno v:
Journal of Risk and Insurance. 79:931-962
We investigate how investor protection, government quality, and contract enforcement affect risk taking and performance of insurance companies from around the world. We find that better investor protection results in less risk taking, as do higher qu
Publikováno v:
Journal of Banking & Finance. 36:1536-1547
We analyze the relation between comprehensive measures of board quality and the cost as well as the non-price terms of bank loans. We show that firms that have higher quality boards with a greater advisory presence borrow at lower interest rates. Thi
Publikováno v:
Chemical Biology & Drug Design. 74:473-482
Polyphenolic natural products from green tea and red wine have been identified as metalloproteinase inhibitors. Members from the flavonoid and stilbene families found to possess metalloproteinase inhibitory activities include (-)-epigallocatechin gal
Autor:
Peter Chase, Dmitriy Minond, Janelle L. Lauer-Fields, Gregg B. Fields, Roma Stawikowska, Peter Hodder, S. Adrian Saldanha, Pierre Baillargeon
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:990-1005
The major components of the cartilage extracellular matrix are type II collagen and aggrecan. Matrix metalloproteinase 13 (MMP-13) has been implicated as the protease responsible for collagen degradation in cartilage during osteoarthritis (OA). In th
Autor:
L. Paige Fields, Manu Gupta
Publikováno v:
Journal of Business Finance & Accounting. 36:161-184
As is evident from recent changes in NYSE and NASDAQ listing requirements, board independence is assumed to be an important and effective governance mechanism. However, the empirical evidence regarding the value of board independence is mixed. We exa
Publikováno v:
The Journal of Peptide Research. 65:272-283
The synthesis of 5-hydroxylysine (Hyl) derivatives for incorporation by solid-phase methodologies presents numerous challenges. Hyl readily undergoes intramolecular lactone formation, and protected intermediates often have poor solubilities. The goal
Publikováno v:
Journal of Corporate Finance. 14:475-483
We extend the literature regarding the importance of corporate governance and bank monitoring by examining the association between loan announcement wealth effects and the corporate governance characteristics of the borrowers. Using a sample of over
Autor:
Gregg B. Fields, Keith Brew, John K. Whitehead, Shunzi Li, Robert P. Hammer, Janelle L. Lauer-Fields
Publikováno v:
Journal of Biological Chemistry. 283:20087-20095
Unregulated activities of the matrix metalloproteinase (MMP) family have been implicated in primary and metastatic tumor growth, angiogenesis, and pathological degradation of extracellular matrix components, such as collagen and laminin. However, cli
Autor:
Janelle L. Lauer-Fields, Gregg B. Fields, Hideaki Nagase, Peter Chase, Gayle D. Burstein, Mare Cudic, Timothy P. Spicer, Peter Hodder
Publikováno v:
Analytical Biochemistry. 373:43-51
Osteoarthritis (OA)1 is an age-related debilitating disease affecting more than 80% of people over the age of 75, and is caused by the destruction of articular cartilage [1]. Extracellular matrix (ECM) proteins make up approximately 90% of the dry we