Zobrazeno 1 - 10
of 43
pro vyhledávání: '"L A, Damani"'
Publikováno v:
Chromatographia. 48:797-802
A simple and specific high-performance liquid chromatographic (HPLC) method for the analysis of ketotifen in aqueous solutions and silicon oil suspensions is described. The HPLC system is based on a reversed phase μBondapak C18 (30×0.39 cm) column
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e14a6b4431bf86d38c99d51ac1183d7
https://doi.org/10.1007/bf02467650
https://doi.org/10.1007/bf02467650
Publikováno v:
Chromatographia. 48:664-670
A robust, sensitive reverse-phase high-performance liquid chromatographic (HPLC) method for the quantification of the majorin vitro oxidative microsomal metabolites of the prochiral tertiary amineN-ethyl-N-methyllaniline (EMA) is described. The analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca7ff0c0a222ccdae76b7b3cfaea149
https://doi.org/10.1007/bf02467596
https://doi.org/10.1007/bf02467596
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 704:315-323
A sensitive and specific high-performance liquid chromatographic (HPLC) assay has been developed for the quantification of 2-methoxyphenylmetyrapone (2-MPMP) and its seven potential metabolites in rat urine and whole blood. 2-MPMP, 2-hydroxyphenylmet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288c61df9d890b54b64c0546af1feaa4
https://doi.org/10.1016/s0378-4347(97)00491-x
https://doi.org/10.1016/s0378-4347(97)00491-x
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 696:69-74
An improved, more efficient method for the determination of metoprolol and its two metabolites in human urine is reported. The simultaneous analysis of the zwitterionic metoprolol acidic metabolite (III, H117/04) with the basic metabolites alpha-hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc2cb60458af956f29d25d820a506a3
https://doi.org/10.1016/s0378-4347(97)00059-5
https://doi.org/10.1016/s0378-4347(97)00059-5
Publikováno v:
Pharmaceutical Research. 13:179-182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dd5d99c41cd79bd3d8747f1e4ccb49a
https://doi.org/10.1023/a:1016018409546
https://doi.org/10.1023/a:1016018409546
Publikováno v:
Chirality. 8:430-440
The prochiral tertiary amine N-ethyl-N-methylaniline (EMA) is known to be stereoselectively N-oxygenated in the presence of hepatic microsomal preparations. This biotransformation is thought to be mediated predominantly by the flavin-containing monoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9505940ac06ec71e94ecc9cbeee50d8e
https://doi.org/10.1002/(sici)1520-636x(1996)8:6<430::aid-chir4>3.0.co
https://doi.org/10.1002/(sici)1520-636x(1996)8:6<430::aid-chir4>3.0.co
Publikováno v:
Xenobiotica. 26:211-219
1. The metabolism of 1-(2-methoxyphenyl)-2-methyl-2-(3-pyridyl)-1-propanone (2-MPMP) was studied in the male Sprague-Dawley rat after 50 mg/kg, i.v. dose. 2. Organic solvent extracts of urine samples were directly analysed by reversed-phase gradient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5012566004e46d081ea18962fe7036d
https://doi.org/10.3109/00498259609046701
https://doi.org/10.3109/00498259609046701
Autor:
Satvinder K. Bhasin, Andrew J. Hutt, L. A. Damani, Jo Murphy, Patrick Camilleri, Ryta A. Kuzel, Harriet G. Oldham
Publikováno v:
Chirality. 6:607-614
The individual enantiomers of cimetidine sulfoxide were resolved by preparative chromatography using a Chiralcel OC stationary phase and were characterized by the determination of optical rotation and circular dichroism spectra. Cimetidine sulfoxide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dec8d61d6ae95806505bdc7b120099d
https://doi.org/10.1002/chir.530060802
https://doi.org/10.1002/chir.530060802
Publikováno v:
Chirality. 6:98-104
The prochiral tertiary amine N-ethyl-N-methylaniline (EMA) is known to be metabolically N-oxygenated in vitro with microsomal preparations. This biotransformation is thought to be mediated predominantly by the flavin-containing monooxygenase (FMO) en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de345ec32fcb3eb08dd93bf12363f7ca
https://doi.org/10.1002/chir.530060210
https://doi.org/10.1002/chir.530060210
Autor:
L. A. Damani, Andrew J. Hutt, Mark R. Hadley, J. Murphy, Patrick Camilleri, Harriet G. Oldham
Publikováno v:
Chromatographia. 37:487-491
A high-performance liquid chromatographic method for the resolution of the enantiomers of a series ofN-alkyl-N-methylanilineN-oxides is reported. The resolutions were achieved using a Chiralcel, OD chiral stationary-phase with a mobile-phase of hexan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c7b9981f841ba7d17eaf54839c8685
https://doi.org/10.1007/bf02275784
https://doi.org/10.1007/bf02275784