Antiproliferative effect of mifepristone (RU486) on human neuroblastoma cells (SK-N-SH): in vitro and in vivo studies

Autor: Flavio Piva, M. Piccolella, M. Milani, G. Pratesi, L. A. Casulari, Roberto Maggi, Donatella Dondi

Publikováno v: Brazilian Journal of Medical and Biological Research v.53 n.11 2020
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Brazilian Journal of Medical and Biological Research, Volume: 53, Issue: 11, Article number: e10067, Published: 07 OCT 2020
Brazilian Journal of Medical and Biological Research, Vol 53, Iss 11 (2020)

RU486 (mifepristone), a glucocorticoid and progesterone receptor antagonist, has been reported to exert antiproliferative effects on tumor cells. Experiments were performed to analyze the effects of RU486 on the proliferation of the human neuroblasto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074307a0739363932ec16570add9c99b
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020001100606

New insight on the molecular aspects of glucocorticoid effects in nervous system development

Autor: R, Maggi, D, Dondi, M, Piccolella, L A, Casulari, L, Martini

Publikováno v: Journal of endocrinological investigation. 36(9)

Adrenal glucocorticoids (Gc) are among the most significant hormones in the mammalian organisms; these steroids may reach and penetrate all tissues where they interact with cytoplasmic/nuclear receptors, through which they exert multiple and very mul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3a74d662675d2d594cbe99422df87639
https://pubmed.ncbi.nlm.nih.gov/23765505

Effects of low-dose of niacin associated to simvastatin in the treatment of mixed dyslipidemia Salgad

Autor: B J, Salgado, J V, Salgado, A M, Dos Santos, L A, Casulari

Publikováno v: Minerva cardioangiologica. 58(5)

The aim of this study was to evaluate the effects of low-dose niacin extended-release (niacin-ER) combined with simvastatin (SV) in the treatment of patients with mixed dyslipidemia who have not normalized their lipid profile with statin therapy alon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0bd84523403cbd005b567c64bd78b5d9
https://pubmed.ncbi.nlm.nih.gov/20948500

Patients with nephrolithiasis and blood hypertension have higher calciuria than those with isolated nephrolithiasis or hypertension?

Autor: M M, Schleicher, M C, Reis, S S, Costa, M Palmeira, Rodrigues, L A, Casulari

Publikováno v: Minerva urologica e nefrologica = The Italian journal of urology and nephrology. 61(1)

The aim of this study was to determine urinary excretion of calcium, uric acid and sodium and to evaluate insulin resistance in patients with nephrolithiasis and blood hypertension, isolated and in association, and in healthy controls, in absence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a858dce3cf02f8011601f3926b6280e7
https://pubmed.ncbi.nlm.nih.gov/19417722

Clinical and laboratory features greatly overlap in patients with macroprolactinemia or monomeric hyperprolactinemia

Autor: L, Vilar, L A, Naves, M C, Freitas, M, Lima, V, Canadas, J L, Albuquerque, R, Lyra, M F, Azevedo, L A, Casulari

Publikováno v: Minerva endocrinologica. 32(2)

The aim of this study was to evaluate the clinical and laboratory features of 64 patients with macroprolactinemia and to compare them to those of individuals with monomeric hyperprolactinemia.The study included 64 patients (54 women and 10 men) with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::769d04176a11fdfa7ad97ffc6ecbb809
https://pubmed.ncbi.nlm.nih.gov/17557033