Zobrazeno 1 - 10
of 16
pro vyhledávání: '"L A, Beltz"'
Autor:
K. P. Manfredi, L. A. Beltz
Publikováno v:
Medicinal Chemistry Reviews - Online. 2:325-343
Autor:
L. A. Beltz
Publikováno v:
Current Medicinal Chemistry-Anti-Cancer Agents. 2:589-603
Human telomeres are several kilobases of repeated (TTAGGG)(n) sequences at the ends of chromosomes, a short fragment of which is lost with each cell division. This shortening serves as a "mitotic clock" which limits the number of divisions that a nor
Publikováno v:
Infection and Immunity. 59:3518-3522
We studied the suppressive effects induced in phytohemagglutinin (PHA)-stimulated human peripheral blood mononuclear cells (PBMC) by purified blood forms of Trypanosoma brucei rhodesiense. The parasite was found to markedly impair lymphocyte prolifer
Autor:
L A, Beltz
Publikováno v:
Current medicinal chemistry. Anti-cancer agents. 2(5)
Human telomeres are several kilobases of repeated (TTAGGG)(n) sequences at the ends of chromosomes, a short fragment of which is lost with each cell division. This shortening serves as a "mitotic clock" which limits the number of divisions that a nor
Publikováno v:
Archives of environmental contamination and toxicology. 43(3)
Nitrate from drinking water is converted in the body to nitrite by bacteria in the gut. This project examined effects of nitrate/nitrite on immune functions, i.e., human lymphocyte proliferation and cytokine production. Nitrate had no effect on lymph
Publikováno v:
Infection and Immunity. 58:1114-1116
Coculture of blood forms of Trypanosoma cruzi with human peripheral blood mononuclear cells stimulated with anti-CD2(2) and anti-CD2(3) monoclonal antibodies, i.e., via an antigen-independent pathway of T-lymphocyte activation, resulted in marked imm
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(10)
Coculture of blood forms of Trypanosoma cruzi with human PMBC suppresses the expression of several molecules involved in lymphocyte activation, including receptors for IL-2. Our work was initially undertaken to establish whether this effect required
Publikováno v:
The Journal of Immunology. 141:289-294
Co-culture of blood forms of Trypanosoma cruzi, the causative agent of Chagas' disease, with human PBMC impaired the capacity of T lymphocytes to express surface receptors for IL-2. This effect was evidenced by marked reductions in both the proportio
Publikováno v:
The Journal of Immunology. 143:275-279
We previously established that Trypanosoma cruzi, the causative agent of Chagas' disease, has the ability to suppress expression of the p55 component of the IL-2R by activated human PBMC. We explored in this work whether the parasite alters the expre
Publikováno v:
The Journal of Protozoology. 35:108-110
Among the known life cycle stages of Trypanosoma cruzi only the amastigote form bound lactoferrin (LF), a glycoprotein produced by neutrophils. This capacity was readily demonstrable by indirect immunofluorescence in amastigotes derived from mice, a