Zobrazeno 1 - 10
of 126
pro vyhledávání: '"L��na, P."'
Different associations between body mass index and Alzheimer’s markers depending on metabolic health
Autor:
Eun Hye Lee, Heejin Yoo, Young Ju Kim, Bo Kyoung Cheon, Seungho Ryu, Yoosoo Chang, Jihwan Yun, Hyemin Jang, Jun Pyo Kim, Hee Jin Kim, Seong-Beom Koh, Jee Hyang Jeong, Duk L. Na, Sang Won Seo, Sung Hoon Kang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Increasing evidence supports the association between body mass index (BMI), Alzheimer’s disease, and vascular markers. Recently, metabolically unhealthy conditions have been reported to affect the expression of these markers. We
Externí odkaz:
https://doaj.org/article/0f8f3d408a744d3e9d9d262fa79fb183
Autor:
Sungjoo Lee, Si Eun Kim, Hyemin Jang, Jun Pyo Kim, Gyeongmo Sohn, Yu Hyun Park, Hongki Ham, Yuna Gu, Chae Jung Park, Hee Jin Kim, Duk L. Na, Kyunga Kim, Sang Won Seo
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Risk factors for cardiovascular disease, including elevated blood pressure, are known to increase risk of Alzheimer’s disease. There has been increasing awareness of the relationship between long-term blood pressure (BP) pattern
Externí odkaz:
https://doaj.org/article/bbb66bfddd1946f9bee91b5a9e3d2f28
Autor:
Min Young Chun, Wonjeong Chae, Sang Won Seo, Hyemin Jang, Jihwan Yun, Duk L. Na, Dongwoo Kang, Jungkuk Lee, Dustin B. Hammers, Liana G. Apostolova, Sung-In Jang, Hee Jin Kim
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Early-onset dementia (EOD, onset age
Externí odkaz:
https://doaj.org/article/15a1bbc55f46489bba78a4e7028d4552
Autor:
Chae Jung Park, Yu Hyun Park, Kichang Kwak, Soohwan Choi, Hee Jin Kim, Duk L. Na, Sang Won Seo, Min Young Chun
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundDetermining brain atrophy is crucial for the diagnosis of neurodegenerative diseases. Despite detailed brain atrophy assessments using three-dimensional (3D) T1-weighted magnetic resonance imaging, their practical utility is limited by cost
Externí odkaz:
https://doaj.org/article/1b9ab131a2854e19a4ae5e9945179b87
Autor:
Je Moon Yoon, Chae Yeon Lim, Hoon Noh, Seung Wan Nam, Sung Yeon Jun, Min Ji Kim, Mi Yeon Song, Hyemin Jang, Hee Jin Kim, Sang Won Seo, Duk L. Na, Myung Jin Chung, Don-Il Ham, Kyungsu Kim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract We propose a hybrid technique that employs artificial intelligence (AI)-based segmentation and machine learning classification using multiple features extracted from the foveal avascular zone (FAZ)—a retinal biomarker for Alzheimer’s dis
Externí odkaz:
https://doaj.org/article/46c628df1fa44558a812bce2ece00128
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Early detection and intervention in individuals in the pre-clinical stage of dementia are crucial. This study aimed to examine whether there are significant differences in (1) word retrieval, (2) subjective communication ability, (3) interve
Externí odkaz:
https://doaj.org/article/d76b6cd8bb5744839ecb5ccedd4b761b
Autor:
Wonsik Jung, Si Eun Kim, Jun Pyo Kim, Hyemin Jang, Chae Jung Park, Hee Jin Kim, Duk L. Na, Sang Won Seo, Heung-Il Suk
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
ObjectivesAccurately predicting when patients with mild cognitive impairment (MCI) will progress to dementia is a formidable challenge. This work aims to develop a predictive deep learning model to accurately predict future cognitive decline and magn
Externí odkaz:
https://doaj.org/article/36b5b8273ee64b68ab790027a80ac5f1
Autor:
Sung Hoon Kang, Heejin Yoo, Bo Kyoung Cheon, Yu Hyun Park, Soo-Jong Kim, Hongki Ham, Hyemin Jang, Hee Jin Kim, Kyungmi Oh, Seong-Beom Koh, Duk L. Na, Jun Pyo Kim, Sang Won Seo
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-9 (2023)
Abstract Background Cholesterol plays important roles in β-amyloid (Aβ) metabolism and atherosclerosis. However, the relationships of plasma cholesterol levels with Aβ and cerebral small vessel disease (CSVD) burdens are not fully understood in As
Externí odkaz:
https://doaj.org/article/f645d502a6d149b6902a834843b5f5da
Publikováno v:
Leukemia Research Reports, Vol 21, Iss , Pp 100429- (2024)
Introduction: Chronic Myelomonocytic Leukemia (CMML) is a rare, malignant hematopoietic system tumour whose pathogenesis remains unclear. This primarily affects elderly males and may transform into acute myeloid leukemia. Elevated innate immune and i
Externí odkaz:
https://doaj.org/article/5010b2af12df4e9f830ec05602853508
Autor:
Yejoo Choi, Sungho Shin, Hyo Jin Son, Na-Hee Lee, Su Hyeon Myeong, Cheolju Lee, Hyemin Jang, Soo Jin Choi, Hee Jin Kim, Duk L. Na
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Preclinical studies showed that mesenchymal stem cells (MSCs) ameliorate tau phosphorylation, amyloid-beta accumulation, and inflammation in Alzheimer’s disease (AD) mouse models via secretion of neurotrophic factors and cytokin
Externí odkaz:
https://doaj.org/article/aa8ddbb3f9aa44e786115a284096bc19