Efficacy of Endocrine Therapy Plus Trastuzumab and Pertuzumab vs De-escalated Chemotherapy in Patients with Hormone Receptor-Positive/ERBB2-Positive Early Breast Cancer: The Neoadjuvant WSG-TP-II Randomized Clinical Trial.

Autor: Gluz O; West German Study Group, Mönchengladbach, Germany.; Breast Center Niederrhein, Ev. Hospital Bethesda, Mönchengladbach, Germany.; University Clinics Cologne, Cologne, Germany., Nitz UA; West German Study Group, Mönchengladbach, Germany.; Breast Center Niederrhein, Ev. Hospital Bethesda, Mönchengladbach, Germany., Christgen M; Institute of Pathology, Hannover Medical School, Hannover, Germany., Kuemmel S; West German Study Group, Mönchengladbach, Germany.; Breast Unit, Kliniken Essen-Mitte, Essen, Germany.; Department of Gynecology with Breast Center, Charité-Universitätsmedizin Berlin, Berlin, Germany., Holtschmidt J; Breast Unit, Kliniken Essen-Mitte, Essen, Germany.; Breast Center, St Elisabeth-Krankenhaus Köln-Hohenlind, Cologne, Germany., Schumacher J; Statitistics, Palleos Healthcare GmbH, Wiesbaden, Germany., Hartkopf A; Department of Gynecology and Obstetrics, Tüebingen University Hospital, Tüebingen, Germany., Potenberg J; Ev Waldkrankenhaus Berlin, Berlin, Germany., Lüedtke-Heckenkamp K; Department of Oncology and Hematology, Niels Stensen-Kliniken, Georgsmarienhütte, Germany., Just M; Oncological Practice, Bielefeld, Germany., Schem C; Mammazentrum am Krankenhaus Jerusalem, Hamburg, Germany., von Schumann R; Breast Center Niederrhein, Ev. Hospital Bethesda, Mönchengladbach, Germany., Kolberg-Liedtke C; Department of Gynecology with Breast Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.; Women's Clinic, University Clinics Essen, Essen, Germany., Eulenburg CZ; West German Study Group, Mönchengladbach, Germany.; Department of Medical Biometry and Epidemiology, University Medical Center Hamburg, Hamburg, Germany., Schinköthe T; Breast Center, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Munich, Ludwig Maximilians University Hospital, Munich, Germany.; CANKADO Service GmbH, Kirchheim bei München, Germany., Graeser M; West German Study Group, Mönchengladbach, Germany.; Breast Center Niederrhein, Ev. Hospital Bethesda, Mönchengladbach, Germany.; Department of Gynecology, University Medical Center Hamburg, Hamburg, Germany., Wuerstlein R; West German Study Group, Mönchengladbach, Germany.; Breast Center, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Munich, Ludwig Maximilians University Hospital, Munich, Germany., Kates RE; West German Study Group, Mönchengladbach, Germany., Kreipe HH; Institute of Pathology, Hannover Medical School, Hannover, Germany., Harbeck N; West German Study Group, Mönchengladbach, Germany.; Breast Center, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Munich, Ludwig Maximilians University Hospital, Munich, Germany.

Publikováno v: JAMA oncology [JAMA Oncol] 2023 Jul 01; Vol. 9 (7), pp. 946-954.

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HER2-Positive Early Breast Cancer: Time for Ultimate De-Escalation?

Autor: Tauber, Nikolas¹ (AUTHOR) nikolas.tauber@uksh.de, Cirkel, Christoph¹ (AUTHOR), Claussen, Anna¹ (AUTHOR), Fick, Franziska¹ (AUTHOR), Kontomanolis, Emmanuel² (AUTHOR), Krawczyk, Natalia³ (AUTHOR), Rody, Achim¹ (AUTHOR), Banys-Paluchowski, Maggie¹ (AUTHOR)

Publikováno v: Cancers. Mar2024, Vol. 16 Issue 6, p1121. 18p.

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