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Supplementary Movie 2B from Exploratory Clinical Trial of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate for Imaging xC− Transporter Using Positron Emission Tomography in Patients with Non–Small Cell Lung or Breast Cancer

Autor: Dae Hyuk Moon, Sanjiv S. Gambhir, Erik S. Mittra, Ludger M. Dinkelborg, Christoph A. Schatz, Christina Hultsch, Norman Koglin, Lüder Fels, Claudia Bacher-Stier, Seung Jun Oh, Jin-Sook Ryu, Gyungyub Gong, Jong Won Lee, Sei Hyun Ahn, Chang-Min Choi, Sora Baek

AVI, 161K, Maximum intensity projection of 18FFSPG in a breast cancer patient (Patient 13).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f84b67d5b41d74f576418fe404d987
https://doi.org/10.1158/1078-0432.22452335.v1

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Data from Exploratory Clinical Trial of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate for Imaging xC− Transporter Using Positron Emission Tomography in Patients with Non–Small Cell Lung or Breast Cancer

Purpose: (4S)-4-(3-[18F]fluoropropyl)-l-glutamate (BAY 94-9392, alias [18F]FSPG) is a new tracer to image xC− transporter activity with positron emission tomography (PET). We aimed to explore the tumor detection rate of [18F]FSPG in patients relati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c2e0df8b1d663164112aaa27182b42
https://doi.org/10.1158/1078-0432.c.6522446.v1

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Supplementary Figure Legend from Exploratory Clinical Trial of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate for Imaging xC− Transporter Using Positron Emission Tomography in Patients with Non–Small Cell Lung or Breast Cancer

PDF file, 76K, includes movie legends.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a238644c575230892b8f9bafa4e42a7
https://doi.org/10.1158/1078-0432.22452350.v1

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Supplementary Movie 1A from Exploratory Clinical Trial of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate for Imaging xC− Transporter Using Positron Emission Tomography in Patients with Non–Small Cell Lung or Breast Cancer

AVI, 180K, Maximum intensity projection of 18FFSPG in a lung cancer patient (Patient 2).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec7cee1d66cc2ab8730207dbc058b43
https://doi.org/10.1158/1078-0432.22452344.v1

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Supplementary Figures 1 - 5 from Exploratory Clinical Trial of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate for Imaging xC− Transporter Using Positron Emission Tomography in Patients with Non–Small Cell Lung or Breast Cancer

PDF file, 358K, S1: System xC� and CD44 in glutathione biosynthesis and the cysteine-cystine redox cycle; S2: 18FFSPG distribution in normal organs and cancer; S3: Correlation between 18FFDG and 18FFSPG; S4: 18FFDG and 18FFSPG PET in a breast cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09768576956c95cd5c704bf155c7b6e9
https://doi.org/10.1158/1078-0432.22452347.v1

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Supplementary Tables 1 - 2 from Exploratory Clinical Trial of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate for Imaging xC− Transporter Using Positron Emission Tomography in Patients with Non–Small Cell Lung or Breast Cancer

PDF file, 72K, S1: Clinical safety laboratory parameters; S2: Tissue distribution of 18FFSPG.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c4a3e6e36604e27fa7df5edc34e621
https://doi.org/10.1158/1078-0432.22452332

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