Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Lúcio Lara Santos"'
Autor:
Janine Soares, Mariana Eiras, Dylan Ferreira, Daniela A. R. Santos, Marta Relvas-Santos, Beatriz Santos, Martina Gonçalves, Eduardo Ferreira, Renata Vieira, Luís Pedro Afonso, Lúcio Lara Santos, Mário Dinis-Ribeiro, Luís Lima, José Alexandre Ferreira
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3722 (2024)
Colorectal cancer (CRC) screening relies primarily on stool analysis to identify occult blood. However, its sensitivity for detecting precancerous lesions is limited, requiring the development of new tools to improve CRC screening. Carcinogenesis inv
Externí odkaz:
https://doaj.org/article/902ad9232ec54b2ab929909d7a2900e7
Autor:
Francisca Pereira, M. Rosário Domingues, Rui Vitorino, Inês M. S. Guerra, Lúcio Lara Santos, José Alexandre Ferreira, Rita Ferreira
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3347 (2024)
Bladder cancer (BCa) research relying on Omics approaches has increased over the last few decades, improving the understanding of BCa pathology and contributing to a better molecular classification of BCa subtypes. To gain further insight into the mo
Externí odkaz:
https://doaj.org/article/b76e321e87e04715aacb36d681c5975e
Autor:
Eduardo Ferreira, Dylan Ferreira, Marta Relvas-Santos, Rui Freitas, Janine Soares, Rita Azevedo, Luís Pedro Afonso, Luís Lima, Beatriz Santos, Martina Gonçalves, André M. N. Silva, Lúcio Lara Santos, Andreia Peixoto, José Alexandre Ferreira
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3462 (2024)
Muscle-invasive bladder cancer (MIBC) remains a pressing health concern due to conventional treatment failure and significant molecular heterogeneity, hampering the development of novel targeted therapeutics. In our quest for novel targetable markers
Externí odkaz:
https://doaj.org/article/04111be4858b46439bc6d5c0b4de0a0c
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-24 (2022)
Abstract Cancer cells can evade immune responses by exploiting inhibitory immune checkpoints. Immune checkpoint inhibitor (ICI) therapies based on anti-CTLA-4 and anti-PD-1/PD-L1 antibodies have been extensively explored over the recent years to unle
Externí odkaz:
https://doaj.org/article/19c373d9b5e9481fa5200f098b1bc6ee
Autor:
Marta Correia, Ines Moreira, Sonia Cabral, Carolina Castro, Andreia Cruz, Bruno Magalhães, Lúcio Lara Santos, Susana Couto Irving
Publikováno v:
Nutrients, Vol 15, Iss 10, p 2241 (2023)
(1) Background: Gastric cancer patients are known to be at a high risk of malnutrition, sarcopenia, and cachexia, and the latter impairs the patient’s nutritional status during their clinical course and also treatment response. A clearer identifica
Externí odkaz:
https://doaj.org/article/6928cd7581704cfea8e52fe30109e117
Autor:
Andreia Peixoto, Dylan Ferreira, Rita Azevedo, Rui Freitas, Elisabete Fernandes, Marta Relvas-Santos, Cristiana Gaiteiro, Janine Soares, Sofia Cotton, Beatriz Teixeira, Paula Paulo, Luís Lima, Carlos Palmeira, Gabriela Martins, Maria José Oliveira, André M. N. Silva, Lúcio Lara Santos, José Alexandre Ferreira
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-22 (2021)
Abstract Background Muscle invasive bladder cancer (MIBC) remains amongst the deadliest genitourinary malignancies due to treatment failure and extensive molecular heterogeneity, delaying effective targeted therapeutics. Hypoxia and nutrient deprivat
Externí odkaz:
https://doaj.org/article/bc2ddd4248ad4d2798adc87a3fc80212
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Postoperative complications are still hard to predict despite the efforts towards the creation of clinical risk scores. The published scores contribute for the creation of specialized tools, but with limited predictive performance and reusab
Externí odkaz:
https://doaj.org/article/930adffac7d14750b3fa0005b61aa666
Autor:
Mafalda Barbosa Pedrosa, Samuel Barbosa, Rui Vitorino, Rita Ferreira, Daniel Moreira-Gonçalves, Lúcio Lara Santos
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 905 (2023)
Paraneoplastic conditions such as cancer cachexia are often exacerbated by chemotherapy, which affects the patient’s quality of life as well as the response to therapy. The aim of this narrative review was to overview the body-composition-related c
Externí odkaz:
https://doaj.org/article/3fdd41500da546d1a15df548c64183d6
Autor:
Antero Fernandes, Jéssica Rodrigues, Luís Antunes, Patrícia Lages, Carla Salomé Santos, Daniel Moreira-Gonçalves, Rafael S. Costa, Joaquim Abreu Sousa, Mário Dinis-Ribeiro, Lúcio Lara Santos
Publikováno v:
Perioperative Medicine, Vol 9, Iss 1, Pp 1-9 (2020)
Abstract Background Gastrointestinal cancer surgery continues to be a significant cause of postoperative complications and mortality in high-risk patients. It is crucial to identify these patients. Our study aimed to evaluate the accuracy of specific
Externí odkaz:
https://doaj.org/article/216c123258e2423db88fa37d478e3f33
Autor:
Antero Fernandes, Jéssica Rodrigues, Patrícia Lages, Sara Lança, Paula Mendes, Luís Antunes, Carla Salomé Santos, Clara Castro, Rafael S. Costa, Carlos Silva Lopes, Paulo Matos da Costa, Lúcio Lara Santos
Publikováno v:
Patient Safety in Surgery, Vol 13, Iss 1, Pp 1-9 (2019)
Abstract Background Postoperative pulmonary complications (PPCs) contribute significantly to overall postoperative morbidity and mortality. In abdominal surgery, PPCs remain frequent. The study aimed to analyze the profile and outcomes of PPCs in pat
Externí odkaz:
https://doaj.org/article/8e83b5ab20fa4efdac415a32589cea1a