Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins

Autor: Lunde Elin, Løset Geir, Bogen Bjarne, Sandlie Inger

Publikováno v: BMC Biotechnology, Vol 10, Iss 1, p 61 (2010)

Abstract Background Whereas T cell receptors (TCRs) detect peptide/major histocompatibility complexes (pMHCs) with exquisite specificity, there are challenges regarding their expression and use as soluble detection molecules due to molecular instabil

Externí odkaz: https://doaj.org/article/30486c5616994625a37d27d9a9074c10

B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells

Autor: Huszthy, Peter Csaba, Gopalakrishnan, Ramakrishna Prabhu, Jacobsen, Johanne Tracey, Haabeth, Ole Audun Werner, Løset, Geir Åge, Braathen, Ranveig, Schenck, Karl, Tveita, Anders Aune, Munthe, Ludvig Andre, Bogen, Bjarne

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2019 Dec . 116(51), 25850-25859.

Externí odkaz: https://www.jstor.org/stable/26863931

Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease

Autor: Høydahl, Lene Støkken, Richter, Lisa, Frick, Rahel, Snir, Omri, Gunnarsen, Kristin Støen, Landsverk, Ole J.B., Iversen, Rasmus, Jeliazkov, Jeliazko R., Gray, Jeffrey J., Bergseng, Elin, Foss, Stian, Qiao, Shuo-Wang, Lundin, Knut E.A., Jahnsen, Jørgen, Jahnsen, Frode L., Sandlie, Inger, Sollid, Ludvig M., Løset, Geir Åge

Publikováno v: In Gastroenterology April 2019 156(5):1428-1439

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A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation

Autor: Frick, Rahel, Høydahl, Lene Støkken, Petersen, Jan, du Pré, Fleur, Kumari, Shraddha, Berntsen, Grete, Dewan, Alisa Elinsdatter, Jeliazkov, Jeliazko R., Gunnarsen, Kristin Støen, Frigstad, Terje, Vik, Erik S., Llerena, Carmen, Lundin, Knut, Yaqub, Sheraz, Jahnsen, Jørgen, Gray, Jeffrey J., Rossjohn, Jamie, Sollid, Ludvig Magne, Sandlie, Inger, Løset, Geir Åge

Publikováno v: Frick, Rahel Høydahl, Lene Støkken Petersen, Jan du Pré, Fleur Kumari, Shraddha Berntsen, Grete Dewan, Alisa Elinsdatter Jeliazkov, Jeliazko R. Gunnarsen, Kristin Støen Frigstad, Terje Vik, Erik S. Llerena, Carmen Lundin, Knut Yaqub, Sheraz Jahnsen, Jørgen Gray, Jeffrey J. Rossjohn, Jamie Sollid, Ludvig Magne Sandlie, Inger Løset, Geir Åge . A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation. Science immunology. 2021, 6:eabg4925(62), 1-16
Science immunology

Externí odkaz: http://hdl.handle.net/10852/91221
https://www.duo.uio.no/bitstream/handle/10852/91221/2/Frick%252C%2BR.%252C%2Bet%2Bal.%252C%2B2021%252C%2Bpostprint.pdf