New epilepsy therapies in development.

Autor: Klein P; Mid-Atlantic Epilepsy and Sleep Center, Bethesda, MD, USA. kleinp@epilepsydc.com., Kaminski RM; Angelini Pharma, Rome, Italy., Koepp M; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, University College London, London, UK., Löscher W; Translational Neuropharmacology Lab., NIFE, Department of Experimental Otology of the ENT Clinics, Hannover Medical School, Hannover, Germany. Loescher.Wolfgang@mh-hannover.de.; Center for Systems Neuroscience, Hannover, Germany. Loescher.Wolfgang@mh-hannover.de.

Publikováno v: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2024 Sep; Vol. 23 (9), pp. 682-708. Date of Electronic Publication: 2024 Jul 22.

Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and conundrums.

Autor: Kamondi A; National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary. kamondianita@gmail.com.; Department of Neurology, Semmelweis University, Budapest, Hungary. kamondianita@gmail.com., Grigg-Damberger M; Department of Neurology, University of New Mexico, Albuquerque, NM, USA., Löscher W; Department of Experimental Otology of the ENT Clinics, Hannover Medical School, Hannover, Germany., Tanila H; A. I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland., Horvath AA; National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.; Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary.

Publikováno v: Nature reviews. Neurology [Nat Rev Neurol] 2024 Mar; Vol. 20 (3), pp. 162-182. Date of Electronic Publication: 2024 Feb 14.

On hidden factors and design-associated errors that may lead to data misinterpretation: An example from preclinical research on the potential seasonality of neonatal seizures.

Autor: Löscher W; Translational Neuropharmacology Lab, NIFE, Department of Experimental Otology of the ENT Clinics, Hannover Medical School, Hannover, Germany.

Publikováno v: Epilepsia [Epilepsia] 2024 Feb; Vol. 65 (2), pp. 287-292. Date of Electronic Publication: 2023 Dec 11.

A comparison of the antiepileptogenic efficacy of two rationally chosen multitargeted drug combinations in a rat model of posttraumatic epilepsy.

Autor: Hameed MQ; Department of Neurology and FM Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., D'Ambrosio R; Department of Neurological Surgery, University of Washington, Seattle, WA, USA., Eastman C; Department of Neurological Surgery, University of Washington, Seattle, WA, USA., Hui B; Department of Neurology and FM Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Lin R; Department of Neurology and FM Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Vermudez SAD; Department of Neurology and FM Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Liebhardt A; Department of Neurology and FM Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Choe Y; Department of Neurology and FM Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Klein P; PrevEp, Inc., Bethesda, MD, USA; Mid-Atlantic Epilepsy and Sleep Center, Bethesda, MD, USA., Rundfeldt C; PrevEp, Inc., Bethesda, MD, USA., Löscher W; PrevEp, Inc., Bethesda, MD, USA; Translational Neuropharmacology Lab, NIFE, Department of Experimental Otology of the ENT Clinics, Hannover Medical School, Hannover, Germany. Electronic address: Loescher.Wolfgang@mh-hannover.de., Rotenberg A; Department of Neurology and FM Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; PrevEp, Inc., Bethesda, MD, USA. Electronic address: alexander.rotenberg@childrens.harvard.edu.

Publikováno v: Experimental neurology [Exp Neurol] 2024 Dec; Vol. 382, pp. 114962. Date of Electronic Publication: 2024 Sep 15.

Skeletal Muscle Involvement in Friedreich Ataxia.

Autor: Indelicato E; Center for Rare Movement Disorders Innsbruck, Department of Neurology, Medical University of Innsbruck, 6020 Innsbruck, Austria., Wanschitz J; Unit for Neuromuscular Disorders and Clinical Neurophysiology, Department of Neurology, Medical University of Innsbruck, 6020 Innsbruck, Austria., Löscher W; Unit for Neuromuscular Disorders and Clinical Neurophysiology, Department of Neurology, Medical University of Innsbruck, 6020 Innsbruck, Austria., Boesch S; Center for Rare Movement Disorders Innsbruck, Department of Neurology, Medical University of Innsbruck, 6020 Innsbruck, Austria.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Sep 13; Vol. 25 (18). Date of Electronic Publication: 2024 Sep 13.