Hautabszess verursacht durch Actinomyces radingae. (German)

Autor: Davidovic, Miodrag, Ecker, Miriam Eva, Lößlein, Anne Kathrin, Eyerich, Kilian, Schempp, Christoph Mathis

Publikováno v: Die Dermatologie; Jun2024, Vol. 75 Issue 6, p492-495, 4p

Monocyte progenitors give rise to multinucleated giant cells

Autor: Lösslein, Anne Kathrin, Lohrmann, Florens, Scheuermann, Lisa, Gharun, Kourosh, Neuber, Jana, Kolter, Julia, Forde, Aaron James, Kleimeyer, Christian, Poh, Ying Yee, Mack, Matthias, Triantafyllopoulou, Antigoni, Dunlap, Micah D., Khader, Shabaana A., Seidl, Maximilian, Hölscher, Alexandra, Hölscher, Christoph, Guan, Xue Li, Dorhoi, Anca, Henneke, Philipp

Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)

The immune response to mycobacteria is characterized by granuloma formation, which features multinucleated giant cells as a unique macrophage type. We previously found that multinucleated giant cells result from Toll-like receptor-induced DNA damage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b055d68dab1fef21f2342fe2ea648ece
https://hdl.handle.net/21.11116/0000-0008-552F-521.11116/0000-0008-5531-1

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Monocyte progenitors give rise to multinucleated giant cells.

Autor: Lösslein AK; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; MOTI-VATE Graduate School, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Lohrmann F; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Center for Pediatrics and Adolescent Medicine, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Spemann Graduate School for Biology and Medicine (SGBM) and IMM-PACT Clinician Scientist Program, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Scheuermann L; Max Planck Institute for Infection Biology, Berlin, Germany., Gharun K; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Neuber J; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Kolter J; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany., Forde AJ; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Kleimeyer C; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany., Poh YY; Nanyang Technological University, Lee Kong Chian School of Medicine, Singapore, Singapore., Mack M; University Hospital Regensburg, Internal Medicine II, Nephrology, Regensburg, Germany., Triantafyllopoulou A; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Rheumatism Research Centre Berlin, Leibniz Association, Berlin, Germany., Dunlap MD; Department of Molecular Microbiology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA.; Department of Pathology and Immunology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA., Khader SA; Department of Molecular Microbiology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA.; Department of Pathology and Immunology, Washington University in St. Louis School of Medicine, Saint Louis, MO, USA., Seidl M; Center for Chronic Immunodeficiency and Institute for Clinical Pathology, Department of Pathology, Medical Center and Faculty of Medicine, Freiburg, Germany and Institute of Pathology, Heinrich Heine University and University Hospital of Duesseldorf, Duesseldorf, Germany., Hölscher A; Forschungszentrum Borstel, Leibniz Lungenzentrum, Borstel, Germany., Hölscher C; Forschungszentrum Borstel, Leibniz Lungenzentrum, Borstel, Germany.; Deutsches Zentrum für Infektionsforschung, Standort Borstel, Borstel, Germany., Guan XL; Nanyang Technological University, Lee Kong Chian School of Medicine, Singapore, Singapore., Dorhoi A; Max Planck Institute for Infection Biology, Berlin, Germany.; Institute of Immunology, Federal Research Institute for Animal Health, Friedrich-Loeffler-Institut (FLI), Insel Riems, Germany.; Faculty of Mathematics and Natural Sciences, University of Greifswald, Greifswald, Germany., Henneke P; Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany. Philipp.henneke@uniklinik-freiburg.de.; Center for Pediatrics and Adolescent Medicine, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany. Philipp.henneke@uniklinik-freiburg.de.

Publikováno v: Nature communications [Nat Commun] 2021 Apr 01; Vol. 12 (1), pp. 2027. Date of Electronic Publication: 2021 Apr 01.