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The splicing machinery is dysregulated and represents a therapeutic vulnerability in breast cancer.

Autor: Hermán-Sánchez N; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain.; Department of Cell Biology, Physiology, and Immunology, University of Córdoba, Córdoba, 14004, Spain.; Reina Sofía University Hospital, Córdoba, 14004, Spain.; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain., G-García ME; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain.; Department of Cell Biology, Physiology, and Immunology, University of Córdoba, Córdoba, 14004, Spain.; Reina Sofía University Hospital, Córdoba, 14004, Spain.; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain., Jiménez-Vacas JM; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain.; Department of Cell Biology, Physiology, and Immunology, University of Córdoba, Córdoba, 14004, Spain.; Reina Sofía University Hospital, Córdoba, 14004, Spain.; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain., Yubero-Serrano EM; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain.; Reina Sofía University Hospital, Córdoba, 14004, Spain.; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain.; Lipids and Atherosclerosis Unit, Reina Sofía University Hospital, Córdoba, Spain., López-Sánchez LM; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain.; Department of Cell Biology, Physiology, and Immunology, University of Córdoba, Córdoba, 14004, Spain.; Reina Sofía University Hospital, Córdoba, 14004, Spain.; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain., Romero-Martín S; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain.; Reina Sofía University Hospital, Córdoba, 14004, Spain.; Mammary Gland Unit, Reina Sofía University Hospital, Córdoba, Spain., Raya-Povedano JL; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain.; Reina Sofía University Hospital, Córdoba, 14004, Spain.; Mammary Gland Unit, Reina Sofía University Hospital, Córdoba, Spain., Álvarez-Benito M; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain.; Reina Sofía University Hospital, Córdoba, 14004, Spain.; Mammary Gland Unit, Reina Sofía University Hospital, Córdoba, Spain., Castaño JP; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain. justo@uco.es.; Department of Cell Biology, Physiology, and Immunology, University of Córdoba, Córdoba, 14004, Spain. justo@uco.es.; Reina Sofía University Hospital, Córdoba, 14004, Spain. justo@uco.es.; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain. justo@uco.es., Luque RM; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain. bc2luhur@uco.es.; Department of Cell Biology, Physiology, and Immunology, University of Córdoba, Córdoba, 14004, Spain. bc2luhur@uco.es.; Reina Sofía University Hospital, Córdoba, 14004, Spain. bc2luhur@uco.es.; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain. bc2luhur@uco.es., Gahete MD; Maimónides Institute of Biomedical Research of Córdoba (IMIBIC), IMIBIC building. Av. Menéndez Pidal s/n, Córdoba, 14004, Spain. bc2gaorm@uco.es.; Department of Cell Biology, Physiology, and Immunology, University of Córdoba, Córdoba, 14004, Spain. bc2gaorm@uco.es.; Reina Sofía University Hospital, Córdoba, 14004, Spain. bc2gaorm@uco.es.; CIBER Pathophysiology of Obesity and Nutrition (CIBERobn), Córdoba, 14004, Spain. bc2gaorm@uco.es.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 Dec 27; Vol. 82 (1), pp. 18. Date of Electronic Publication: 2024 Dec 27.

Clinical Utility of microRNAs in Exhaled Breath Condensate as Biomarkers for Lung Cancer.

Autor: Pérez-Sánchez C; Department of Medicine, School of Clinical Medicine, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0AW, UK.; Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, 14004 Córdoba, Spain., Barbarroja N; Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, 14004 Córdoba, Spain., Pantaleão LC; Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Welcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK., López-Sánchez LM; Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, 14004 Córdoba, Spain., Ozanne SE; Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Welcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 0QQ, UK., Jurado-Gámez B; Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, 14004 Córdoba, Spain., Aranda E; Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, 14004 Córdoba, Spain.; Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), 28029 Madrid, Spain., Lopez-Pedrera C; Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, 14004 Córdoba, Spain., Rodríguez-Ariza A; Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, 14004 Córdoba, Spain.; Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), 28029 Madrid, Spain.

Publikováno v: Journal of personalized medicine [J Pers Med] 2021 Feb 09; Vol. 11 (2). Date of Electronic Publication: 2021 Feb 09.

Nitric oxide and tumor metabolic reprogramming.

Autor: López-Sánchez LM; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Av. Menéndez Pidal s/n, E14004 Córdoba, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Av. Monforte de Lemos, 3-5, E 28029 Madrid, Spain., Aranda E; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Av. Menéndez Pidal s/n, E14004 Córdoba, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Av. Monforte de Lemos, 3-5, E 28029 Madrid, Spain; Unidad de Gestión Clínica de Oncología Médica, Hospital Reina Sofía, Universidad de Córdoba, Av. Menéndez Pidal s/n, E14004 Córdoba, Spain., Rodríguez-Ariza A; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Av. Menéndez Pidal s/n, E14004 Córdoba, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Av. Monforte de Lemos, 3-5, E 28029 Madrid, Spain; Unidad de Gestión Clínica de Oncología Médica, Hospital Reina Sofía, Universidad de Córdoba, Av. Menéndez Pidal s/n, E14004 Córdoba, Spain. Electronic address: antonio.rodriguez.exts@juntadeandalucia.es.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2020 Jun; Vol. 176, pp. 113769. Date of Electronic Publication: 2019 Dec 17.

A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer.

Autor: Peñarando J; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain., López-Sánchez LM; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Mena R; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain., Guil-Luna S; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain., Conde F; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Hernández V; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain., Toledano M; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain., Gudiño V; The Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Raponi M; The Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Billard C; The Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Villar C; Unidad de Gestión Clínica de Anatomía Patológica, Hospital Universitario Reina Sofía, Córdoba, Spain., Díaz C; Unidad de Gestión Clínica de Cirugía General y del Aparato Digestivo, Hospital Universitario Reina Sofía, Córdoba, Spain., Gómez-Barbadillo J; Unidad de Gestión Clínica de Cirugía General y del Aparato Digestivo, Hospital Universitario Reina Sofía, Córdoba, Spain., De la Haba-Rodríguez J; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Unidad de Gestión Clínica de Oncología Médica, Hospital Universitario Reina Sofía, Córdoba, Spain., Myant K; The Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Aranda E; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Unidad de Gestión Clínica de Oncología Médica, Hospital Universitario Reina Sofía, Córdoba, Spain., Rodríguez-Ariza A; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), 14004 Avda Menéndez Pidal s/n, Córdoba, Spain. antonio.rodriguez.exts@juntadeandalucia.es.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. antonio.rodriguez.exts@juntadeandalucia.es.; Unidad de Gestión Clínica de Oncología Médica, Hospital Universitario Reina Sofía, Córdoba, Spain. antonio.rodriguez.exts@juntadeandalucia.es.

Publikováno v: BMC biology [BMC Biol] 2018 Jan 10; Vol. 16 (1), pp. 3. Date of Electronic Publication: 2018 Jan 10.