C3′- cis-Substituted carboxycyclopropyl glycines as metabotropic glutamate 2/3 receptor agonists: Synthesis and SAR studies

Autor: González, Rosario, Collado, Iván, López de Uralde, Beatriz, Marcos, Alicia, Martín-Cabrejas, Luisa M., Pedregal, Concepción, Blanco-Urgoiti, Jaime, Pérez-Castells, Javier, Alejandro Fernández, M., Andis, Sherri L., Johnson, Bryan G., Wright, Rebecca A., Schoepp, Darryle D., Monn, James A.

Publikováno v: In Bioorganic & Medicinal Chemistry 2005 13(23):6556-6570

2-Alkoxydihydrocinnamates as PPAR agonists. Activity modulation by the incorporation of phenoxy substituents

Autor: Martín, José A. ^*, Brooks, Dawn A., Prieto, Lourdes, González, Rosario, Torrado, Alicia, Rojo, Isabel, López de Uralde, Beatriz, Lamas, Carlos, Ferritto, Rafael, Dolores Martín-Ortega, María, Agejas, Javier, Parra, Francisco, Rizzo, John R., Rhodes, Gary A., Robey, Roger L., Alt, Charles A., Wendel, Samuel R., Zhang, Tony Y., Reifel-Miller, Anne, Montrose-Rafizadeh, Chahrzad, Brozinick, Joseph T., Hawkins, Eric, Misener, Elizabeth A., Briere, Daniel A., Ardecky, Robert, Fraser, James D., Warshawsky, Alan M.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 2005 15(1):51-55

Design of potent and selective 2-aminobenzimidazole-based p38alpha MAP kinase inhibitors with excellent in vivo efficacy.

Autor: de Dios A; Eli Lilly and Co., Lilly S.A., Avenida de la Industria, 30, 28108 Alcobendas, Madrid, Spain. a.de_dios@lilly.com, Shih C, López de Uralde B, Sánchez C, del Prado M, Martín Cabrejas LM, Pleite S, Blanco-Urgoiti J, Lorite MJ, Nevill CR Jr, Bonjouklian R, York J, Vieth M, Wang Y, Magnus N, Campbell RM, Anderson BD, McCann DJ, Giera DD, Lee PA, Schultz RM, Li LC, Johnson LM, Wolos JA

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2005 Apr 07; Vol. 48 (7), pp. 2270-3.