Preparation of Amino Alcohols Condensed with Carbohydrates: Evaluation of Cytotoxicity and Inhibitory Effect on NO Production

Autor: Aline F. Taveira, Elaine F. C. Reis, Alyria Teixeira Dias, Mireille Le Hyaric, Lívia L. Alves, Tais A. Correa, Sandra B.R. Castro, Ana Paula Ferreira, Mara R.C. Couri, Mauro V. de Almeida, Caio César de Souza Alves

Publikováno v: Chemical Biology & Drug Design. 76:451-456

This work reports the preparation of several amino alcohols condensed with d-arabinose, d-glucose, and d-galactose derivatives. These compounds were evaluated in vitro for their cytotoxicity and ability to decrease nitric oxide production in J774A.1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9c5dbf70fae7d202724f4e2090c51b5
https://doi.org/10.1111/j.1747-0285.2010.01026.x

Preparation and antitubercular activities of alkylated amino alcohols and their glycosylated derivatives

Autor: Lívia L. Alves, Maria Aparecida de Souza, Mauro V. de Almeida, Maria C.S. Lourenço, Aline F. Taveira, Mireille Le Hyaric, Ana Paula Ferreira, Débora R. R. P. Araujo, Felipe R. C. Vicente, Elaine F. C. Reis

Publikováno v: Bioorganic & Medicinal Chemistry. 15:7789-7794

A series of N- and C-alkylated amino alcohols and of their protected galactopyranosyl derivatives was synthesized and evaluated for antitubercular activity. Five of these compounds displayed good activity, with a MIC below 12.5mug/mL. The presence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e23ae2f867b9111df6dd816d617facb
https://doi.org/10.1016/j.bmc.2007.08.045

Immunomodulatory effects and improved prognosis of experimental autoimmune encephalomyelitis after O-tetradecanoyl-genistein treatment

Autor: Lívia L. Alves, Maria Christina Marques Nogueira Castañon, Luciano Mazzoccoli, Caio César de Souza Alves, Celso O. R. Junior, Jacy Gameiro, Ana Paula Ferreira, Mauro V. de Almeida, Henrique Couto Teixeira, Sandra B.R. Castro, Nathália Stela Visoná de Figueiredo, Maria A. Juliano, Alyria Teixeira Dias, Felipe Pereira Mesquita

Publikováno v: International immunopharmacology. 12(2)

Experimental autoimmune encephalomyelitis (EAE) is a murine autoimmune disease used to study multiple sclerosis (MS), a human inflammatory demyelinating disease of the central nervous system. Genistein, an isoflavonoid phytoestrogenic compound found

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e05939637478fdf423321b48b9dfb1
https://pubmed.ncbi.nlm.nih.gov/22245971

Synthesis and immunosuppressive activity of lipophilic amino alcohols and diamines

Autor: Lívia L. Alves, Elaine F. C. Reis, Celso O. R. Junior, Mauro V. de Almeida, Ana Paula Ferreira

Publikováno v: Chemical biologydrug design. 72(6)

In this work, we report the preparation and evaluation of the in vitro and in vivo of the immunosuppressive activity of a series of lipophilic amino alcohols and diamines. All compounds were evaluated for inhibition of cell proliferation, cytotoxicit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e96c948b5935a8ca0f56bd9936fb00
https://pubmed.ncbi.nlm.nih.gov/19090927

Effect of Potato Starch Hydrogel:Glycerol Monostearate Oleogel Ratio on the Physico-Rheological Properties of Bigels.

Autor: Alves Barroso L; Department of Food Engineering and Technology, School of Food Engineering, University of Campinas (UNICAMP), Monteiro Lobato Street, 80, Campinas 13083-862, Brazil., Grossi Bovi Karatay G; Department of Food Engineering and Technology, School of Food Engineering, University of Campinas (UNICAMP), Monteiro Lobato Street, 80, Campinas 13083-862, Brazil., Dupas Hubinger M; Department of Food Engineering and Technology, School of Food Engineering, University of Campinas (UNICAMP), Monteiro Lobato Street, 80, Campinas 13083-862, Brazil.

Publikováno v: Gels (Basel, Switzerland) [Gels] 2022 Oct 26; Vol. 8 (11). Date of Electronic Publication: 2022 Oct 26.