Segurança e Eficácia da Terapia com Células-tronco Mesenquimais Derivadas do Tecido Adiposo para Cardiopatia Isquêmica: Revisão Sistemática

Autor: Fernando Rabioglio Giugni, Melina de Oliveira Valdo Giugni, Henrique Trombini Pinesi, Fabio Cetinic Habrum, Lígia Nasi Laranjeira, Erica Regina Ribeiro Sady, Erica Aranha Suzumura, Luis Henrique Wolff Gowdak, José Eduardo Krieger

Publikováno v: Arquivos Brasileiros de Cardiologia, Vol 121, Iss 9 (2024)

Resumo Fundamento A terapia celular utilizando células-tronco mesenquimais derivadas do tecido adiposo (ADSC, sigla em inglês) apresenta grande potencial como tratamento para doenças cardiovasculares. Objetivo Realizamos uma revisão sistemática

Externí odkaz: https://doaj.org/article/4592fc85ab0b4a6fa439869da2e8e049

A randomized clinical trial to evaluate the efficacy and safety of rivaroxaban in patients with bioprosthetic mitral valve and atrial fibrillation or flutter: Rationale and design of the RIVER trial

Autor: João Fernando Monteiro Ferreira, Ricardo Pavanello, Ibraim Pinto, Roque Aras Junior, Viviane Bezerra Campos, Fernando Antibas Atik, Tiago Luiz Luz Leiria, Alexandre Cabral Zilli, Carlos E B de Lima, Fábio Serra Silveira, Flávio Tarasoutchi, Conrado R Hoffmann-Filho, Diogo O Barreto, Cézar Eumann Mesas, Lucas P. Damiani, Ricardo D'Oliveira Vieira, Renato D. Lopes, Otavio Berwanger, Maria S M O Paiva, Margaret Assad Cavalcante, Dalton Bertolim Précoma, Hélio Penna Guimarães, Bruna S. Sampaio, Renato H Nakagawa, Adail Paixão Almeida, Roney Orismar Sampaio, João David de Souza Neto, José Francisco Kerr Saraiva, Paulo S A Kalil, Francisco H. Fonseca, Pedro Gabriel Melo de Barros e Silva, Flávia Kojima, Roberto Vito Ardito, Lígia Nasi Laranjeira, Fernando Augusto Marinho dos Santos Figueira, Rodrigo Patriota, Alexandre Biasi Cavalcanti, Jaime G A Maldonado, Milena Ribeiro Paixão, Juliana Yamashita Santos, Idelzuíta Leandro Liporace, Diana Lamprea, Carlos C. Magalhães, Fabio R Farias, Valdir Ambrósio Moisés

Publikováno v: American heart journal. 231

The efficacy and safety of rivaroxaban in patients with bioprosthetic mitral valves and atrial fibrillation or flutter remain uncertain. DESIGN: RIVER was an academic-led, multicenter, open-label, randomized, non-inferiority trial with blinded outcom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa92d42392b0d0a493783a96faeec5d7
https://pubmed.ncbi.nlm.nih.gov/33045224

Driving Pressure-limited Strategy for Patients with Acute Respiratory Distress Syndrome. A Pilot Randomized Clinical Trial

Autor: Israel Silva Maia, Wilson de Oliveira Filho, Denise M. Paisani, Eliana B Caser, Lucas P. Damiani, Bruno Guimarães Dantas, Marcelo Luz Pereira Romano, Lígia Nasi Laranjeira, Marcos C. Borges, Alexandre Biasi Cavalcanti, Josue Almeida Victorino, Marcelo B. P. Amato

Publikováno v: Annals of the American Thoracic Society

Rationale: Evidence from observational studies suggests that driving pressure is strongly associated with pulmonary injury and mortality, regardless of positive end-expiratory pressure (PEEP) level...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6674645274fabab00f3612a489f31360
https://pubmed.ncbi.nlm.nih.gov/32356695

Halofuginone for non-hospitalized adult patients with COVID-19 a multicenter, randomized placebo-controlled phase 2 trial. The HALOS trial.

Autor: Bruno Martins Tomazini, Lucas Tramujas, Fernando Azevedo Medrado, Samara Pinheiro do Carmo Gomes, Karina Leal Negrelli, Gabriela Souza Murinize, Renato Hideo Nakagawa Santos, Bruna Martins Pereira Vianna, Bruna Fornazieri Piotto, Thabata Silva Veiga, Bianca Rodrigues do Santos, Ana Clara Peneluppi Horak, Olivia Mora Cavalcante Lemos, Marcela de Almeida Lopes, Beatriz Baptista Olicheski, Diego Lurentt Campones, Luiz Angelo Alencar Peixoto, Aline Dos Anjos Chaves Basilio, Otavio Celso Eluf Gebara, Ana Tarina Alvarez Lopes, Humberto Saconato, Nanci Valeis, Tamiris Abait Miranda, Ligia Nasi Laranjeira, Eliana Vieira Santucci, Aaron Foster Carlin, Jeffrey David Esko, Phillip Leo Stephan Marie Gordts, Sotirios Tsimikas, Alexandre Biasi Cavalcanti

Publikováno v: PLoS ONE, Vol 19, Iss 2, p e0299197 (2024)

BackgroundHalofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent in vitro activity against SARS-CoV-2 virus. The safety and efficacy of halofuginone in Covid-19 patients has not been studied.MethodsWe conducted a phase I

Externí odkaz: https://doaj.org/article/8f9063cdddcc407b8037ccf8dcd06051

Comparison of Biological and Mechanical Prostheses for Heart Valve Surgery: A Systematic Review of Randomized Controlled Trials

Autor: Antonio Carlos de Camargo Carvalho, Lígia Nasi Laranjeira, Valdir Ambrósio Moisés, Otavio Berwanger, Erica Aranha Suzumura, Alexandre Biasi Cavalcanti, José Amalth do Espírito Santo, Angelo Amato Vincenzo de Paola, Anna Maria Buehler, Alberto Takeshi Kiyose

Publikováno v: Arquivos Brasileiros de Cardiologia, Volume: 112, Issue: 3, Pages: 292-301, Published: 07 JAN 2019
Arquivos Brasileiros de Cardiologia
Arquivos Brasileiros de Cardiologia, Iss 0 (2019)
Arquivos Brasileiros de Cardiologia v.112 n.3 2019
Sociedade Brasileira de Cardiologia (SBC)
instacron:SBC

Background: The choice of a mechanical (MP) or biological prosthesis (BP) for patients with valvular heart disease undergoing replacement is still not a consensus. Objective: We aimed to determine the clinical outcomes of MP or BP placement in those

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3e0e1d2647f62b9ce9dd7b928a326e
https://doi.org/10.5935/abc.20180272