Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lígia Morganti"'
Autor:
Luciana Regina Meireles, Angélica Moura Freixeira da Silva, Camila Aparecida Carvalho, Norival Kesper, Andrés Jimenez Galisteo Jr, Camila Pereira Soares, Danielle Bastos Araujo, Edison Luiz Durigon, Danielle Bruna Leal Oliveira, Lígia Morganti, Rosa Maria Chura-Chambi, Heitor Franco de Andrade Jr
Publikováno v:
Clinics, Vol 75 (2020)
OBJECTIVES: COVID-19 is a public health emergency of international concern whose detection in recovered asymptomatic patients is dependent on accurate diagnosis as it enables the estimation of the susceptibility of the population to the infection. Th
Externí odkaz:
https://doaj.org/article/7cc7a0a07f7a44649a6adcc15c2b3c48
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background Native-like secondary structures and biological activity have been described for proteins in inclusion bodies (IBs). Tertiary structure analysis, however, is hampered due to the necessity of mild solubilization conditions. Denatur
Externí odkaz:
https://doaj.org/article/569a5f395a174518b77e4fdb0f7477c4
Autor:
Daniella dos Santos Courrol, Cristiane Castilho Fernandes da Silva, Luan Gavião Prado, Rosa Maria Chura-Chambi, Ligia Morganti, Gisele Oliveira de Souza, Marcos Bryan Heinemann, Lourdes Isaac, Fernando Paiva Conte, Fernanda Calheta Vieira Portaro, Rodrigo Nunes Rodrigues-da-Silva, Angela Silva Barbosa
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Extracellular proteolytic enzymes are produced by a variety of pathogenic microorganisms, and contribute to host colonization by modulating virulence. Here, we present a first characterization of leptolysin, a Leptospira metalloprotease of the pappal
Externí odkaz:
https://doaj.org/article/5f3e9449c46e49a3a9fcf9065da85cae
Autor:
Marcelo Pires Amaral, Fernanda Caroline Coirada, Juliana de Souza Apostolico, Nádia Tomita, Edgar Ruz Fernandes, Higo Fernando Santos Souza, Rosa Maria Chura-Chambi, Ligia Morganti, Silvia Beatriz Boscardin, Daniela Santoro Rosa
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 23-31 (2021)
Chikungunya virus (CHIKV) is an arbovirus transmitted to humans mainly by the bite of infected Aedes aegypti and Aedes albopictus mosquitoes. CHIKV illness is characterized by fever and long-lasting arthritic symptoms, and in some cases it is a deadl
Externí odkaz:
https://doaj.org/article/2a28c1d908d043f48a19f1b2e989e109
Autor:
Rosa Maria Chura-Chambi, Alvaro Rossan de Brandão Prieto-da-Silva, Matheus Martins Di Lela, João Ezequiel Oliveira, Patricia Estima Antonia Abreu, Luciana Regina Meireles, Heitor Franco de Andrade Junior, Ligia Morganti
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0262591 (2022)
SARS-CoV-2 Nucleocapsid (N) is the most abundant viral protein expressed in host samples and is an important antigen for diagnosis. N is a 45 kDa protein that does not present disulfide bonds. Intending to avoid non-specific binding of SARS-CoV-2 N t
Externí odkaz:
https://doaj.org/article/54c24a8166f844b3bee7b20af9399d82
Autor:
Danielle D. Munhoz, Jessika C. A. Silva, Natalia C. Freitas, Leo K. Iwai, Karina A. Aires, Christiane Y. Ozaki, Cristiane S. Souza, Letícia B. Rocha, Miriam A. Silva, Izabella M. Henrique, Waldir P. Elias, Eneas Carvalho, Ligia Morganti, Rosa M. Chura-Chambi, Roxane M. F. Piazza
Publikováno v:
Microorganisms, Vol 10, Iss 6, p 1174 (2022)
Pil-fimbriae is a type IV pili member, which is a remarkably versatile component with a wide variety of functions, including motility, attachment to different surfaces, electrical conductance, DNA acquisition, and secretion of a broad range of struct
Externí odkaz:
https://doaj.org/article/a3117dd02e7f46be8e64499c4a2a42e1
Autor:
Cleide Mara Rosa da Silva, Rosa Maria Chura-Chambi, Lennon Ramos Pereira, Yraima Cordeiro, Luís Carlos de Souza Ferreira, Ligia Morganti
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Proteins in inclusion bodies (IBs) present native-like secondary structures. However, chaotropic agents at denaturing concentrations, which are widely used for IB solubilization and subsequent refolding, unfold these secondary str
Externí odkaz:
https://doaj.org/article/80bef607c3644fd2b2df75b027b9ae1d
Autor:
Rosa Maria Chura-Chambi, Cleide Mara Rosa da Silva, Lennon Ramos Pereira, Paolo Bartolini, Luis Carlos de Souza Ferreira, Ligia Morganti
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211162 (2019)
In this study we evaluated the association of high hydrostatic pressure (HHP) and alkaline pH as a minimally denaturing condition for the solubilization of inclusion bodies (IBs) generated by recombinant proteins expressed by Escherichia coli strains
Externí odkaz:
https://doaj.org/article/370b146afb764e54a517efba0c4b6052
Autor:
Rosa Maria Chura-Chambi, Tatiana Rodrigues Fraga, Ludmila Bezerra da Silva, Bruno Bernardi Yamamoto, Lourdes Isaac, Angela Silva Barbosa, Ligia Morganti
Publikováno v:
Biotechnology Reports, Vol 19, Iss , Pp - (2018)
Enzymes from the thermolysin family are crucial factors in the pathogenesis of several diseases caused by bacteria and are potential targets for therapeutic interventions. Thermolysin encoded by the gene LIC13322 of the causative agent of leptospiros
Externí odkaz:
https://doaj.org/article/360c7cc227fe4b49be9d966434db45d0
Publikováno v:
International Archives of Otorhinolaryngology, Vol 18, Iss 03, Pp 319-321 (2014)
Abstract Paranasal sinus mucoceles are benign cystic lesions, filled with mucus, occurring due to an obstruction of involved sinus ostium. They are indolent, locally expansive, and destructive. Surgical treatment must be performed and, when done at t
Externí odkaz:
https://doaj.org/article/13034ab2cb0e4f9f94701af1d622b01d