Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Lígia C. Gomes‐da‐Silva"'
Autor:
Catarina S. Lobo, Maria Inês P. Mendes, Diogo A. Pereira, Lígia C. Gomes-da-Silva, Luis G. Arnaut
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Photodynamic therapy (PDT) with redaporfin stimulates colon carcinoma (CT26), breast (4T1) and melanoma (B16F10) cells to display high levels of CD80 molecules on their surfaces. CD80 overexpression amplifies immunogenicity because it increa
Externí odkaz:
https://doaj.org/article/635aa666182f4a30a63368b89c5bd10f
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTPhotodynamic therapy (PDT) is a medical treatment used to target solid tumors, where the administration of a photosensitizing agent and light generate reactive oxygen species (ROS), thus resulting in strong oxidative stress that selectively d
Externí odkaz:
https://doaj.org/article/7e2aa04ec7e14a2388520f2161f8daf1
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
In September 2020, the Japanese government approved cetuximab saratolacan (previously known as RM-1929, commercial name: Akalux) for the treatment of unresectable locally advanced or recurrent head and neck cancer. Cetuximab saratolacan is a chemical
Externí odkaz:
https://doaj.org/article/09d8d3b21b044491aa6f61d78e8eaf29
Autor:
Piotr Gierlich, Ana I. Mata, Claire Donohoe, Rui M. M. Brito, Mathias O. Senge, Lígia C. Gomes-da-Silva
Publikováno v:
Molecules, Vol 25, Iss 22, p 5317 (2020)
Photodynamic therapy (PDT) is a promising cancer treatment which involves a photosensitizer (PS), light at a specific wavelength for PS activation and oxygen, which combine to elicit cell death. While the illumination required to activate a PS impart
Externí odkaz:
https://doaj.org/article/0ad80201f7f9406d86e9f27368424dd2
Autor:
Piotr Gierlich, Luís Rodrigues, Fábio A. Schaberle, Susan Callaghan, Lígia C. Gomes-da-Silva, Mathias O. Senge
Publikováno v:
Journal of Porphyrins and Phthalocyanines
BODIPYs have been extensively used for biological imaging owing to their high fluorescent quantum yields of stability toward photobleaching. In this work, zwitterionic groups were introduced into trimethoxyphenyl-BODIPY derivatives to improve their w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a89d9862be65d3c5bc3af3154bbcd6
https://doi.org/10.1142/s1088424622500328
https://doi.org/10.1142/s1088424622500328
Autor:
Claire Donohoe, Asterios Charisiadis, Sophie Maguire, Brendan Twamley, Fábio A. Schaberle, Lígia C. Gomes‐da‐Silva, Mathias O. Senge
Publikováno v:
European Journal of Organic Chemistry. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8e68348ffc95990115f3fbe4d5d1f5e
https://doi.org/10.1002/ejoc.202300270
https://doi.org/10.1002/ejoc.202300270
Publikováno v:
Journal of Porphyrins and Phthalocyanines. 26:527-532
Photodynamic therapy (PDT) is a multi-component therapy which relies on the delivery of a photosensitizer drug and light in the presence of oxygen to mediate a therapeutic anti-cancer or anti-microbial effect. As a multi-component therapy, a multidis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2303ef241c51a71d55fba07a1af9d0fc
https://doi.org/10.1142/s1088424622500250
https://doi.org/10.1142/s1088424622500250
Autor:
Claire Donohoe, Asterios Charisiadis, Sophie Maguire, Brendan Twamley, Fábio A. Schaberle, Lígia C. Gomes‐da‐Silva, Mathias O. Senge
Publikováno v:
European Journal of Organic Chemistry. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18aef81a017b5d8543659738fdaa5e30
https://doi.org/10.1002/ejoc.202201453
https://doi.org/10.1002/ejoc.202201453
Autor:
Catarina S. Lobo, Maria Inês P. Mendes, Lígia C. Gomes-da-Silva, Luis G. Arnaut, Diogo A. Pereira
Photodynamic therapy (PDT) with redaporfin stimulates colon carcinoma (CT26), breast (4T1) and melanoma (B16F10) cells to display high levels of CD80 molecules on their surfaces. CD80 overexpression amplifies immunogenicity because it increases same
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1779e208a1b891ecbe4819c0cf967246
https://doi.org/10.21203/rs.3.rs-2201462/v1
https://doi.org/10.21203/rs.3.rs-2201462/v1
Autor:
Claire Donohoe, Fábio A. Schaberle, Fábio M. S. Rodrigues, Nuno P. F. Gonçalves, Christopher J. Kingsbury, Mariette M. Pereira, Mathias O. Senge, Lígia C. Gomes-da-Silva, Luis G. Arnaut
Publikováno v:
Journal of the American Chemical Society
The intrinsic challenge of large molecules to cross the cell membrane and reach intracellular targets is a major obstacle for the development of new medicines. We report how rotation along a single C-C bond, between atropisomers of a drug in clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033e230d45cc0a397da59cdda5e307ab
https://pubmed.ncbi.nlm.nih.gov/35960892
https://pubmed.ncbi.nlm.nih.gov/35960892