Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Lício A Velloso"'
Autor:
Carlos Poblete Jara, Guilherme Nogueira, Joseane Morari, Thaís Paulino do Prado, Renan de Medeiros Bezerra, Lício A Velloso, William Velander, Eliana Pereira de Araújo
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281373 (2023)
Advances in wound treatment depend on the availability of animal models that reflect key aspects of human wound healing physiology. To this date, the accepted mouse models do not reflect defects in the healing process for chronic wounds that are asso
Externí odkaz:
https://doaj.org/article/2c8642b4bfa845f0870628cb0b065004
Autor:
Sandra Lucinei Balbo, Gabriela Moreira Soares, Joseane Morari, Antonio Machado Felisberto, Jean Franciesco Vettorazzi, Gabriela Alves Bronczek, Maria Lúcia Bonfleur, Everardo Magalhães Carneiro, Antonio Carlos Boschero, Lício Augusto Velloso
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 11, Pp 12633-12640 (2024)
The epidemic of obesity has increased worldwide and is associated with comorbidities such as diabetes and cardiovascular disease. In this context, strategies that modulate body weight and improve glycemic metabolism have increased, and bariatric surg
Externí odkaz:
https://doaj.org/article/19741b7958084c34ac43789a114477d3
Autor:
Maria H M Lima, Andréa M Caricilli, Lélia L de Abreu, Eliana P Araújo, Fabiana F Pelegrinelli, Ana C P Thirone, Daniela M Tsukumo, Ana Flávia M Pessoa, Marinilce F dos Santos, Maria A de Moraes, José B C Carvalheira, Lício A Velloso, Mario J A Saad
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36974 (2012)
Wound healing is impaired in diabetes mellitus, but the mechanisms involved in this process are virtually unknown. Proteins belonging to the insulin signaling pathway respond to insulin in the skin of rats.The purpose of this study was to investigate
Externí odkaz:
https://doaj.org/article/ff995adceeda4ee897ead84bcf90b6bf
Autor:
Eduardo R Ropelle, Marcelo B Flores, Dennys E Cintra, Guilherme Z Rocha, José R Pauli, Joseane Morari, Claudio T de Souza, Juliana C Moraes, Patrícia O Prada, Dioze Guadagnini, Rodrigo M Marin, Alexandre G Oliveira, Taize M Augusto, Hernandes F Carvalho, Lício A Velloso, Mario J A Saad, José B C Carvalheira
Publikováno v:
PLoS Biology, Vol 8, Iss 8, p e1000465 (2010)
Overnutrition caused by overeating is associated with insulin and leptin resistance through IKKbeta activation and endoplasmic reticulum (ER) stress in the hypothalamus. Here we show that physical exercise suppresses hyperphagia and associated hypoth
Externí odkaz:
https://doaj.org/article/b7aefd17028b4467b5236c482917b926
Autor:
Alessandra Girasol, Gabriela G Albuquerque, Eli Mansour, Eliana P Araújo, Giovanna Degasperi, Raphael G Denis, José B Carvalheira, Mário J Saad, Lício A Velloso
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7707 (2009)
BACKGROUND:Several effects of leptin in the immune system rely on its capacity to modulate cytokine expression and apoptosis in the thymus. Surprisingly, some of these effects are dependent on signal transduction through the IRS1/PI3-kinase, but not
Externí odkaz:
https://doaj.org/article/cb058041e12f41ee9c918a187483dc45
Autor:
Eduardo R Ropelle, Maria Fernanda A Fernandes, Marcelo B S Flores, Mirian Ueno, Silvana Rocco, Rodrigo Marin, Dennys E Cintra, Lício A Velloso, Kleber G Franchini, Mario J A Saad, José B C Carvalheira
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3856 (2008)
AMP-activated protein kinase (AMPK) and mammalian Target of Rapamycin (mTOR) are key regulators of cellular energy balance and of the effects of leptin on food intake. Acute exercise is associated with increased sensitivity to the effects of leptin o
Externí odkaz:
https://doaj.org/article/9230306289ba417694ae944bbe5c5572
Relationship Between Circulating MicroRNAs and Left Ventricular Hypertrophy in Hypertensive Patients
Autor:
Elisangela C. P. Lopes, Layde R. Paim, Luís F. R. S. Carvalho-Romano, Edmilson R. Marques, Eduarda O. Z. Minin, Camila F. L. Vegian, José A. Pio-Magalhães, Lício A. Velloso, Otavio R. Coelho-Filho, Andrei C. Sposito, José R. Matos-Souza, Wilson Nadruz, Roberto Schreiber
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveLeft ventricular hypertrophy (LVH) is a common complication of hypertension and microRNAs (miRNAs) are considered to play an important role in cardiac hypertrophy development. This study evaluated the relationship between circulating miRNAs
Externí odkaz:
https://doaj.org/article/20a80fbc5b5240c3a45c5e5c55e2970a
Autor:
Ludmilla David de Moura, Lígia N. M. Ribeiro, Fabíola V. de Carvalho, Gustavo H. Rodrigues da Silva, Priscila C. Lima Fernandes, Sérgio Q. Brunetto, Celso D. Ramos, Lício A. Velloso, Daniele R. de Araújo, Eneida de Paula
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1552 (2021)
Melanoma is the most aggressive skin carcinoma and nanotechnology can bring new options for its pharmacological treatment. Nanostructured lipid carriers (NLC) are ideal drug-delivery carriers for hydrophobic drugs, such as the antineoplastic docetaxe
Externí odkaz:
https://doaj.org/article/c6f9ea20f71b40aa8d6a939607307371
Autor:
Vitor Rosetto Muñoz, José Diego Botezelli, Rafael Calais Gaspar, Alisson L. da Rocha, Renan Fudoli Lins Vieira, Barbara Moreira Crisol, Renata Rosseto Braga, Matheus Brandemarte Severino, Susana Castelo Branco Ramos Nakandakari, Gabriel Calheiros Antunes, Sérgio Q. Brunetto, Celso D. Ramos, Lício Augusto Velloso, Fernando Moreira Simabuco, Leandro Pereira de Moura, Adelino Sanchez Ramos da Silva, Eduardo Rochete Ropelle, Dennys Esper Cintra, José Rodrigo Pauli
Publikováno v:
Cellular and Molecular Life Sciences. 80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cfa08514f0ef87dd263ddfe2ddf08aa
https://doi.org/10.1007/s00018-023-04771-2
https://doi.org/10.1007/s00018-023-04771-2
Autor:
Carla Roberta Peachazepi Moraes, Ivanio Teixeira Borba-Junior, Franciele De Lima, Jéssica Ribeiro Alves Silva, Bruna Bombassaro, André C. Palma, Eli Mansour, Lício Augusto Velloso, Fernanda Andrade Orsi, Fábio Trindade Maranhão Costa, Erich Vinicius De Paula
Publikováno v:
Frontiers in Physiology. 14
Endothelial barrier (EB) disruption contributes to acute lung injury in COVID-19, and levels of both VEGF-A and Ang-2, which are mediators of EB integrity, have been associated with COVID-19 severity. Here we explored the participation of additional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a412f866d3f97406495cf53a8eec1031
https://doi.org/10.3389/fphys.2023.1113968
https://doi.org/10.3389/fphys.2023.1113968