Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Léon Assogba"'
Autor:
Nadia Meddad-Bel Habich, Jean-Edouard Ombetta, Aazdine Lamouri, Françoise Heymans, Léon Assogba, Azali Ahamada-Himidi, Chang-Zhi Dong, Jean-Jacques Godfroid, Darina Aoun, Jack Huet, Latifa Boukli, Carine Mounier
Publikováno v:
European Journal of Medicinal Chemistry. 40:850-861
Starting from 4-tetradecyloxybenzamidine ( PMS815 ), a non-specific inhibitor of GI and GII PLA 2 s, we report in this work the discovery of the specificity through design, synthesis and structure–activity relationships studies of different kinds o
Autor:
Jean-Edouard Ombetta, Françoise Heymans, Chang-Zhi Dong, Jean-Jacques Godfroid, Léon Assogba, Estera Touboul, Catherine Redeuilh, Carine Binisti, Jack Huet, Carine Mounier
Publikováno v:
ChemInform. 33
1-Benzoyl-2-alkyl piperazines are strong inhibitors of Group I and II secreted PLA2s. An improvement of their activity was obtained by replacing the amide function by a sulfamide and by introduction of electrodonor substituents on the para position o
Autor:
Léon, Assogba, Azali, Ahamada-Himidi, Nadia Meddad-Bel, Habich, Darina, Aoun, Latifa, Boukli, France, Massicot, Carine M, Mounier, Jack, Huet, Aazdine, Lamouri, Jean-Edouard, Ombetta, Jean-Jacques, Godfroid, Chang-Zhi, Dong, Françoise, Heymans
Publikováno v:
European journal of medicinal chemistry. 40(9)
Starting from 4-tetradecyloxybenzamidine (PMS815), a non-specific inhibitor of GI and GII PLA2s, we report in this work the discovery of the specificity through design, synthesis and structure-activity relationships studies of different kinds of PMS8
Autor:
Chang-Zhi Dong, Jack Huet, Françoise Heymans, Léon Assogba, Catherine Redeuilh, Carine Mounier, Carine Binisti, Estera Touboul, Jean-Edouard Ombetta, Jean-Jacques Godfroid
Publikováno v:
European journal of medicinal chemistry. 36(10)
1-Benzoyl-2-alkyl piperazines are strong inhibitors of Group I and II secreted PLA2s. An improvement of their activity was obtained by replacing the amide function by a sulfamide and by introduction of electrodonor substituents on the para position o