Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Léo Houdebine"'
Autor:
Léo Houdebine, Domenico D’Amico, Jean Bastin, Farah Chali, Céline Desseille, Valentin Rumeau, Judy Soukkari, Carole Oudot, Thaïs Rouquet, Bruno Bariohay, Julien Roux, Delphine Sapaly, Laure Weill, Philippe Lopes, Fatima Djouadi, Cynthia Bezier, Frédéric Charbonnier, Olivier Biondi
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Spinal Muscular Atrophy (SMA), an autosomal recessive neurodegenerative disease characterized by the loss of spinal-cord motor-neurons, is caused by mutations on Survival-of-Motor Neuron (SMN)-1 gene. The expression of SMN2, a SMN1 gene copy, partial
Externí odkaz:
https://doaj.org/article/0b7e68d9487c4a4d90e01f37457cf285
Autor:
Céline Desseille, Séverine Deforges, Olivier Biondi, Léo Houdebine, Domenico D’amico, Antonin Lamazière, Cédric Caradeuc, Gildas Bertho, Gaëlle Bruneteau, Laure Weill, Jean Bastin, Fatima Djouadi, François Salachas, Philippe Lopes, Christophe Chanoine, Charbel Massaad, Frédéric Charbonnier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Amyotrophic Lateral Sclerosis is an adult-onset neurodegenerative disease characterized by the specific loss of motor neurons, leading to muscle paralysis and death. Although the cellular mechanisms underlying amyotrophic lateral sclerosis (ALS)-indu
Externí odkaz:
https://doaj.org/article/93e08f1473ec471cac23c066507b727c
Autor:
Domenico D'Amico, Olivier Biondi, Camille Januel, Cynthia Bezier, Delphine Sapaly, Zoé Clerc, Mirella El Khoury, Venkat Krishnan Sundaram, Léo Houdebine, Thibaut Josse, Bruno Della Gaspera, Cécile Martinat, Charbel Massaad, Laure Weill, Frédéric Charbonnier
Publikováno v:
Neuropathology and applied neurobiologyREFERENCES. 48(5)
Spinal muscular atrophy (SMA) is a neuromuscular disease caused by survival of motor neuron (SMN) deficiency that induces motor neuron (MN) degeneration and severe muscular atrophy. Gene therapies that increase SMN have proven their efficacy but not
Autor:
Domenico D’Amico, Laure Weill, Valentin Rumeau, Thaïs Rouquet, Bruno Bariohay, Farah Chali, Cynthia Bezier, Céline Desseille, Julien Roux, Philippe Lopes, Léo Houdebine, Carole Oudot, Frédéric Charbonnier, Delphine Sapaly, Jean Bastin, Olivier Biondi, Judy Soukkari, Fatima Djouadi
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Frontiers, 2019, 10, pp.1258. ⟨10.3389/fphys.2019.01258⟩
Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology, 2019, 10, pp.1258. ⟨10.3389/fphys.2019.01258⟩
Frontiers in Physiology, Frontiers, 2019, 10, pp.1258. ⟨10.3389/fphys.2019.01258⟩
Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology, 2019, 10, pp.1258. ⟨10.3389/fphys.2019.01258⟩
International audience; Spinal Muscular Atrophy (SMA), an autosomal recessive neurodegenerative disease characterized by the loss of spinal-cord motor-neurons, is caused by mutations on Survival-of-Motor Neuron (SMN)-1 gene. The expression of SMN2, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1322e110ebc3740027f4fa4c141044
https://www.hal.inserm.fr/inserm-02893893/document
https://www.hal.inserm.fr/inserm-02893893/document
Autor:
François Girardet, Léo Houdebine, Jean-François Bureau, Gwendoline Quérol, Olivier Biondi, Suzie Lefebvre, Kevinee Khoobarry, Delphine Sapaly, Anne-Sophie Armand, Christophe Chanoine, Frédéric Charbonnier, Philippe Burlet, Matthieu Dos Santos, Perrine Delers
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.2075. ⟨10.1038/s41598-018-20219-1⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports, 2018, 8 (1), pp.2075. ⟨10.1038/s41598-018-20219-1⟩
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.2075. ⟨10.1038/s41598-018-20219-1⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Scientific Reports, 2018, 8 (1), pp.2075. ⟨10.1038/s41598-018-20219-1⟩
International audience; The hereditary neurodegenerative disorder spinal muscular atrophy (SMA) is characterized by the loss of spinal cord motor neurons and skeletal muscle atrophy. SMA is caused by mutations of the survival motor neuron (SMN) gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2edbe65306c86fca81ae82b1e5743a3d
https://hal-pasteur.archives-ouvertes.fr/pasteur-02090360/file/s41598-018-20219-1.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-02090360/file/s41598-018-20219-1.pdf
Autor:
Thaïs Rouquet, Julien Branchu, Evelyne Benoit, Bruno Della Gaspera, Olivier Biondi, Bruno Bariohay, Christophe Chanoine, Claude Pariset, Farah Chali, Céline Desseille, Léo Houdebine, Philippe Lopes, Frédéric Charbonnier
Publikováno v:
The Journal of Physiology. 594:1931-1952
Key points The real impact of physical exercise parameters, i.e. intensity, type of contraction and solicited energetic metabolism, on neuroprotection in the specific context of neurodegeneration remains poorly explored. In this study behavioural, bi
Autor:
Léo Houdebine, Cristina Anna Gallelli, Nirmal Kumar Sampathkumar, Julien Grenier, Marialetizia Rastelli
Multiple sclerosis (MS) is a central nervous demyelinating disease characterized by cyclic loss and repair of myelin sheaths associated with chronic inflammation and neuronal loss. This degenerative pathology is accompanied by modified levels of oxys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c076448fa724ecbbcc62ba9b41b88fd
http://hdl.handle.net/11573/1122776
http://hdl.handle.net/11573/1122776
Autor:
Olivier, Biondi, Julien, Branchu, Amina, Ben Salah, Léo, Houdebine, Lise, Bertin, Farah, Chali, Céline, Desseille, Laure, Weill, Gabriel, Sanchez, Camille, Lancelin, Saba, Aïd, Philippe, Lopes, Claude, Pariset, Sylvie, Lécolle, Jocelyn, Côté, Martin, Holzenberger, Christophe, Chanoine, Charbel, Massaad, Frédéric, Charbonnier
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(34)
Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by the selective loss of spinal motor neurons due to the depletion of the survival of motor neuron (SMN) protein. No therapy is currently available for SMA, which represents the l