Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Léo Colmet-Daage"'
Autor:
Clémence Astier, Carine Ngo, Léo Colmet-Daage, Virginie Marty, Olivia Bawa, Claudio Nicotra, Maud Ngo-Camus, Antoine Italiano, Christophe Massard, Jean-Yves Scoazec, Cristina Smolenschi, Michel Ducreux, Antoine Hollebecque, Sophie Postel-Vinay
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-6 (2024)
Abstract Biliary tract cancers (BTCs) are heterogeneous malignancies with dismal prognosis due to tumor aggressiveness and poor response to limited current therapeutic options. Tumor exome profiling has allowed to successfully establish targeted ther
Externí odkaz:
https://doaj.org/article/0e99e403d1d04ae1bc389c998b7b3798
Autor:
Tiphaine Lambert, Cedric Pobel, Léo Colmet-Daage, Amélie Bigorgne, Brice RaubyY, Nicolas Sanchez-Escobar Aladro, Lucile Ter-MinassianN, Marie Kerisit, Aurélien Marabelle, Benjamin Besse, Antoine Hollebecque, Stéphane Champiat, Christophe Massard, Daphné Morel, Loic Velringue, Jean-Yves Scoazec
Publikováno v:
Cancer Treatment and Research Communications, Vol 32, Iss , Pp 100611- (2022)
PD-L1 and tumor-infiltrating lymphocytes play a key role in the immune escape of cancer, although their prognostic value remains unknown in patients with refractory solid cancer compared to other known prognostic estimation methods. In this ancillary
Externí odkaz:
https://doaj.org/article/95ce7b4936574ff9942662be50f5b474
Autor:
Sophie Postel-Vinay, Christopher J. Lord, Jessica A. Downs, Eric Deutsch, Jean-Charles Soria, Geneviève Almouzni, Jyoti S. Choudhary, Raphaël Margueron, Stephen J. Pettitt, Christophe Massard, Elaine Del Nery, Asha Konde, Clémence Astier, Asuka Kawai-Kawachi, Clémence Hénon, Samuel Jouny, Theodoros I. Roumeliotis, Suzanna R. Hopkins, Carine Ngo, Andrew Lamb, Cornelia Meisenberg, Marlène Garrido, Nicolas Dorvault, Ilirjana Bajrami, Léo Colmet-Daage, Thomas Eychenne, Daphné Morel, Roman M. Chabanon
Supplementary Figure from PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bfe75809eec04ce8fc0cb4e9b32f3e
https://doi.org/10.1158/0008-5472.22429915
https://doi.org/10.1158/0008-5472.22429915
Autor:
Sophie Postel-Vinay, Christopher J. Lord, Jessica A. Downs, Eric Deutsch, Jean-Charles Soria, Geneviève Almouzni, Jyoti S. Choudhary, Raphaël Margueron, Stephen J. Pettitt, Christophe Massard, Elaine Del Nery, Asha Konde, Clémence Astier, Asuka Kawai-Kawachi, Clémence Hénon, Samuel Jouny, Theodoros I. Roumeliotis, Suzanna R. Hopkins, Carine Ngo, Andrew Lamb, Cornelia Meisenberg, Marlène Garrido, Nicolas Dorvault, Ilirjana Bajrami, Léo Colmet-Daage, Thomas Eychenne, Daphné Morel, Roman M. Chabanon
Supplementary Table from PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91bf09169c717b744a215d84d8cf834
https://doi.org/10.1158/0008-5472.22429903.v1
https://doi.org/10.1158/0008-5472.22429903.v1
Autor:
Sophie Postel-Vinay, Christopher J. Lord, Jessica A. Downs, Eric Deutsch, Jean-Charles Soria, Geneviève Almouzni, Jyoti S. Choudhary, Raphaël Margueron, Stephen J. Pettitt, Christophe Massard, Elaine Del Nery, Asha Konde, Clémence Astier, Asuka Kawai-Kawachi, Clémence Hénon, Samuel Jouny, Theodoros I. Roumeliotis, Suzanna R. Hopkins, Carine Ngo, Andrew Lamb, Cornelia Meisenberg, Marlène Garrido, Nicolas Dorvault, Ilirjana Bajrami, Léo Colmet-Daage, Thomas Eychenne, Daphné Morel, Roman M. Chabanon
Supplementary data from PBRM1 Deficiency Confers Synthetic Lethality to DNA Repair Inhibitors in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09316697716760f7a1e87f0f4cf714ba
https://doi.org/10.1158/0008-5472.22429900
https://doi.org/10.1158/0008-5472.22429900
Autor:
Sophie Postel-Vinay, Christopher J. Lord, Jessica A. Downs, Eric Deutsch, Jean-Charles Soria, Geneviève Almouzni, Jyoti S. Choudhary, Raphaël Margueron, Stephen J. Pettitt, Christophe Massard, Elaine Del Nery, Asha Konde, Clémence Astier, Asuka Kawai-Kawachi, Clémence Hénon, Samuel Jouny, Theodoros I. Roumeliotis, Suzanna R. Hopkins, Carine Ngo, Andrew Lamb, Cornelia Meisenberg, Marlène Garrido, Nicolas Dorvault, Ilirjana Bajrami, Léo Colmet-Daage, Thomas Eychenne, Daphné Morel, Roman M. Chabanon
Inactivation of Polybromo 1 (PBRM1), a specific subunit of the PBAF chromatin remodeling complex, occurs frequently in cancer, including 40% of clear cell renal cell carcinomas (ccRCC). To identify novel therapeutic approaches to targeting PBRM1-defe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6091fc71a7c522b42ba404c337832524
https://doi.org/10.1158/0008-5472.c.6513481.v1
https://doi.org/10.1158/0008-5472.c.6513481.v1
Autor:
Sylvain Baulande, Virginie Raynal, Valérie Combaret, Gudrun Schleiermacher, Estelle Daudigeos-Dubus, Simon Durand, Angela Bellini, Léo Colmet-Daage, Isabelle Janoueix-Lerosey, Orphée Blanchard, Caroline Louis-Brennetot, Olivier Delattre, Cécile Pierre-Eugène, Olivier Mirabeau
Publikováno v:
Oncotarget
The ALK gene is a major oncogene of neuroblastoma cases exhibiting ALK activating mutations. Here, we characterized two neuroblastoma cell lines established from a stage 4 patient at diagnosis either from the primary tumor (PT) or from the bone marro
Autor:
Gaëlle Pierron, Nadège Corradini, Marion Gambart, Eve Lapouble, Valérie Combaret, Dominique Valteau-Couanet, Léo Colmet-Daage, Isabelle Janoueix-Lerosey, Mathieu Chicard, Jean Michon, Virginie Bernard, Adrien Danzon, Virginie Raynal, Gudrun Schleiermacher, Angela Bellini, Laura Le Roux, Olivier Delattre, Sylvain Baulande, Estelle Thebaud, Franck Bourdeaut, Jaydutt Bhalshankar, Caroline Louis-Brennetot, Julien Maslian Planchon, Anne-Sophie Defachelles, Nathalie Clément, Nadia Bessoltane‐Bentahar
Publikováno v:
International Journal of Cancer
In neuroblastoma (NB), genetic alterations in chromatin remodeling (CRGs) and epigenetic modifier genes (EMGs) have been described. We sought to determine their frequency and clinical impact. Whole exome (WES)/whole genome sequencing (WGS) data and t
Autor:
François Doz, Mathieu Chicard, Louise Galmiche-Rolland, Eve Lapouble, Georges Audry, Gaëlle Pierron, Dominique Berrebi, Pascale Philippe-Chomette, Gudrun Schleiermacher, Paul Fréneaux, Hervé Brisse, Léo Colmet-Daage, Sylvain Baulande, Nathalie Clément, Jean Michon, Olivier Delattre, Mylène Bohec, Adrien Danzon, Aurore Coulomb, Sabine Sarnacki, Irene Jiménez
Publikováno v:
International Journal of Cancer. 144:68-79
Circulating tumor DNA (ctDNA) is a powerful tool for the molecular characterization of cancer. The most frequent pediatric kidney tumors (KT) are Wilms' tumors (WT), but other diagnoses may occur. According to the SIOP strategy, in most countries ped
Autor:
Samuel Jouny, Sophie Postel-Vinay, Suzanna R. Hopkins, Clémence Hénon, Marlène Garrido, Andrew Lamb, Jessica A. Downs, Jyoti S. Choudhary, Raphaël Margueron, Nicolas Dorvault, Theodoros I. Roumeliotis, Roman M. Chabanon, Elaine Del Nery, Christophe Massard, Léo Colmet-Daage, Geneviève Almouzni, Stephen J. Pettitt, Cornelia Meisenberg, Daphné Morel, Ilirjana Bajrami, Asha Konde, Jean-Charles Soria, Clémence Astier, Eric Deutsch, Christopher J. Lord, Carine Ngo, Asuka Kawai-Kawachi, Thomas Eychenne
Publikováno v:
Cancer research. 81(11)
Inactivation of Polybromo 1 (PBRM1), a specific subunit of the PBAF chromatin remodeling complex, occurs frequently in cancer, including 40% of clear cell renal cell carcinomas (ccRCC). To identify novel therapeutic approaches to targeting PBRM1-defe