Výsledky vyhledávání - "Léa Rodrigues-Simioni"

Akademický článek

Presynaptic Activity of an Isolated Fraction from Rhinella schneideri Poison

Autor: Sandro Rostelato-Ferreira, Cháriston André Dal Belo, Pedro Ismael da Silva Junior, Stephen Hyslop, Léa Rodrigues-Simioni, Thomaz Augusto Alves Rocha-e-Silva

Publikováno v: Advanced Pharmaceutical Bulletin, Vol 8, Iss 3, Pp 517-522 (2018)

Purpose: Rhinella schneideri is a toad found in many regions of the South America. The poison of the glands has cardiotoxic effect in animals and neuromuscular effects in mice and avian preparation. The purpose of this work was to identify the toxin

Externí odkaz: https://doaj.org/article/2790089f888d4934958afb3f199000bd

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Neuromuscular Activity of Micrurus laticollaris (Squamata: Elapidae) Venom in Vitro

Autor: Alejandro Carbajal-Saucedo, Rafael Stuani Floriano, Cháriston André Dal Belo, Alejandro Olvera-Rodríguez, Alejandro Alagón, Léa Rodrigues-Simioni

Publikováno v: Toxins, Vol 6, Iss 1, Pp 359-370 (2014)

In this work, we have examined the neuromuscular activity of Micrurus laticollaris (Mexican coral snake) venom (MLV) in vertebrate isolated nerve-muscle preparations. In chick biventer cervicis preparations, the MLV induced an irreversible concentrat

Externí odkaz: https://doaj.org/article/81124b8ab67b40449815a1cbbd6d66b5

Zobrazit plný text záznamu

Akademický článek

Inhibition of Kv2.1 Potassium Channels by MiDCA1, A Pre-Synaptically Active PLA2-Type Toxin from Micrurus dumerilii carinicauda Coral Snake Venom

Autor: Niklas Schütter, Yuri Correia Barreto, Vitya Vardanyan, Sönke Hornig, Stephen Hyslop, Sérgio Marangoni, Léa Rodrigues-Simioni, Olaf Pongs, Cháriston André Dal Belo

Publikováno v: Toxins, Vol 11, Iss 6, p 335 (2019)

MiDCA1, a phospholipase A2 (PLA2) neurotoxin isolated from Micrurus dumerilii carinicauda coral snake venom, inhibited a major component of voltage-activated potassium (Kv) currents (41 ± 3% inhibition with 1 μM toxin) in mouse cultured dorsal root

Externí odkaz: https://doaj.org/article/71016df68b4f4dc0984c9567cd98919c

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Presynaptic Proteins as Markers of the Neurotoxic Activity of BmjeTX-I and BmjeTX-II Toxins from Bothrops marajoensis (Marajó Lancehead) Snake Venom

Autor: Antonio Lisboa, Rodolfo Melaré, Junia R. B. Franco, Carolina V. Bis, Marta Gracia, Luis A. Ponce-Soto, Sérgio Marangoni, Léa Rodrigues-Simioni, Maria Alice da Cruz-Höfling, Thalita Rocha

Publikováno v: Biochemistry Research International, Vol 2016 (2016)

Neuromuscular preparations exposed to B. marajoensis venom show increases in the frequency of miniature end-plate potentials and twitch tension facilitation followed by presynaptic neuromuscular paralysis, without evidences of muscle damage. Consider

Externí odkaz: https://doaj.org/article/f63aac162bfc4ea88916a1cb57b922d4

Zobrazit plný text záznamu

Akademický článek

Guanidine Affects Differentially the Twitch Response of Diaphragm, Extensor Digitorum Longus and Soleus Nerve-Muscle Preparations of Mice

Autor: Maria Alice da Cruz Höfling, Rosana Ferrari, Léa Rodrigues-Simioni

Publikováno v: Molecules, Vol 17, Iss 6, Pp 7503-7522 (2012)

Guanidine has been used with some success to treat myasthenia gravis and myasthenic syndrome because it increases acetylcholine release at nerve terminals through K+, Na+ and Ca2+ channels-involving mechanisms. Currently, guanidine derivatives have b

Externí odkaz: https://doaj.org/article/76b5cf2f706e45a3896c11a0bba54def

Zobrazit plný text záznamu

Akademický článek

Influência de anestésicos locais sobre o bloqueio neuromuscular produzido pelo rocurônio: ação da lidocaína e da mistura enantiomérica em excesso de 50% de bupivacaína na junção neuromuscular Influencia de anestésicos locales sobre el bloqueo neuromuscular producido por el rocuronio: acción de la lidocaína y de la mezcla enantiomérica en exceso de 50% de bupivacaína en la junción neuromuscular Influence of local anesthetics on the neuromuscular blockade produced by rocuronium: effects of lidocaine and 50% enantiomeric excess bupivacaine on the neuromuscular junction

Autor: Angélica de Fátima de Assunção Braga, Vanessa Henriques Carvalho, Franklin Sarmento da Silva Braga, Léa Rodrigues-Simioni, Yolanda Christina S Loyola, Glória Braga Potério

Publikováno v: Revista Brasileira de Anestesiologia, Vol 59, Iss 6, Pp 725-734 (2009)

JUSTIFICATIVA E OBJETIVOS: Os efeitos dos anestésicos locais (AL) na transmissão neuromuscular e sua influência no bloqueio neuromuscular produzido por bloqueadores neuromusculares competitivos são ainda alvo de pouca investigação. O objetivo d

Externí odkaz: https://doaj.org/article/c4d24653bafa48b4b2fc96fcbf8f6687

Zobrazit plný text záznamu

Akademický článek

Bp-13 PLA2: Purification and Neuromuscular Activity of a New Asp49 Toxin Isolated from Bothrops pauloensis Snake Venom

Autor: Georgina Sucasaca-Monzón, Priscila Randazzo-Moura, Thalita Rocha, Frank Denis Torres-Huaco, Augusto Vilca-Quispe, Luis Alberto Ponce-Soto, Sérgio Marangoni, Maria Alice da Cruz-Höfling, Léa Rodrigues-Simioni

Publikováno v: Biochemistry Research International, Vol 2015 (2015)

A new PLA2 (Bp-13) was purified from Bothrops pauloensis snake venom after a single chromatographic step of RP-HPLC on μ-Bondapak C-18. Amino acid analysis showed a high content of hydrophobic and basic amino acids and 14 half-cysteine residues. The

Externí odkaz: https://doaj.org/article/d08ef520bc2b43009ea15656a436990b

Zobrazit plný text záznamu

Akademický článek

Presynaptic neuromuscular action of a methanolic extract from the venom of Rhinella schneideri toad

Autor: Sandro Rostelato-Ferreira, Cháriston A Dal Belo, Gildo B Leite, Stephen Hyslop, Léa Rodrigues-Simioni

Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 20, Iss 0 (2014)

BackgroundRhinella schneideri, previously known as Bufo paracnemis, is a common toad in many regions of Brazil. Its venom exerts important cardiovascular effects on humans and other animals. Although this toad venom has been the subject of intense in

Externí odkaz: https://doaj.org/article/1679c6bdf4124f028e1275042b8eff70

Zobrazit plný text záznamu

Acción de la heparina y moduladores de acetilcolina en la neurotoxicidad del sapo Rhinella schneideri (Anura: Bufonidae) en Brasil

Autor: Rafael Stuani Floriano, Natália Tribuiani, Orlando Bozzoni Vettorazzo, Allan Pinto Leal, Yoko Oshima-Franco, Cháriston André Dal Belo, Léa Rodrigues-Simioni, Sandro Rostelato-Ferreira

Publikováno v: Revista de Biología Tropical; Vol. 69 No. 2 (2021): Revista de Biología Tropical (Rev. Biol. Trop.): Continuous publication, April-June 2021; 545-556
Revista de Biología Tropical; Vol. 69 Núm. 2 (2021): Revista de Biología Tropical (Rev. Biol. Trop.): Publicación continua, Abril-Junio 2021; 545-556
Revista Biología Tropical; Vol. 69 N.º 2 (2021): Revista de Biología Tropical (Rev. Biol. Trop.): Publicación continua, Abril-Junio 2021; 545-556
Portal de Revistas UCR
Universidad de Costa Rica
instacron:UCR
Revista de Biología Tropical, Volume: 69, Issue: 2, Pages: 545-556, Published: JUN 2021

Introduction: Rhinella schneideri is a toad widely distributed in South America and its poison is characterized by inducing cardiotoxicity and neurotoxicity. Objective: In this work, we investigated pharmacological strategies to attenuate the periphe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185067fb5001c53704e767ac72b0d81e
https://doi.org/10.15517/rbt.v69i2.44539

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání