Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Léa J. Becker"'
Autor:
Léa J. Becker, Clémentine Fillinger, Robin Waegaert, Sarah H. Journée, Pierre Hener, Beyza Ayazgok, Muris Humo, Meltem Karatas, Maxime Thouaye, Mithil Gaikwad, Laetitia Degiorgis, Marie des Neiges Santin, Mary Mondino, Michel Barrot, El Chérif Ibrahim, Gustavo Turecki, Raoul Belzeaux, Pierre Veinante, Laura A. Harsan, Sylvain Hugel, Pierre-Eric Lutz, Ipek Yalcin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract While depression and chronic pain are frequently comorbid, underlying neuronal circuits and their psychopathological relevance remain poorly defined. Here we show in mice that hyperactivity of the neuronal pathway linking the basolateral amy
Externí odkaz:
https://doaj.org/article/79edb28876214399bf2915cb6fdcd98c
Autor:
Dhanasak Dhanasobhon, Maria-Carmen Medrano, Léa J. Becker, Yunuen Moreno-Lopez, Sehrazat Kavraal, Charlotte Bichara, Rémy Schlichter, Perrine Inquimbert, Ipek Yalcin, Matilde Cordero-Erausquin
Publikováno v:
Neurobiology of Disease, Vol 155, Iss , Pp 105363- (2021)
Endogenous acetylcholine (ACh) is an important modulator of nociceptive sensory processing in the spinal cord. An increased level of spinal ACh induces analgesia both in humans and rodents while interfering with cholinergic signaling is allodynic, de
Externí odkaz:
https://doaj.org/article/a0a28af3ceee48c8ba41ff8ffd52d33b
Autor:
Makenzie R. Norris, John Bilbily, Léa J. Becker, Gustavo Borges, Yu-Hsuan Chang, Samantha S. Dunn, Manish K. Madasu, Ream Al-Hasani, Meaghan C. Creed, Jordan G. McCall
Neuropathic pain causes both sensory and emotional maladaptation. Preclinical animal studies of neuropathic pain-induced negative affect could result in novel insights into the mechanisms of chronic pain. Modeling pain-induced negative affect, howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea4cf32b7c3d0afeed34f18cc4c08773
https://doi.org/10.1101/2022.11.10.515959
https://doi.org/10.1101/2022.11.10.515959
Autor:
Léa J Becker, Clémentine Fillinger, Robin Waegaert, Pierre Hener, Beyza Ayazgok, Muris Humo, Sarah H Journée, Meltem Karatas, Laetitia Degiorgis, Marie des Neiges Santin, Mary Mondino, Michel Barrot, El Chérif Ibrahim, Gustavo Turecki, Raoul Belzeaux, Pierre Veinante, Laura A Harsan, Sylvain Hugel, Pierre-Eric Lutz, Ipek Yalcin
While depression and chronic pain are frequently comorbid, underlying neuronal circuits, and their relevance for the understanding of psychopathology, remain poorly defined. Here we show in mice that hyperactivity of the neuronal pathway linking the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::208c90ab4996acd0d348066196b9937d
https://doi.org/10.1101/2022.08.09.503276
https://doi.org/10.1101/2022.08.09.503276
Publikováno v:
European Journal of Neuroscience
European Journal of Neuroscience, Wiley, In press, ⟨10.1111/ejn.14686⟩
European Journal of Neuroscience, Wiley, In press, ⟨10.1111/ejn.14686⟩
International audience; Mood disorders such as depression and anxiety are frequently observed in patients suffering from chronic pain. Over time, different tests and models have been developed in rodents to study the anxiodepressive‐like consequenc
Autor:
Charlotte Bichara, Ipek Yalcin, Matilde Cordero-Erausquin, Maria-Carmen Medrano, Perrine Inquimbert, Sehrazat Kavraal, Dhanasak Dhanasobhon, Léa J. Becker, Rémy Schlichter, Yunuen Moreno-Lopez
Publikováno v:
Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2021, 155, pp.105363. ⟨10.1016/j.nbd.2021.105363⟩
Neurobiology of Disease, Vol 155, Iss, Pp 105363-(2021)
Neurobiology of Disease, Elsevier, 2021, 155, pp.105363. ⟨10.1016/j.nbd.2021.105363⟩
Neurobiology of Disease, Vol 155, Iss, Pp 105363-(2021)
Endogenous acetylcholine (ACh) is an important modulator of nociceptive sensory processing in the spinal cord. An increased level of spinal ACh induces analgesia both in humans and rodents while interfering with cholinergic signaling is allodynic, de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf275a88ffe3f8f22dfc0b45fda414f
https://hal.archives-ouvertes.fr/hal-03454164
https://hal.archives-ouvertes.fr/hal-03454164
Publikováno v:
Neuroscience & Biobehavioral Reviews
Neuroscience & Biobehavioral Reviews, Oxford: Elsevier Ltd., 2020, 115, pp.131-133. ⟨10.1016/j.neubiorev.2020.05.013⟩
Neuroscience & Biobehavioral Reviews, Oxford: Elsevier Ltd., 2020, 115, pp.131-133. ⟨10.1016/j.neubiorev.2020.05.013⟩
International audience
Autor:
Franck Mouthon, Nolwenn Couqueberg, Virginie Andry, Perrine Inquimbert, Quentin Leboulleux, Marine Droguerre, Baptiste Letellier, Pierre Hener, Michel Barrot, Ipek Yalcin, Mathieu Charvériat, Mélanie Kremer, Yannick Goumon, Elisabeth Waltisperger, Léa J. Becker
Publikováno v:
PAIN
PAIN, Elsevier, 2021, Publish Ahead of Print, ⟨10.1097/j.pain.0000000000002276⟩
PAIN, 2021, 162 (12), pp.2841-2853. ⟨10.1097/j.pain.0000000000002276⟩
Pain
PAIN, Elsevier, 2021, Publish Ahead of Print, ⟨10.1097/j.pain.0000000000002276⟩
PAIN, 2021, 162 (12), pp.2841-2853. ⟨10.1097/j.pain.0000000000002276⟩
Pain
Supplemental Digital Content is Available in the Text. Mefloquine/amitriptyline THN101 combination reduces cuff-induced neuropathic hypersensitivity by recruiting noradrenergic descending pathways and α2 adrenoceptors and by blocking connexin in mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24305fc7e1fa53636f828d27fe9f0761
https://hal.archives-ouvertes.fr/hal-03407798
https://hal.archives-ouvertes.fr/hal-03407798
Autor:
Beyza Ayazgök, Tomi Rantamäki, Elisabeth Waltisperger, Muris Humo, Léa J. Becker, Ipek Yalcin
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Elsevier, 2020, 100, pp.109898. ⟨10.1016/j.pnpbp.2020.109898⟩
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Elsevier, 2020, 100, pp.109898. ⟨10.1016/j.pnpbp.2020.109898⟩
International audience; Chronic pain produces psychologic distress, which often leads to mood disorders such as depression. Co-existing chronic pain and depression pose a serious socioeconomic burden and result in disability affecting millions indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca7d7a720b225bd79a79d814237e642
https://hal.archives-ouvertes.fr/hal-03001563/file/PNP_2020_accepted.pdf
https://hal.archives-ouvertes.fr/hal-03001563/file/PNP_2020_accepted.pdf
Autor:
Michel Barrot, Ipek Yalcin, François Daubeuf, Nelly Frossard, Frédéric Bihel, Martine Schmitt, Patrick Wagner, Jean-Jacques Bourguignon, Maud Bollenbach, Léa J. Becker, Baptiste Letellier, Adeline Obrecht, Muris Humo, Eric Salvat, Pascal Villa
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2018, 147, pp.163-182. ⟨10.1016/j.ejmech.2018.01.049⟩
European Journal of Medicinal Chemistry, Elsevier, 2018, 147, pp.163-182. ⟨10.1016/j.ejmech.2018.01.049⟩
4-phenylpyridin-2-yl-guanidine (5b): a new inhibitor of the overproduction of pro-inflammatory cytokines (TNFα and Il1β) was identified from a high-throughput screening of a chemical library on human peripheral blood mononuclear cells (PBMCs) after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff5ae2e3d53d5dcbce7ceeae4c559a8
https://hal.archives-ouvertes.fr/hal-02323729
https://hal.archives-ouvertes.fr/hal-02323729