Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Léa Guiet"'
Autor:
Aziz Yasri, Gwénaël Chevé, Pierre Warnault, Bénédicte Daydé-Cazals, Bénédicte Fauvel, Léa Guiet, Aurélia Spenlinhauer, Clémence Feneyrolles
Receptor tyrosine kinases (RTK) are transmembrane receptors that regulate signal transduction in cells. As a member of the TAM (Tyro-3, Axl, Mer) RTK subfamily, Axl regulates key processes such as cell growth, migration, aggregation, and apoptosis th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c06bf7fca29f6b519233af9391b1264
https://doi.org/10.1158/1535-7163.c.6536863.v1
https://doi.org/10.1158/1535-7163.c.6536863.v1
Autor:
Aziz Yasri, Gwénaël Chevé, Pierre Warnault, Bénédicte Daydé-Cazals, Bénédicte Fauvel, Léa Guiet, Aurélia Spenlinhauer, Clémence Feneyrolles
Supplementary data gathers supplementary table 1 and supplementary figure 1. Supplementary table 1: inhibition profile relationship for Axl related to sequence identity. Supplementary figure 1: structure of the described Axl's inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412ae6638e337beac55273f72077c584
https://doi.org/10.1158/1535-7163.22501681
https://doi.org/10.1158/1535-7163.22501681
Autor:
Gwénaël Chevé, Clémence Feneyrolles, Bénédicte Daydé-Cazals, Aurélia Spenlinhauer, Pierre Warnault, Léa Guiet, Bénédicte Fauvel, Aziz Yasri
Publikováno v:
Molecular Cancer Therapeutics. 13:2141-2148
Receptor tyrosine kinases (RTK) are transmembrane receptors that regulate signal transduction in cells. As a member of the TAM (Tyro-3, Axl, Mer) RTK subfamily, Axl regulates key processes such as cell growth, migration, aggregation, and apoptosis th
Publikováno v:
Thomas, S, Carter, T, Guiet, L, Frank, D & West, J 2013, ' Iron-Catalysed Reduction of Olefins using a Borohydride Reagent ', Advanced Synthesis & Catalysis, vol. 355, no. 5, pp. 880-884 . https://doi.org/10.1002/adsc.201200577
The iron-catalysed reduction of olefins has been achieved using a simple iron salt and sodium triethylborohydride. A wide range of mono- and trans-1,2-disubstituted alkenes have been reduced (91–100%) using 25 mol% iron(II) triflate, 1 mol% N-methy
Autor:
Gwénaël Chevé, Clémence Feneyrolles, Bénédicte Daydé-Cazals, Abdelaziz Yasri, Léa Guiet, Nathalie Van Hijfte, Bénédicte Fauvel, Mathilde Singer
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(4)
AXL is a receptor tyrosine kinase that plays a key role in tumor growth and proliferation. The scientific community has validated AXL as therapeutic target in the treatment of cancers for several years now, and several AXL inhibitors have been develo
Publikováno v:
RSC Advances. 3:25698
Operationally simple, iron-catalysed hydrogenation and reductive cross-coupling protocols have been developed using a bench-stable iron(II) pre-catalyst. The hydrogenation of 18 alkenes (50–99%) and reductive cross-coupling of vinyl halides with ar