Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Léa Cysne"'
Autor:
Juliana Figueiredo Peixoto, Luiz Filipe Gonçalves-Oliveira, Franklin Souza-Silva, Luzia Monteiro de Castro Côrtes, Léa Cysne Finkelstein, Geovane Dias-Lopes, Beatriz Ferreira de Carvalho Patricio, Carolina Guimarães de Souza Lima, Helvécio Vinícius Antunes Rocha, Fernando de Carvalho da Silva, Vitor Francisco Ferreira, Bernardo Acácio Santini Pereira, Carlos Roberto Alves
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 24, Iss , Pp 100525- (2024)
Leishmaniasis is a disease caused by Leishmania spp., affecting millions of people around the world. For decades, its treatment has been based on pentavalent antimonials, which notoriously cause toxic side effects in patients. In this study, epoxy-α
Externí odkaz:
https://doaj.org/article/3ba2ed1c14154a0b83c2d065ad65bb41
Autor:
Anabel Zabala-Peñafiel, Geovane Dias-Lopes, Léa Cysne-Finkelstein, Fátima Conceição-Silva, Luciana de Freitas Campos Miranda, Aline Fagundes, Armando de Oliveira Schubach, Maria Inês Fernandes Pimentel, Franklin Souza-Silva, Lucas de Almeida Machado, Carlos Roberto Alves
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Glucantime (SbV) is the first-line treatment against American Tegumentary Leishmaniasis. Resistance cases to this drug have been reported and related to host characteristics and parasite phenotypes. In this study, 12 Leishmania (Viannia) bra
Externí odkaz:
https://doaj.org/article/c189acbd39044fa790974bc4c3479a94
Autor:
Laura Barral-Veloso, Barbara Cristina de Albuquerque Melo, Raquel Santos-de-Souza, Léa Cysne-Finkelstein, Franklin Souza-Silva, Fernanda Nunes Santos, Joel Fontes de Sousa, Carlos Roberto Alves
Publikováno v:
Brazilian Journal of Infectious Diseases, Vol 24, Iss 3, Pp 201-207 (2020)
Cysteine proteinases are well-known virulence factors of Leishmania spp. with demonstrated actions in both experimental mouse infection and human infection. However, studies on these enzymes in canine leishmaniasis are scarce. Here, we show, for the
Externí odkaz:
https://doaj.org/article/cad710ab63da434e9096320019d7cb5d
Autor:
Daniel Ignacchiti Lacerda, Léa Cysne-Finkelstein, Marise Pinheiro Nunes, Paula Mello De-Luca, Marcelo da Silva Genestra, Leonor Laura Pinto Leon, Marcia Berrêdo-Pinho, Leila Mendonça-Lima, Denise Cristina de Souza Matos, Marco Alberto Medeiros, Sergio Coutinho Furtado de Mendonça
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 107, Iss 2, Pp 238-245 (2012)
In Leishmania amazonensis, kinetoplastid membrane protein-11 (KMP-11) expression increases during metacyclogenesis and is higher in amastigotes than in promastigotes, suggesting a role for this protein in the infection of the mammalian host. We show
Externí odkaz:
https://doaj.org/article/a8a2fc0207a740d98f845e1b1766ca87
Autor:
Denise CS Matos, Lanuza AP Faccioli, Léa Cysne-Finkelstein, Paula Mello De Luca, Suzana Corte-Real, Geraldo RG Armôa, Elezer Monte Blanco Lemes, Débora Decote-Ricardo, Sergio CF Mendonça
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 105, Iss 3, Pp 341-347 (2010)
Kinetoplastid membrane protein-11 (KMP-11), a protein present in all kinetoplastid protozoa, is considered a potential candidate for a leishmaniasis vaccine. A suitable leishmaniasis vaccine candidate molecule must be expressed in amastigotes, the in
Externí odkaz:
https://doaj.org/article/daa6780120964d63afaa0e9672585d3c
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Kinetoplastid membrane protein-11 (KMP-11), a protein present in all kinetoplastid protozoa, is considered a potential candidate for a leishmaniasis vaccine. In Leishmania amazonensis, KMP-11 is expressed in promastigotes and amastigotes. In both sta
Externí odkaz:
https://doaj.org/article/5bf56a593dfd44a3b501249dc622783b
Autor:
Peixoto, Juliana Figueiredo, Gonçalves-Oliveira, Luiz Filipe, Souza-Silva, Franklin, de Castro Côrtes, Luzia Monteiro, Finkelstein, Léa Cysne, Dias-Lopes, Geovane, Patricio, Beatriz Ferreira de Carvalho, Lima, Carolina Guimarães de Souza, Rocha, Helvécio Vinícius Antunes, da Silva, Fernando de Carvalho, Ferreira, Vitor Francisco, Pereira, Bernardo Acácio Santini, Alves, Carlos Roberto
Publikováno v:
In International Journal for Parasitology: Drugs and Drug Resistance April 2024 24
Akademický článek
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Autor:
Fátima Conceição-Silva, Regina Dórea, Claude Pirmez, A. O. Schubach, Léa Cysne, S. G. Coutinho
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 83, Pp 403-406 (1988)
Externí odkaz:
https://doaj.org/article/3aa25f6d53ca45a4ad23f2fe4a8b5d72
Autor:
Barbara Cristina de Albuquerque-Melo, Léa Cysne-Finkelstein, Luiz Filipe Gonçalves-Oliveira, Cynthia Machado Cascabulho, Andrea Henriques-Pons, Mirian Cláudia de Souza Pereira, Carlos Roberto Alves, Geovane Dias-Lopes
Publikováno v:
Parasitology. 149(12)
This study focuses on the role of the population structure of Leishmania spp. on the adaptive capacity of the parasite. Herein, we investigate the contribution of subpopulations of the L. (V.) braziliensis Thor strain (Thor03, Thor10 and Thor22) in t