Výsledky vyhledávání - "Léa Conchou"

Akademický článek

Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium

Autor: Léa Conchou, Bastien Doumèche, Frédéric Galisson, Sébastien Violot, Chloé Dugelay, Eric Diesis, Adeline Page, Anne-Lise Bienvenu, Stéphane Picot, Nushin Aghajari, Lionel Ballut

Publikováno v: Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)

Structural and functional analyses of yeast metacaspase reveal unique Ca2+ and Mg2+ binding sites and provide insights into Ca2+-dependent maturation of metacaspases along with the inhibitory effects of Mg2+ and Zn2+.

Externí odkaz: https://doaj.org/article/542560cbd5994992b4ca0f6218aa269e

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The Candida glabrata glycogen branching enzyme structure reveals unique features of branching enzymes of the Saccharomycetaceae phylum

Autor: Léa Conchou, Juliette Martin, Isabelle R Gonçalves, Frédéric Galisson, Sébastien Violot, Florence Guillière, Nushin Aghajari, Lionel Ballut

Publikováno v: Glycobiology. 32:343-355

Branching enzymes (BE) are responsible for the formation of branching points at the 1,6 position in glycogen and starch, by catalyzing the cleavage of α-1,4-linkages and the subsequent transfer by introducing α-1,6-linked glucose branched points. B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513ff069b33a2f5ab7a7d517ba63ab8d
https://doi.org/10.1093/glycob/cwab110

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Structural and molecular determinants of Candida glabrata metacaspase maturation and activation by calcium

Autor: Léa Conchou, Bastien Doumèche, Frédéric Galisson, Sébastien Violot, Chloé Dugelay, Eric Diesis, Adeline Page, Anne-Lise Bienvenu, Stéphane Picot, Nushin Aghajari, Lionel Ballut

Publikováno v: Communications biology. 5(1)

Metacaspases are caspase-like homologs which undergo a complex maturation process involving multiple intra-chain cleavages resulting in a composite enzyme made of a p10 and a p20 domain. Their proteolytic activity involving a cysteine-histidine catal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfba236de7577e0ca5341248583f5c39
https://pubmed.ncbi.nlm.nih.gov/36316540

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Exploring molecular determinants of polysaccharide lyase family 6–1 enzyme activity

Autor: Sébastien Violot, Vinesh Jugnarain, Loic Carrique, William Helbert, Nushin Aghajari, Lionel Ballut, Xavier Robert, Aurélien Thureau, Frédéric Galisson, Léa Conchou

Publikováno v: Glycobiology
Glycobiology, Oxford University Press (OUP), 2021, ⟨10.1093/glycob/cwab073⟩

The polysaccharide lyase family 6 (PL6) represents one of the 41 polysaccharide lyase families classified in the CAZy database with the vast majority of its members being alginate lyases grouped into three subfamilies, PL6_1–3. To decipher the mode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17a3c7540010134ffa9c00dca24d199
https://hal-cnrs.archives-ouvertes.fr/hal-03379698/file/Violotetal_Glycobiology_2021.pdf