Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Léa, Guyonnet"'
Autor:
Jos Urbanus, Jason Cosgrove, Joost B. Beltman, Yuval Elhanati, Rafael A. Moral, Cecile Conrad, Jeroen W. van Heijst, Emilie Tubeuf, Arno Velds, Lianne Kok, Candice Merle, Jens P. Magnusson, Léa Guyonnet, Jonas Frisén, Silvia Fre, Aleksandra M. Walczak, Thierry Mora, Heinz Jacobs, Ton N. Schumacher, Leïla Perié
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Ageing is associated with changes in the cellular composition of the immune system. During ageing, hematopoietic stem and progenitor cells (HSPCs) that produce immune cells are thought to decline in their regenerative capacity. However, HSPC
Externí odkaz:
https://doaj.org/article/59862cc7f88545bf963a5cd524bcd9f4
Autor:
Christophe, Peronino, Coralie L, Guerin, Peter, Ivak, Léa, Guyonnet, Richard, Chocron, Grégoire, Detriché, Christian, Latremouille, Maxime, Gruest, Aurélien, Philippe, Antoine, Capel, Yuri, Pya, Anne-Céline, Martin, Piet, Jansen, Nicolas, Gendron, Ivan, Netuka, David M, Smadja
Publikováno v:
ASAIO Journal. 68:e173-e178
The Aeson total artificial heart (A-TAH) has been developed for patients at risk of death from biventricular failure. We aimed to assess the inflammatory status in nine subjects implanted with the A-TAH in kinetics over one year. Laboratory assessmen
Autor:
Carole Henique, Guillaume Bollée, Xavier Loyer, Florian Grahammer, Neeraj Dhaun, Marine Camus, Julien Vernerey, Léa Guyonnet, François Gaillard, Hélène Lazareth, Charlotte Meyer, Imane Bensaada, Luc Legrès, Takashi Satoh, Shizuo Akira, Patrick Bruneval, Stefanie Dimmeler, Alain Tedgui, Alexandre Karras, Eric Thervet, Dominique Nochy, Tobias B. Huber, Laurent Mesnard, Olivia Lenoir, Pierre-Louis Tharaux
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Crescentic rapidly progressive glomerulonephritis is a severe form of glomerula disease characterized by podocyte proliferation and migration. Here Henique et al. demonstrate that inhibition of miRNA-92a prevents kidney failure by promoting the expre
Externí odkaz:
https://doaj.org/article/15231f9316144012af77e188917d3a47
Autor:
Antoine Capel, Ivan Netuka, Nicolas Gendron, Léa Guyonnet, Christophe Peronino, Piet G.M. Jansen, Lou Soret, David M. Smadja, Coralie L. Guerin, Christian Latremouille, Tristan Mirault, Grégoire Detriche, Alain Carpentier, Aurélien Philippe, Peter Ivak
Publikováno v:
Stem Cell Reviews and Reports. 17:2332-2337
The Aeson® total artificial heart (A-TAH) has been developed as a total heart replacement for patients at risk of death from biventricular failure. We previously described endothelialization of the hybrid membrane inside A-TAH probably at the origin
Autor:
Bérengère Koehl, Pierre Nivoit, Wassim El Nemer, Olivia Lenoir, Patricia Hermand, Catia Pereira, Valentine Brousse, Léa Guyonnet, Giulia Ghinatti, Malika Benkerrou, Yves Colin, Caroline Le Van Kim, Pierre-Louis Tharaux
Publikováno v:
Haematologica, Vol 102, Iss 7 (2017)
Although the primary origin of sickle cell disease is a hemoglobin disorder, many types of cells contribute considerably to the pathophysiology of the disease. The adhesion of neutrophils to activated endothelium is critical in the pathophysiology of
Externí odkaz:
https://doaj.org/article/6a3a0570186e4d42a0495ae850c6a600
Autor:
Hélène Lazareth, Olivia Lenoir, Sheerazed Boulkroun, Florian Garo, Angélique Derkx Rocha, Isabelle Giscos-Douriez, Léa Guyonnet, Marcus Johannes Möller, Carole Hénique, Maria-Christina Zennaro, Pierre-Louis Tharaux
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS We have recently demonstrated that targeting specific pathways in parietal epithelial cells (PEC) can markedly alleviate experimental extracapillary glomerular injury (1). Accumulating evidence has indicated the potential contribu
Autor:
Léa Guyonnet, grégoire Detriché, Nicolas Gendron, Aurélien Philippe, Christian Latremouille, Lou Soret, Antoine Capel, Christophe Peronino, Piet Jansen, Peter Ivak, Alain Carpentier, Tristan Mirault, Ivan Netuka, Coralie L Guerin, David Smadja
The Aeson® total artificial heart (A-TAH) has been developed as a total heart replacement for patients at risk of death from biventricular failure. We previously described endothelialization of the hybrid membrane inside A-TAH probably at the origin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2668f1101593817a870a0fce640f1f
https://doi.org/10.21203/rs.3.rs-905334/v1
https://doi.org/10.21203/rs.3.rs-905334/v1
Autor:
Laurie Soulat-Dufour, Alexandre Boissonnas, Giulia Chinetti, Florence Pinet, Ludivine Laurans, Fabien Lareyre, Andreas Giraud, Léa Guyonnet, Soraya Taleb, Bruno Esposito, Coralie L. Guerin, Marc Derive, Sylvie Lang, Juliette Raffort, José Vilar, Alain Tedgui, Marie Vandestienne, Jean-Sébastien Silvestre, Amir Boufenzer, Hafid Ait-Oufella, Ziad Mallat, Icía Santos-Zas, Rida Al-Rifai, Yujiao Zhang, Patrick Bruneval, Jérémie Joffre, Eric Clauser
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, 2021, 131 (2), pp.e142468. ⟨10.1172/JCI142468⟩
J Clin Invest
Journal of Clinical Investigation, 2021, 131 (2), pp.e142468. ⟨10.1172/JCI142468⟩
J Clin Invest
International audience; The triggering receptor expressed on myeloid cells 1 (TREM-1) drives inflammatory responses in several cardiovascular diseases but its role in abdominal aortic aneurysm (AAA) remains unknown. Our objective was to explore the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eec9b922594c68eee085f5d8a294f04
https://www.hal.inserm.fr/inserm-03833065
https://www.hal.inserm.fr/inserm-03833065
Autor:
Nicolas Gendron, Alain Carpentier, Adeline Blandinières, Olivier Sanchez, Lina Khider, Richard Chocron, Piet Jansen, Maria Konstantinou, Tristan Mirault, Christophe Peronino, Christian Latremouille, David M. Smadja, Dominique Revets, Anna Chipont, Benjamin Planquette, Antoine Capel, Markus Ollert, Audrey Cras, Camille Knosp, Benjamin Debuc, Léa Guyonnet, Guillaume Goudot, Jean Luc Diehl, Jeanne Rancic, Pascale Gaussem, Coralie L. Guerin
Publikováno v:
Stem Cell Reviews and Reports
Endothelial progenitor cells (EPCs) are involved in vasculogenesis and cardiovascular diseases. However, the phenotype of circulating EPCs remains elusive but they are more often described as CD34+KDR+. The aim of the study was to extensively charact
Autor:
Pierre-Louis Tharaux, Véronique Baudrie, Christophe Roubeix, Anna Chipont, Léa Guyonnet, Matthew A. Bailey, Tariq E. Farrah, Alicja Czopek, David C. Kluth, David J. Webb, Philippe Bonnin, Olivia Lenoir, Florian Sennlaub, Neeraj Dhaun
Publikováno v:
Kidney International
Kidney International, Nature Publishing Group, 2020, 98 (5), pp.1193-1209. ⟨10.1016/j.kint.2020.05.042⟩
Kidney International, 2020, 98 (5), pp.1193-1209. ⟨10.1016/j.kint.2020.05.042⟩
Kidney International, Nature Publishing Group, 2020, 98 (5), pp.1193-1209. ⟨10.1016/j.kint.2020.05.042⟩
Kidney International, 2020, 98 (5), pp.1193-1209. ⟨10.1016/j.kint.2020.05.042⟩
The endothelin system may be an important player in hypertensive end-organ injury as endothelin-1 increases blood pressure and is pro-inflammatory. The immune system is emerging as an important regulator of blood pressure and we have shown that the e