Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Léa, Darnaud"'
Autor:
Sandra Pinet, Stéphanie Durand, Alexandre Perani, Léa Darnaud, Fifame Amadjikpe, Mathieu Yon, Tiffany Darbas, Alain Vergnenegre, Thomas Egenod, Yannick Simonneau, Valérie Le Brun-Ly, Julia Pestre, Laurence Venat, Frédéric Thuillier, Alain Chaunavel, Mathilde Duchesne, Véronique Fermeaux, Anne Guyot, Sylvain Lacorre, Barbara Bessette, Fabrice Lalloué, Karine Durand, Elise Deluche
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundIn the context of personalized medicine, screening patients to identify targetable molecular alterations is essential for therapeutic decisions such as inclusion in clinical trials, early access to therapies, or compassionate treatment. The
Externí odkaz:
https://doaj.org/article/38353bee4b534532bc7e1714a16257c9
Autor:
Léa Darnaud, Clément Delage, Youssef Daali, Anne-Priscille Trouvin, Serge Perrot, Nihel Khoudour, Nadia Merise, Laurence Labat, Bruno Etain, Frank Bellivier, Célia Lloret-Linares, Vanessa Bloch, Emmanuel Curis, Xavier Declèves
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 979 (2023)
Drug-metabolizing enzymes and drug transporters are key determinants of drug pharmacokinetics and response. The cocktail-based cytochrome P450 (CYP) and drug transporter phenotyping approach consists in the administration of multiple CYP or transport
Externí odkaz:
https://doaj.org/article/bf3c6f60559b4662a7d219545910343c
Autor:
Perrine Courlet, Evelina Cardoso, Carole Bandiera, Athina Stravodimou, Jean-Philippe Zurcher, Haithem Chtioui, Isabella Locatelli, Laurent Arthur Decosterd, Léa Darnaud, Benoit Blanchet, Jérôme Alexandre, Anna Dorothea Wagner, Khalil Zaman, Marie Paule Schneider, Monia Guidi, Chantal Csajka
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1317 (2022)
Neutropenia is the most frequent dose-limiting toxicity reported in patients with metastatic breast cancer receiving palbociclib. The objective of this study was to investigate the pharmacokinetic–pharmacodynamic (PK/PD) relationships for toxicity
Externí odkaz:
https://doaj.org/article/74f52fb719014d18874ee81cbe9b0bad
Autor:
Léa Darnaud, Fabien Lamoureux, Cendrine Godet, Sandrine Pontier, Alexia Debard, Nicolas Venisse, Pauline Martins, Didier Concordet, Peggy Gandia
Publikováno v:
Drugs in R&D, Vol 18, Iss 4, Pp 317-321 (2018)
Abstract Background Isavuconazole is a new antifungal prodrug for the treatment of invasive aspergillosis and mucormycosis. As no clear pharmacokinetic-pharmacodynamic relationship has been established for patients, therapeutic drug monitoring is not
Externí odkaz:
https://doaj.org/article/e8262af5e4e142659e33e7d2a864af00
Autor:
Justine Lerat, Corinne Magdelaine, Anne‐Françoise Roux, Léa Darnaud, Hélène Beauvais‐Dzugan, Steven Naud, Laurence Richard, Paco Derouault, Karima Ghorab, Laurent Magy, Jean‐Michel Vallat, Pascal Cintas, Eric Bieth, Marie‐Christine Arne‐Bes, Cyril Goizet, Caroline Espil‐Taris, Hubert Journel, Annick Toutain, Jon Andoni Urtizberea, Odile Boespflug‐Tanguy, Fanny Laffargue, Philippe Corcia, Laurent Pasquier, Mélanie Fradin, Sylva Napuri, Jonathan Ciron, Jean‐Marc Boulesteix, Franck Sturtz, Anne‐Sophie Lia
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 9, Pp n/a-n/a (2019)
Abstract Background The most common inherited peripheral neuropathy is Charcot‐Marie‐Tooth disease (CMT), with a prevalence of 1/2500. Other symptoms can be associated to the condition, such as hearing loss. Currently, no global hearing impairmen
Externí odkaz:
https://doaj.org/article/fdb0f976071c48fd91636d29f0c9cf51
Publikováno v:
Therapies. 76:725-733
Resume La venlafaxine est le troisieme antidepresseur le plus frequemment prescrit en France la derniere decennie, avec environ 400 000 doses journalieres. Le suivi therapeutique pharmacologique (STP) de ce medicament, par mesure de la somme des comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02271b229049dd0b356206be83c9fb58
https://doi.org/10.1016/j.therap.2021.01.052
https://doi.org/10.1016/j.therap.2021.01.052
Autor:
Clément Delage, Léa Darnaud, Bruno Etain, Marina Vignes, Tu-Ky Ly, Alexia Frapsauce, Marc Veyrier, Marine Delavest, Emeline Marlinge, Vincent Hennion, Manon Meyrel, Aude Jacob, Margot Chouchana, Julie Smati, Guillaume Pataud, Nihel Khoudour, Jean-Eudes Fontan, Laurence Labat, Frank Bellivier, Célia Lloret-Linares, Xavier Declèves, Vanessa Bloch
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 11; Pages: 1869
Altered cytochromes P450 enzymes (CYP) and P-glycoprotein transporter (P-gp) activity may explain variabilities in drug response. In this study, we analyzed four years of phenotypic assessments of CYP/P-gp activities to optimize pharmacotherapy in ps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d488bcf8fd501470cdefa9df486b49e8
https://pubmed.ncbi.nlm.nih.gov/36579580
https://pubmed.ncbi.nlm.nih.gov/36579580
Publikováno v:
Therapie. 76(6)
Venlafaxine is the third most frequently prescribed antidepressant in France the last decade, with about 400,000 daily doses. Therapeutic drug monitoring (TDM) of this medication, by measuring the active moiety venlafaxine (V) and O-desmethylvenlafax
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7180925eca64309a4d78ce291faae867
https://pubmed.ncbi.nlm.nih.gov/33551091
https://pubmed.ncbi.nlm.nih.gov/33551091
Autor:
Hélène Beauvais-Dzugan, Paco Derouault, Laurent Pasquier, Corinne Magdelaine, Steven Naud, Anne-Françoise Roux, Laurent Magy, Odile Boespflug-Tanguy, Laurence Richard, Léa Darnaud, Jean-Marc Boulesteix, Anne-Sophie Lia, Caroline Espil-Taris, Cyril Goizet, Pascal Cintas, Marie-Christine Arne-Bes, Fanny Laffargue, Eric Bieth, Philippe Corcia, Mélanie Fradin, Franck Sturtz, Sylva Napuri, Jon Andoni Urtizberea, Hubert Journel, Karima Ghorab, Jean-Michel Vallat, Justine Lerat, Jonathan Ciron, Annick Toutain
Publikováno v:
Molecular Genetics & Genomic Medicine
Molecular Genetics & Genomic Medicine, Wiley Periodicals, Inc. 2019, 7 (9), ⟨10.1002/mgg3.839⟩
Molecular Genetics & Genomic Medicine, Vol 7, Iss 9, Pp n/a-n/a (2019)
Molecular Genetics & Genomic Medicine, Wiley Periodicals, Inc. 2019, 7 (9), pp.Université de Valence. ⟨10.1002/mgg3.839⟩
Molecular Genetics & Genomic Medicine, Wiley Periodicals, Inc. 2019, 7 (9), ⟨10.1002/mgg3.839⟩
Molecular Genetics & Genomic Medicine, Vol 7, Iss 9, Pp n/a-n/a (2019)
Molecular Genetics & Genomic Medicine, Wiley Periodicals, Inc. 2019, 7 (9), pp.Université de Valence. ⟨10.1002/mgg3.839⟩
International audience; Background: The most common inherited peripheral neuropathy is Charcot-Marie-Tooth disease (CMT), with a prevalence of 1/2500. Other symptoms can be associated to the condition, such as hearing loss. Currently, no global heari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b100302039594dae612285dfb5cb8a33
https://doi.org/10.1002/mgg3.839
https://doi.org/10.1002/mgg3.839
Autor:
Darnaud, Léa1 (AUTHOR), Delage, Clément2,3 (AUTHOR), Daali, Youssef4 (AUTHOR), Trouvin, Anne-Priscille5 (AUTHOR), Perrot, Serge5 (AUTHOR), Khoudour, Nihel1 (AUTHOR), Merise, Nadia1 (AUTHOR), Labat, Laurence2,6 (AUTHOR), Etain, Bruno2,7 (AUTHOR), Bellivier, Frank2,7 (AUTHOR), Lloret-Linares, Célia8 (AUTHOR), Bloch, Vanessa2,3 (AUTHOR), Curis, Emmanuel9,10 (AUTHOR), Declèves, Xavier1,2 (AUTHOR) xavier.decleves@u-paris.fr
Publikováno v:
Pharmaceutics. Mar2023, Vol. 15 Issue 3, p979. 25p.