Zobrazeno 1 - 10
of 12
pro vyhledávání: '"László Steiner"'
Autor:
Levente Kontra, Erik Czipa, Endre Barta, Mátyás Schiller, László Steiner, Orsolya Palne-Szen, Tibor Nagy, Júlia Koller
Publikováno v:
Database: The Journal of Biological Databases and Curation
ChIP-Seq reveals genomic regions where proteins, e.g. transcription factors (TFs) interact with DNA. A substantial fraction of these regions, however, do not contain the cognate binding site for the TF of interest. This phenomenon might be explained
Autor:
Almos Klekner, Tibor Hortobágyi, Gábor Zahuczki, László Bognár, József Virga, Éva Csősz, László Steiner, Judit Reményi-Puskár, Gábor Hutóczki, Gergő Kalló
Publikováno v:
Cancer Investigation. 36:492-503
Aim of the study: Astrocytomas are primary CNS malignancies which infiltrate the peritumoral tissue, even when they are low-grade. Schwannomas are also primary CNS tumors, however, they do not show peritumoral infiltration similarly to brain metastas
Autor:
Laszlo Nagy, László Steiner, Attila Horvath, Sascha Sauer, Gergely Nagy, Agnes Kriston, Zsuzsanna S. Nagy, Zsolt Czimmerer, Timea Silye-Cseh, Jean-François Deleuze, Bence Daniel, David Jonas
Publikováno v:
Molecular and Cellular Endocrinology. 471:63-74
Macrophages are able to differentiate into classically polarized (M1) or alternatively polarized (M2) states upon encountering pro-inflammatory cytokines such as interferon (IFN) γ or anti-inflammatory cytokines such as interleukin (IL) -4/IL-13, re
Autor:
Gábor Zahuczky, Gergő Kalló, Judit Tóth, Éva Csősz, Gábor Hutóczki, Tibor Hortobágyi, László Bognár, Almos Klekner, József Virga, László Steiner, Judit Reményi-Puskár
Publikováno v:
Journal of Neurological Surgery Part A: Central European Neurosurgery. 78:12-19
Background Glioblastoma multiforme (GBM) is the most common malignant disease of the central nervous system. Its prognosis is unfavorable, and the median overall survival of patients is 16 to 24 months. The main cause of the poor survival data are th
Autor:
Mate Kiss, Attila Horvath, Tamas Varga, Zsolt Czimmerer, Ixchelt Cuaranta-Monroy, Gergely Nagy, Laszlo Nagy, Nikolas Giannakis, Zsuzsanna Kolostyak, László Steiner, Szilárd Póliska, Bence Daniel
Publikováno v:
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms
MicroRNAs are important components of the post-transcriptional fine-tuning of macrophage gene expression in physiological and pathological conditions. However, the mechanistic underpinnings and the cis-acting genomic factors of how macrophage polariz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b501845ed0f737dfb48ddd99902ea07f
Autor:
Gergő Kalló, László Bognár, Almos Klekner, József Virga, Judit Reményi-Puskár, Éva Csősz, Gábor Hutóczki, Tibor Hortobágyi, László Steiner, Judit Tóth, Gábor Zahuczky
Peritumoral infiltration is characteristic of astrocytomas even in low-grade tumors. Tumor cells migrate to neighbouring tissue and cause recurrence. The extracellular matrix (ECM) plays a role in tumor invasion; expression levels of its components'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62dee8d248d75295419ac180adc98fc2
Autor:
Erik Czipa, Gergely Nagy, Endre Barta, Tibor Nagy, Laszlo Nagy, Sándor Pongor, László Steiner
Publikováno v:
BMC Genomics
Background ChIP-seq provides a wealth of information on the approximate location of DNA-binding proteins genome-wide. It is known that the targeted motifs in most cases can be found at the peak centers. A high resolution mapping of ChIP-seq peaks cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08f3e0c43a681702b835071ea623dc7
Autor:
Judit Tóth, Gergő Kalló, Almos Klekner, Judit Reményi-Puskár, László Bognár, József Virga, Beáta Scholtz, Tibor Hortobágyi, Éva Csősz, Gábor Hutóczki, László Steiner
Objective The effectiveness of therapy of intracerebral neoplasms is mainly influenced by the invasive behaviour of the tumour. The peritumoral invasion depends on the interaction between the tumour cells and the extracellular matrix (ECM) of the sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88baa8c4f01b45c2f372b17fb813341f
Autor:
Attila Horvath, Gábor Zahuczky, László Steiner, Bertalan Meskó, Károly Palatka, János Podani, Zoltán Szekanecz, Szilárd Póliska, Andrea Váncsa, and Laszlo Nagy, Zsolt Holló
Publikováno v:
Genome Medicine
Background: Biological therapies have been introduced for the treatment of chronic inflammatory diseases including rheumatoid arthritis (RA) and Crohn’s disease (CD). The efficacy of biologics differs from patient to patient. Moreover these therapi
Autor:
Zsolt Holló, Attila Horvath, Bertalan Meskó, János Podani, Zoltán Szekanecz, Gábor Zahuczky, Laszlo Nagy, László Steiner, Andrea Váncsa, Károly Palatka, Szilárd Póliska
Publikováno v:
Annals of the Rheumatic Diseases. 72:A55.1-A55
Background Biological therapies targeting tumour necrosis factor α (TNF-α) have been widely used to treat chronic inflammatory disorders including rheumatoid arthritis (RA) and Crohn’s disease (CD). As these treatment modalities are rather expens