Zobrazeno 1 - 10
of 193
pro vyhledávání: '"László Czirják"'
Untangling the relationship between smoking and systemic sclerosis: an analysis of the EUSTAR cohort
Autor:
Marco Matucci-Cerinic, Tom W J Huizinga, Paolo Airo, Jeska De Vries-Bouwstra, Elisabetta Zanatta, László Czirják, Piotr Wiland, Tatsuya Atsumi, Suzanne Cannegieter, Saad Ahmed, Gabriella Szücs, Francesco Ursini, Ina Koetter, Alexandra Balbir Gurman, Joerg C Henes, Jacopo Ciaffi, Sophie I E Liem, Eva M Hoekstra, EUSTAR Collaborators
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Objectives To untangle the association between smoking and systemic sclerosis (SSc).Methods In the European Scleroderma Trials and Research cohort, the autoantibody status was compared between ever-smokers and never-smokers. Time until disease progre
Externí odkaz:
https://doaj.org/article/f2427f3bbc774c75a3024c3f2b0e53c7
Autor:
Szabina Erdő-Bonyár, Judit Rapp, Rovéna Subicz, Kristóf Filipánits, Tünde Minier, Gábor Kumánovics, László Czirják, Tímea Berki, Diána Simon
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7933 (2024)
Type I interferon (IFN-I) signaling has been shown to be upregulated in systemic sclerosis (SSc). Dysregulated B-cell functions, including antigen presentation, as well as antibody and cytokine production, all of which may be affected by IFN-I signal
Externí odkaz:
https://doaj.org/article/e218d4bc75444d0eac43d858e4c04cc3
Autor:
Gabriella Nagy, Rucsandra Dobrota, Mike Oliver Becker, Tünde Minier, Cecília Varjú, Gábor Kumánovics, Oliver Distler, László Czirják
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background Systemic sclerosis (SSc) is a multi-organ disease with impaired health-related quality of life (HRQoL). The EULAR SSc Impact of Disease (ScleroID) is a newly introduced SSc-specific patient-reported outcome to evaluate HRQoL in SS
Externí odkaz:
https://doaj.org/article/29058f09c43a4cfdb4fbf86847332d55
Autor:
Vivien Vértes, Adél Porpáczy, Ágnes Nógrádi, Margit Tőkés-Füzesi, Máté Hajdu, László Czirják, András Komócsi, Réka Faludi
Publikováno v:
Cardiovascular Ultrasound, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Progressive cardiac fibrosis is the central aspect of the myocardial involvement in systemic sclerosis (SSc). We hypothesized that circulating biomarkers of the cardiac fibrosis may be useful in the early diagnosis of the cardiac
Externí odkaz:
https://doaj.org/article/0e691f27a6134c0bb8fd7bde2a51872f
Autor:
Pavel I Novikov, Thierry Martin, Eric Hachulla, Vanessa Smith, Maurizio Cutolo, Yannick Allanore, Camillo Ribi, Oliver Distler, Britta Maurer, Paolo Airo, Cosimo Bruni, Veronica Codullo, Luc Mouthon, Marie Vanthuyne, Elisabetta Zanatta, Simona Rednic, Ulf Müller-Ladner, Nemanja Damjanov, Anna-Maria Hoffmann-Vold, Michele Iudici, Suzana Jordan, Jean Sibilia, Mengtao Li, Roger Hesselstrand, Elise Siegert, László Czirják, Armando Gabrielli, Dominique Farge Bancel, Yolanda Braun-Moscovici, Nicolas Hunzelmann, Raffaele Pellerito, Jörg Henes, Bojana Stamenkovic, Carlo Francesco Selmi, Mohammed Tikly, Merete Engelhart, Valeria Riccieri, Cord Sunderkötter, Francesca Ingegnoli, Francesco Paolo Cantatore, Susanne Ullman, Maria Rosa Pozzi, Piotr Wiland, Juan Jose Alegre-Sancho, Brigitte Krummel-Lorenz, Ellen De Langhe, Branimir Anic, Carolina de Souza Müller, Simon Stebbings, Alessandra Vacca, Lisa Stamp, Kamal Solanki, Douglas Veale, Esthela Loyo, Edoardo Rosato, Cristina-Mihaela Tanaseanu, Rosario Foti, Codrina Ancuta, Ira Litinsky, Lesley Ann Saketkoo, Eduardo Kerzberg, Tim Schmeiser, Piercarlo Sarzi Puttini, Fabio Cacciapaglia, Marie-Elise Truchetet, Muriel Elhai, Juan José Alegre Sancho, Ivan Castellví, Serena Vettori, Vivien M Hsu, Masataka Kuwana, Sule Yavuz, Radim Becvar, Patricia E Carreira, Eugene J Kucharz, Bernard Coleiro, Paul Hasler, Carlos de la Puente, Svetlana Agachi, Thierry Zenone, Francesco Del Galdo, Doron Rimar, Alessandro Giollo, Lidia P Ananieva, Ina Kötter, Mislav Radic, Dominik Majewski, Kristine Herrmann, Goda Seskute, Lorinda S Chung, Laura Belloli, Ulrike Held, FJ López-Longo, Joerg H W Distler, Maria João Salvador, Simon Kuster, Klaus Steigmiller, Ana-Maria Gheorghiu, Katarzyna Romanowska-Prochnicka, Yuichiro Shirai, Chris Denton, Ruxandra M Ionescu, Stefan Heitmann Vera Ortiz-Santamaria, Walid Ahmed Abdel Atty Mohamed, Paloma Garcíadela Peña Lefebvre, Vera Bernardino
Publikováno v:
RMD Open, Vol 8, Iss 2 (2022)
Objectives Tocilizumab showed trends for improving skin fibrosis and prevented progression of lung fibrosis in systemic sclerosis (SSc) in randomised controlled clinical trials. We aimed to assess safety and effectiveness of tocilizumab in a real-lif
Externí odkaz:
https://doaj.org/article/b661f25cc59f441ea391bc0cb68007ab
Autor:
Viktória Csonka, Beáta Bódis, Dániel Kovács, Nelli Farkas, Endre Kálmán, László Czirják, Cecília Varjú
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Background Scleroedema adultorum of Buschke is a rare disorder characterized by fibromucinous thickening of the dermis that manifests mainly at the nape of the neck and on the upper back and shoulders. This study screened patients with diabe
Externí odkaz:
https://doaj.org/article/5c05b3fab3214133982cca37bf7927e3
Autor:
Yannick Allanore, Sylvie Bozzi, Augustin Terlinden, Doerte Huscher, Caroline Amand, Christina Soubrane, Elise Siegert, László Czirják, Patricia E. Carreira, Eric Hachulla, Elisabetta Zanatta, Mengtao Li, Paolo Airò, Fabian A. Mendoza, Edoardo Rosato, Oliver Distler, on behalf of the EUSTAR Collaborators
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-11 (2020)
Abstract Background Patients with diffuse cutaneous systemic sclerosis (dcSSc) have a poor prognosis. The importance of monitoring subjective measures of functioning and disability, such as the Health Assessment Questionnaire-Disability Index (HAQ-DI
Externí odkaz:
https://doaj.org/article/b0740c2493be40d498a6dc3efcc2210a
Autor:
Victoria P Werth, Ronald F van Vollenhoven, Laurent Arnaud, Ricard Cervera, Andrea Doria, Angela Tincani, Matthias Schneider, Marta Mosca, Nathalie Costedoat-Chalumeau, Cynthia Aranow, Michelle A Petri, Ian N Bruce, Dimitrios T Boumpas, Michael M Ward, Manuel Francisco Ugarte-Gil, Bernardo A Pons-Estel, Ann Elaine Clarke, Juanita Romero-Diaz, Caroline Gordon, Sang-Cheol Bae, Anisur Rahman, Murat Inanc, Søren Jacobsen, George Bertsias, Xavier Mariette, Thomas Dörner, Hendrika Bootsma, Josef Smolen, Mandana Nikpour, David Jayne, Martin Aringer, David Isenberg, László Czirják, Annegret Kuhn, Y K Onno Teng, Frédéric A Houssiau, Hermine Brunner, Eric Morand, Carlos Vasconcelos, Guillermo Pons-Estel, Graciela Alarcon, Eloisa Bonfa, Alexandre Voskuyl, Raquel Faria, Anne Voss, Maarten Limper, Anca D Askanase, Sandra Navarra, Cindy Coney, Ruth Fritsch-Stork, Bernadette van Leeuw, Michel Tsang-a-Sjoe, Rebecca Fischer, Marzena Helena Olesinska, Blanca Rubio, Yehuda Schoenfeld, Elena Zakharhova
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss 1 (2021)
Externí odkaz:
https://doaj.org/article/c4212b93061f4683be271e1376e1a0b4
Autor:
Diána Simon, Péter Balogh, Szabina Erdő-Bonyár, Katalin Böröcz, Tünde Minier, László Czirják, Tímea Berki
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Disease-associated, high-affinity pathological autoantibody production is a well-described consequence of immune dysregulation affecting B cells in systemic sclerosis (SSc), including the distribution of B-cell subsets. We have previously shown that
Externí odkaz:
https://doaj.org/article/eeb61859a4ed4b71a04a8993ff5f8160
Autor:
Szabina Erdő-Bonyár, Judit Rapp, Dávid Szinger, Tünde Minier, Gábor Kumánovics, László Czirják, Timea Berki, Diána Simon
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6777 (2022)
The phosphatidylinositol-3-kinase (PI3K)/Akt and the mammalian target of rapamycin (mTOR) pathways are known to play a key role in B-cell activation and fibrosis in systemic sclerosis (SSc). Receptors of B-cell activator factor (BAFF) utilize these p
Externí odkaz:
https://doaj.org/article/a7afce77f7394f35abdf9e64587366b5