Zobrazeno 1 - 10
of 27
pro vyhledávání: '"László, Grama"'
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186288 (2017)
Leiomodin proteins are vertebrate homologues of tropomodulin, having a role in the assembly and maintenance of muscle thin filaments. Leiomodin2 contains an N-terminal tropomodulin homolog fragment including tropomyosin-, and actin-binding sites, and
Externí odkaz:
https://doaj.org/article/71c79441e19643cca5410f20c578d3f9
Publikováno v:
The Protein Journal. 37:113-121
Hepcidin, the key hormone of iron homeostasis is responsible for lowering the serum iron level through its interaction with iron exporter ferroportin. Thus, hepcidin agonists provide a promising opportunity in the treatment of iron disorders caused b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917a507b4a3c8a5ab3c64b9524efa8d8
https://doi.org/10.1007/s10930-018-9759-9
https://doi.org/10.1007/s10930-018-9759-9
Cardiac leiomodin2 binds to the sides of actin filaments and regulates the ATPase activity of myosin
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186288 (2017)
PLoS ONE
PLoS ONE
Leiomodin proteins are vertebrate homologues of tropomodulin, having a role in the assembly and maintenance of muscle thin filaments. Leiomodin2 contains an N-terminal tropomodulin homolog fragment including tropomyosin-, and actin-binding sites, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c657585b31595950516c35ea59a60d
http://europepmc.org/articles/PMC5638494?pdf=render
http://europepmc.org/articles/PMC5638494?pdf=render
Autor:
György Sétáló, Attila Miseta, László Grama, Viktor S. Poór, Katalin Sipos, Edina Pandur, Zsuzsanna Fekete, Judit Nagy
Publikováno v:
Biochemical Journal. 451:301-311
Hepcidin is the major regulatory peptide hormone of iron metabolism, encoded by the HAMP (hepcidin antimicrobial peptide) gene. Hepcidin is expressed mainly in hepatocytes, but is also found in the blood in both a mature and prohormone form. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db188e41a102cc474aa4c1daf0d9b82
https://doi.org/10.1042/bj20121466
https://doi.org/10.1042/bj20121466
Publikováno v:
ChemPhysChem
ChemPhysChem, Wiley-VCH Verlag, 2016, pp.1329-40. ⟨10.1002/cphc.201501077⟩
ChemPhysChem, Wiley-VCH Verlag, 2016, pp.1329-40. 〈10.1002/cphc.201501077〉
ChemPhysChem, 2016, pp.1329-40. ⟨10.1002/cphc.201501077⟩
ChemPhysChem, Wiley-VCH Verlag, 2016, pp.1329-40. ⟨10.1002/cphc.201501077⟩
ChemPhysChem, Wiley-VCH Verlag, 2016, pp.1329-40. 〈10.1002/cphc.201501077〉
ChemPhysChem, 2016, pp.1329-40. ⟨10.1002/cphc.201501077⟩
International audience; DNA photolyases (PLs) and evolutionarily related cryptochrome (CRY) blue-light receptors form a widespread superfamily of flavoproteins involved in DNA photorepair and signaling functions. They share a flavin adenine dinucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c093713bd699bdcb51f170339efae32f
https://hal.archives-ouvertes.fr/hal-01457841
https://hal.archives-ouvertes.fr/hal-01457841
Autor:
Csaba Hetényi, László Grama, Botond Penke, Tamás Huber, Miklós S.Z. Kellermayer, Gusztáv Schay, Lívia Fülöp
Publikováno v:
Biophysical Journal. 103(7):1480-1489
The proline-, glutamate-, valine-, and lysine-rich (PEVK) domain of the giant muscle protein titin is thought to be an intrinsically unstructured random-coil segment. Various observations suggest, however, that the domain may not be completely devoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa79fd36c6fcb67d3a22c7b52a38745d
Autor:
Árpád Karsai, Attila Nagy, Botond Penke, Zs. Mártonfalvi, Miklós S.Z. Kellermayer, László Grama
Publikováno v:
Journal of Structural Biology. 155:316-326
The 39- to 42-residue-long amyloid beta-peptide (Abeta-peptide) forms filamentous structures in the neuritic plaques found in the neuropil of Alzheimer's disease patients. The assembly and deposition of Abeta-fibrils is one of the most important fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abec4e7ba82a5eb55b4e565b143f857
https://doi.org/10.1016/j.jsb.2005.12.015
https://doi.org/10.1016/j.jsb.2005.12.015
Autor:
Attila Nagy, Karoly Trombitás, Tamás Huber, Henk Granzier, László Grama, Miklós S.Z. Kellermayer, Pasquale Bianco
Publikováno v:
Biophysical Journal. 89:329-336
Titin is the main determinant of passive muscle force. Physiological extension of titin derives largely from its PEVK (Pro-Glu-Val-Lys) domain, which has a different length in different muscle types. Here we characterized the elasticity of the full-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146a01746ac98ba2ef1fcccdbddc4696
https://doi.org/10.1529/biophysj.104.057737
https://doi.org/10.1529/biophysj.104.057737
Autor:
András Kengyel, Attila Nagy, Paola Cacciafesta, Miklós S.Z. Kellermayer, László Grama, András Málnási-Csizmadia
Publikováno v:
Journal of Cell Science. 117:5781-5789
Parts of the PEVK (Pro-Glu-Val-Lys) domain of the skeletal muscle isoform of the giant intrasarcomeric protein titin have been shown to bind F-actin. However, the mechanisms and physiological function of this are poorly understood. To test for actin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d3cdace8e4bd1191a9de69124e43d5
https://doi.org/10.1242/jcs.01501
https://doi.org/10.1242/jcs.01501
Autor:
László Grama, Miklós S.Z. Kellermayer
Publikováno v:
Journal of Muscle Research and Cell Motility. 23:499-511
The details of the global and local structure and function of titin, a giant filamentous intrasarcomeric protein are largely undiscovered. Here we discuss a combination of bulk-solution and novel single-molecule techniques that may lend unique insigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77a3d85f92eeed0c56724321ccdc6299
https://doi.org/10.1023/a:1023414624092
https://doi.org/10.1023/a:1023414624092