Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Làszlò Tora"'
Autor:
Gizem Yayli, Andrea Bernardini, Paulina Karen Mendoza Sanchez, Elisabeth Scheer, Mylène Damilot, Karim Essabri, Bastien Morlet, Luc Negroni, Stéphane D. Vincent, H.T. Marc Timmers, László Tora
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113099- (2023)
Summary: To understand the function of multisubunit complexes, it is of key importance to uncover the precise mechanisms that guide their assembly. Nascent proteins can find and bind their interaction partners during their translation, leading to co-
Externí odkaz:
https://doaj.org/article/7c3160e0e5134daeb9335018d23b6679
Autor:
Marjorie Fournier, Amélie Rodrigue, Larissa Milano, Jean-Yves Bleuyard, Anthony M Couturier, Jacob Wall, Jessica Ellins, Svenja Hester, Stephen J Smerdon, László Tora, Jean-Yves Masson, Fumiko Esashi
Publikováno v:
eLife, Vol 11 (2022)
The tumour suppressor PALB2 stimulates RAD51-mediated homologous recombination (HR) repair of DNA damage, whilst its steady-state association with active genes protects these loci from replication stress. Here, we report that the lysine acetyltransfe
Externí odkaz:
https://doaj.org/article/5d62dc5a4b634c96b8938dd0c1b86dd9
Publikováno v:
Bio-Protocol, Vol 8, Iss 21 (2018)
The spatiotemporal localization of different intracellular factors in real-time and their detection in live cells are important parameters to understand dynamic protein-based processes. Therefore, there is a demand to perform live-cell imaging and to
Externí odkaz:
https://doaj.org/article/292f5b1ebd194922b1aa0eccb1c08e32
Autor:
Marjorie Fournier, László Tora
Publikováno v:
Molecular & Cellular Oncology, Vol 4, Iss 2 (2017)
We have recently identified the first human lysine (K) acetyltransferase 2A and 2B (called KAT2A/2B; known also as GCN5/PCAF, respectively)-dependent acetylome and revealed a mechanism by which KAT2A/2B-mediated acetylation of serine/threonine polo-l
Externí odkaz:
https://doaj.org/article/ec6964e0158c4803b495f44a677e95b3
Autor:
Yavor Hadzhiev, Haseeb K. Qureshi, Lucy Wheatley, Ledean Cooper, Aleksandra Jasiulewicz, Huy Van Nguyen, Joseph W. Wragg, Divyasree Poovathumkadavil, Sascha Conic, Sarah Bajan, Attila Sik, György Hutvàgner, Làszlò Tora, Agnieszka Gambus, John S. Fossey, Ferenc Müller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Transcription is globally repressed in early stage of embryo development, but a set of genes including pri-miR-430 and zinc finger genes is known to escape the repression. Here the authors image the very first transcriptional activities in the living
Externí odkaz:
https://doaj.org/article/c687a4f0c35544f7aae2b16326e305e8
Autor:
Kapil Gupta, Aleksandra A Watson, Tiago Baptista, Elisabeth Scheer, Anna L Chambers, Christine Koehler, Juan Zou, Ima Obong-Ebong, Eaazhisai Kandiah, Arturo Temblador, Adam Round, Eric Forest, Petr Man, Christoph Bieniossek, Ernest D Laue, Edward A Lemke, Juri Rappsilber, Carol V Robinson, Didier Devys, Làszlò Tora, Imre Berger
Publikováno v:
eLife, Vol 6 (2017)
General transcription factor TFIID is a key component of RNA polymerase II transcription initiation. Human TFIID is a megadalton-sized complex comprising TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). TBP binds to core promoter DNA,
Externí odkaz:
https://doaj.org/article/15058987fbdb49669a9c9076ca4ceb30
Autor:
Barbora Malecova, Alessandra Dall'Agnese, Luca Madaro, Sole Gatto, Paula Coutinho Toto, Sonia Albini, Tammy Ryan, Làszlò Tora, Pier Lorenzo Puri
Publikováno v:
eLife, Vol 5 (2016)
Change in the identity of the components of the transcription pre-initiation complex is proposed to control cell type-specific gene expression. Replacement of the canonical TFIID-TBP complex with TRF3/TBP2 was reported to be required for activation o
Externí odkaz:
https://doaj.org/article/cc4c05f27354405b9bad96eec246992b
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004483 (2014)
Faithful transcription of DNA is constantly threatened by different endogenous and environmental genotoxic effects. Transcription coupled repair (TCR) has been described to stop transcription and quickly remove DNA lesions from the transcribed strand
Externí odkaz:
https://doaj.org/article/391002d91f4243c39e17f890772d5747
Autor:
Sarina Ravens, Marjorie Fournier, Tao Ye, Matthieu Stierle, Doulaye Dembele, Virginie Chavant, Làszlò Tora
Publikováno v:
eLife, Vol 3 (2014)
The histone acetyltransferase (HAT) Mof is essential for mouse embryonic stem cell (mESC) pluripotency and early development. Mof is the enzymatic subunit of two different HAT complexes, MSL and NSL. The individual contribution of MSL and NSL to tran
Externí odkaz:
https://doaj.org/article/50aa5cc9a3c043beaeed83a4d7e20fc9
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38769 (2012)
Recent genome-wide chromatin immunoprecipitation coupled high throughput sequencing (ChIP-seq) analyses performed in various eukaryotic organisms, analysed RNA Polymerase II (Pol II) pausing around the transcription start sites of genes. In this stud
Externí odkaz:
https://doaj.org/article/58e7ca39af52435997af0374d7a3868d