Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Làszlò Tora"'
Autor:
Yavor Hadzhiev, Haseeb K. Qureshi, Lucy Wheatley, Ledean Cooper, Aleksandra Jasiulewicz, Huy Van Nguyen, Joseph W. Wragg, Divyasree Poovathumkadavil, Sascha Conic, Sarah Bajan, Attila Sik, György Hutvàgner, Làszlò Tora, Agnieszka Gambus, John S. Fossey, Ferenc Müller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Transcription is globally repressed in early stage of embryo development, but a set of genes including pri-miR-430 and zinc finger genes is known to escape the repression. Here the authors image the very first transcriptional activities in the living
Externí odkaz:
https://doaj.org/article/c687a4f0c35544f7aae2b16326e305e8
Autor:
Kapil Gupta, Aleksandra A Watson, Tiago Baptista, Elisabeth Scheer, Anna L Chambers, Christine Koehler, Juan Zou, Ima Obong-Ebong, Eaazhisai Kandiah, Arturo Temblador, Adam Round, Eric Forest, Petr Man, Christoph Bieniossek, Ernest D Laue, Edward A Lemke, Juri Rappsilber, Carol V Robinson, Didier Devys, Làszlò Tora, Imre Berger
Publikováno v:
eLife, Vol 6 (2017)
General transcription factor TFIID is a key component of RNA polymerase II transcription initiation. Human TFIID is a megadalton-sized complex comprising TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). TBP binds to core promoter DNA,
Externí odkaz:
https://doaj.org/article/15058987fbdb49669a9c9076ca4ceb30
Autor:
Barbora Malecova, Alessandra Dall'Agnese, Luca Madaro, Sole Gatto, Paula Coutinho Toto, Sonia Albini, Tammy Ryan, Làszlò Tora, Pier Lorenzo Puri
Publikováno v:
eLife, Vol 5 (2016)
Change in the identity of the components of the transcription pre-initiation complex is proposed to control cell type-specific gene expression. Replacement of the canonical TFIID-TBP complex with TRF3/TBP2 was reported to be required for activation o
Externí odkaz:
https://doaj.org/article/cc4c05f27354405b9bad96eec246992b
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004483 (2014)
Faithful transcription of DNA is constantly threatened by different endogenous and environmental genotoxic effects. Transcription coupled repair (TCR) has been described to stop transcription and quickly remove DNA lesions from the transcribed strand
Externí odkaz:
https://doaj.org/article/391002d91f4243c39e17f890772d5747
Autor:
Sarina Ravens, Marjorie Fournier, Tao Ye, Matthieu Stierle, Doulaye Dembele, Virginie Chavant, Làszlò Tora
Publikováno v:
eLife, Vol 3 (2014)
The histone acetyltransferase (HAT) Mof is essential for mouse embryonic stem cell (mESC) pluripotency and early development. Mof is the enzymatic subunit of two different HAT complexes, MSL and NSL. The individual contribution of MSL and NSL to tran
Externí odkaz:
https://doaj.org/article/50aa5cc9a3c043beaeed83a4d7e20fc9
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38769 (2012)
Recent genome-wide chromatin immunoprecipitation coupled high throughput sequencing (ChIP-seq) analyses performed in various eukaryotic organisms, analysed RNA Polymerase II (Pol II) pausing around the transcription start sites of genes. In this stud
Externí odkaz:
https://doaj.org/article/58e7ca39af52435997af0374d7a3868d
Autor:
Dominique Helmlinger, Sara Hardy, Gretta Abou-Sleymane, Adrien Eberlin, Aaron B Bowman, Anne Gansmüller, Serge Picaud, Huda Y Zoghbi, Yvon Trottier, Làszlò Tora, Didier Devys
Publikováno v:
PLoS Biology, Vol 4, Iss 3, p e67 (2006)
Spinocerebellar ataxia type 7 (SCA7) is one of several inherited neurodegenerative disorders caused by a polyglutamine (polyQ) expansion, but it is the only one in which the retina is affected. Increasing evidence suggests that transcriptional altera
Externí odkaz:
https://doaj.org/article/639ddf3c86644b5f81a8b449cf99f49c
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1150
Chromatin immunoprecipitation coupled high-throughput sequencing (ChIP-seq) is a common method to study in vivo protein-DNA interactions at the genome-wide level. The processing, analysis, and biological interpretation of gigabyte datasets, generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f2b8b3476fa67a2c38a9379106f5403
https://pubmed.ncbi.nlm.nih.gov/24743995
https://pubmed.ncbi.nlm.nih.gov/24743995
Autor:
H.Th. Marc Timmers, Làszlò Tora
Publikováno v:
Trends in Biochemical Sciences
Trends in Biochemical Sciences, Elsevier, 2005, 30 (1), pp.7-10. ⟨10.1016/j.tibs.2004.11.007⟩
Trends in Biochemical Sciences, Elsevier, 2005, 30 (1), pp.7-10. ⟨10.1016/j.tibs.2004.11.007⟩
International audience; Transcriptional regulation in eukaryotes is intimately coupled to chromatin dynamics. The SAGA (Spt-Ada-Gcn5) histone acetyltransferase (HAT) complex of Saccharomyces cerevisiae is a multi-subunit co-factor for RNA polymerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8630f30b1fd8c764a905771953a021
https://hal.archives-ouvertes.fr/hal-00187786
https://hal.archives-ouvertes.fr/hal-00187786
Autor:
Làszlò, Tora
Publikováno v:
Genesdevelopment. 16(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd6042432064e6c81cb56602e6c2b5ce
https://pubmed.ncbi.nlm.nih.gov/12066800
https://pubmed.ncbi.nlm.nih.gov/12066800