Zobrazeno 1 - 10
of 46
pro vyhledávání: '"L, Tripolitis"'
Publikováno v:
Research in Veterinary Science. 54:110-117
Muscle from horses with intermittent exercise associated rhabdomyolysis was examined to determine if calcium regulation was abnormal. In vitro studies on semimembranosus muscle fibre bundles showed the time to 50 per cent relaxation of caffeine-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::625e7659759f102bb42e2587874fea99
https://doi.org/10.1016/0034-5288(93)90019-c
https://doi.org/10.1016/0034-5288(93)90019-c
Publikováno v:
Toxicon. 31:43-51
The modulation of Ca 2+ release by a cardiotoxin (CTX) from Naja naja kaouthia snake venom was examined in terminal cisternae-containing fractions from equine and human skeletal muscle. Pretreatment with CTX (10 μM) decreased by 27% (human muscle),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9921978bb68b8fe198a78ad551d25f22
https://doi.org/10.1016/0041-0101(93)90355-m
https://doi.org/10.1016/0041-0101(93)90355-m
Publikováno v:
Muscle & Nerve. 15:932-936
The effects of phenytoin treatment were evaluated in 2 myotonic horses with hyperkalemic periodic paralysis (HPP). Phenytoin treatment abolished the clinical signs of muscle fasciculations following oral potassium challenge and decreased or abolished
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85292296b9bf3489315fdf2f53b63613
https://doi.org/10.1002/mus.880150811
https://doi.org/10.1002/mus.880150811
Publikováno v:
Life Sciences. 51:1731-1738
The modulation of Ca2+ release by synthetic bee venom melittin was examined in equine and human terminal cisternae-containing fractions. Melittin (0.1 microM) decreased the threshold of Ca(2+)-induced Ca2+ release by 20% in equine muscle and by 36% i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ae6c96d002405378bb6f1c6cb83f3f
https://doi.org/10.1016/0024-3205(92)90302-6
https://doi.org/10.1016/0024-3205(92)90302-6
Autor:
Susan Hanson, P. A. Conti, Jill Beech, Kirsten Erwin, Henry Rosenberg, L. Tripolitis, Jeffrey E. Fletcher
Publikováno v:
Biochemistry and Cell Biology. 68:1195-1201
Based on studies in swine, the malignant hyperthermia syndrome has been postulated to result from an enhanced sensitivity (low threshold) of the Ca2+-induced Ca2+-release process. However, fatty acid production is elevated in homogenates of skeletal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2bc513484fee66dce7afa86d9921a0
https://doi.org/10.1139/o90-177
https://doi.org/10.1139/o90-177
Publikováno v:
British journal of anaesthesia. 75(3)
Anaesthesia-induced malignant hyperthermia (MH) may be caused by specific gene defects in the skeletal muscle ryanodine receptor. We have studied the frequency of occurrence of the C1840T mutation, analogous to the porcine mutation, and three mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5664c7d262bd095eec573b6d4a0ae831
https://pubmed.ncbi.nlm.nih.gov/7547049
https://pubmed.ncbi.nlm.nih.gov/7547049
Publikováno v:
Research in veterinary science. 58(3)
The contractile activity, the threshold for calcium-induced calcium release in fractions of sarcoplasmic reticulum and the potassium concentration were determined in preparations of semimembranosus muscle from normal quarter horses and quarter horses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa3da9e35c3c91d5e02d66df462dcac
https://pubmed.ncbi.nlm.nih.gov/7659842
https://pubmed.ncbi.nlm.nih.gov/7659842
Publikováno v:
Biochemistry and molecular biology international. 29(4)
The temperature dependence of oleic acid-enhanced halothane- induced Ca2+ release and the existence of a reduced threshold of Ca(2+)-induced Ca2+ release were examined to determine their roles in human malignant hyperthermia. Halothane (8-11 mM) indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4317c3ddf05ea50f4cc3f68a8283d52c
https://pubmed.ncbi.nlm.nih.gov/7683948
https://pubmed.ncbi.nlm.nih.gov/7683948
Publikováno v:
Biochemistry international. 23(3)
Based on comparisons between Pietrain malignant hyperthermia susceptible swine and Yorkshire control swine, other investigators have reported a 3-fold lower Kd for [3H]ryanodine binding to terminal cisternae in the malignant hyperthermia swine. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e208474bc8b9752be09ff3f981a5e04
https://pubmed.ncbi.nlm.nih.gov/1877993
https://pubmed.ncbi.nlm.nih.gov/1877993
Autor:
Henry Rosenberg, L. Tripolitis, Scott Mayerberger, Michelle L. Yudkowsky, Jeffrey E. Fletcher
Publikováno v:
Life sciences. 49(22)
Malignant hyperthermia is caused by an abnormal increase in Ca 2+ levels in skeletal muscle in response to anesthetics, including halothane. Since fatty acid production is elevated in skeletal muscle from individuals with malignant hyperthermia, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8986ff5155b622b1731666ce070240d1
https://pubmed.ncbi.nlm.nih.gov/1943469
https://pubmed.ncbi.nlm.nih.gov/1943469