Zobrazeno 1 - 10
of 488
pro vyhledávání: '"L, Theilmann"'
Autor:
L. Rhiannon Hilton, Matthew T. Rätsep, M. Martin VandenBroek, Salema Jafri, Kimberly J. Laverty, Melissa Mitchell, Anne L. Theilmann, James A. Smart, Lindsey G. Hawke, Stephen D. Moore, Stephen J. Renaud, Michael J. Soares, Nicholas W. Morrell, Mark L. Ormiston
Publikováno v:
Hypertension. 79:2493-2504
Background: Natural killer (NK) cell impairment is a feature of pulmonary arterial hypertension (PAH) and contributes to vascular remodeling in animal models of disease. Although mutations in BMPR2 , the gene encoding the BMP (bone morphogenetic prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98544049ff5adf23b580ed6a7ef43152
https://doi.org/10.1161/hypertensionaha.122.19178
https://doi.org/10.1161/hypertensionaha.122.19178
Autor:
L. Rhiannon Hilton, Jodi L. MacKeil, Jeffrey Mewburn, Paula D. James, Devon V. Cole, Mark L. Ormiston, Donald H. Maurice, Anne L. Theilmann, Mara K.M. Whitford, Lindsey G. Hawke, Kimberly J. Dunham-Snary, Stephen L. Archer
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Pulmonary arterial hypertension is a disease of proliferative vascular occlusion that is strongly linked to mutations in BMPR2—the gene encoding the BMPR-II (BMP [bone morphogen
Objective: Pulmonary arterial hypertension is a disease of proliferative vascular occlusion that is strongly linked to mutations in BMPR2—the gene encoding the BMPR-II (BMP [bone morphogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270dc623528f30db6d6ebc25c01717fa
http://europepmc.org/articles/PMC7571847
http://europepmc.org/articles/PMC7571847
Autor:
Christopher J. Nicol, Donald H. Maurice, Jonah Burke-Kleinman, Paulina Brzezinska, Jodi L. MacKeil, Mark L. Ormiston, Anne L. Theilmann
Publikováno v:
Cellular signalling. 62
Recent reports show that protein kinase A (PKA), but not exchange protein activated by cAMP (EPAC), acts in a cell autonomous manner to constitutively reduce the angiogenic sprouting capacity of murine and human endothelial cells. Specificity in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef05f45d0a27048ab0ad37eb65ccb0d9
https://pubmed.ncbi.nlm.nih.gov/31176020
https://pubmed.ncbi.nlm.nih.gov/31176020
Autor:
Mark L. Ormiston, Anne L. Theilmann
Publikováno v:
The European respiratory journal. 53(6)
A new study identifies increases in the calcium activated chloride channel, TMEM16A, in the pulmonary arteries of IPAH patients and proposes the repurposing of benzbromarone, a non-specific inhibitor of the channel, as a novel therapy for the disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5734e980af13f325e6f77e7140735551
https://pubmed.ncbi.nlm.nih.gov/31023847
https://pubmed.ncbi.nlm.nih.gov/31023847
Autor:
Charles C.T. Hindmarch, François Potus, Jianhui Lin, Allan Lawrie, Zhi-Cheng Jing, Asish Dasgupta, Kimberly J. Dunham-Snary, Jennifer Fu, Stephen L. Archer, Danchen Wu, Jeffrey Mewburn, James Iremonger, Anne L. Theilmann, Sébastien Bonnet, Kuang-Hueih Chen, Mark L. Ormiston
Background:Mitotic fission is increased in pulmonary arterial hypertension (PAH), a hyperproliferative, apoptosis-resistant disease. The fission mediator dynamin-related protein 1 (Drp1) must complex with adaptor proteins to cause fission. Drp1-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a170809a421ce8e17fd2740bb9cae19
https://europepmc.org/articles/PMC6050130/
https://europepmc.org/articles/PMC6050130/
Publikováno v:
Surgical Case Reports
Hepatoid carcinoma (HC) is an extremely rare form of neoplasm. Its cellular structure resembles that of a hepatocellular carcinoma (HCC). To date, only 26 cases of hepatoid carcinoma of the pancreas have been reported in the literature. We report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddae222d55b0d4218af82938b165cfc
https://doi.org/10.1186/s40792-016-0197-7
https://doi.org/10.1186/s40792-016-0197-7
Publikováno v:
Animal Genetics. 20:257-266
Summary. Genomic DNAs from animals representing six breeds of cattle (Angus, Brahman, Hereford, Holstein, Jersey and Texas Longhorn) were screened with cloned gene probes in a search for restriction fragment length polymorphisms (RFLPs). Eleven RFLPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c7d1e96e2609cc6a5a1f2132481daf
https://doi.org/10.1111/j.1365-2052.1989.tb00866.x
https://doi.org/10.1111/j.1365-2052.1989.tb00866.x
Publikováno v:
Scopus-Elsevier
Summary. The genes encoding bovine prolactin and rhodopsin were assigned to syntenic groups on the basis of hybridization of DNA from a panel of bovine-hamster hybrid somatic cell lines with cloned prolactin and rhodopsin gene probes. Prolactin was f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa187b31c4954c2b08eaa3a7c5562f2
https://doi.org/10.1111/j.1365-2052.1988.tb00798.x
https://doi.org/10.1111/j.1365-2052.1988.tb00798.x
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 120:1426-1429
AIM OF STUDY Active immunization against hepatitis A having been undertaken in Germany since January 1993, a multicentre study was conducted to test, for the first time, immunogenicity of and tolerance to a candidate vaccine against hepatitis A and B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dca3ca25814aa36cdcfbdfdf8bbaf0a
https://doi.org/10.1055/s-2008-1055494
https://doi.org/10.1055/s-2008-1055494
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 120:1070-1073
Grundproblematik und Fragestellung: Die Hepatitis-C-Virusinfektion ist durch eine hohe Chronizitatsrate charakterisiert. Fur das HCV sind verschiedene Genotypen beschrieben, von denen die Verteilung in Deutschland nicht bekannt ist. Daher wurde die V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03e1fbf2eeb7bcab8998155d3cfc7f96
https://doi.org/10.1055/s-2008-1055446
https://doi.org/10.1055/s-2008-1055446