Zobrazeno 1 - 10
of 169
pro vyhledávání: '"L, Tammilehto"'
Autor:
Vuokko L. Kinnula, Tari Haahtela, L. Tammilehto, Henna Kupiainen, Ari Lindqvist, Tarja Laitinen, Maritta Kilpeläinen, Paula Kauppi
Publikováno v:
Journal of Asthma. 48:279-285
In clinical practice, patients whose airway disease shares features of both asthma and chronic obstructive pulmonary disease (COPD) remain poorly recognized.The study population consisted of 1546 patients with a diagnosis of asthma or COPD or both. B
Autor:
Hilkka Riihimäki, Riitta Riala, Ari Kaukiainen, Rami Martikainen, L. Tammilehto, Kari Reijula
Publikováno v:
International Archives of Occupational and Environmental Health. 78:452-458
Objective: To study the self-reported prevalence of respiratory symptoms and diseases among construction painters and estimate the potential risk for this group compared with a representative group of carpenters sharing the construction work environm
Autor:
Kirsti Husgafvel-Pursiainen, Harri Vainio, Sakari Knuutila, Antti Karjalainen, Karin Mattson, L. Tammilehto, Sisko Anttila, A.-M. Björkqvist
Publikováno v:
Genes, Chromosomes and Cancer. 22:79-82
We performed a comparative genomic hybridization study on 25 samples of adenocarcinoma and 19 samples of squamous cell carcinoma of the lung to detect recurrent changes in the genetic material. DNA copy number changes were found in 16 squamous cell c
Autor:
Stig Nordling, Sakari Knuutila, L. Tammilehto, A.-M. Björkqvist, Sisko Anttila, M Nurminen, Karin Mattson
Publikováno v:
British Journal of Cancer
The differential diagnosis of mesothelioma, primary adenocarcinomas and pleural metastases frequently causes problems. We have used the comparative genomic hybridization (CGH) technique on 34 malignant mesotheliomas and 30 primary lung carcinomas (ad
Publikováno v:
Scandinavian Journal of Work, Environment & Health. 23:266-270
Objectives The study analyzed the recent trend in the incidence of mesothelioma in Finland and evaluated the coverage of reporting work-related mesothelioma. Methods The incidence of mesothelioma in 1960--1995 was retrieved from the Finnish Cancer Re
Publikováno v:
Occupational and Environmental Medicine. 54:452-455
OBJECTIVES: Hairdressers are exposed to many irritative and allergenic substances capable of causing occupational respiratory symptoms and diseases. The self reported prevalence of respiratory symptoms and diseases was studied, and the risks among ha
Publikováno v:
British Journal of Cancer
Comparative genomic hybridization (CGH) analyses were performed on 27 human pleural mesothelioma tumour specimens, consisting of 18 frozen tumours and nine paraffin-embedded tumours, to screen for gains and losses of DNA sequences. Copy number change
Publikováno v:
British Journal of Cancer
Prior analysis of 20 human mesothelioma cell lines for p53 status revealed only two mutations and one p53 null cell line, although p53 expression was detected in most cell lines. In addition, mRNA and protein expression of the retinoblastoma gene pro
Autor:
Paula Kivipensas, A.-M. Björkqvist, L. Tammilehto, Kaija Linnainmaa, Katarina Pelin, Ritva Karhu, Olli-Pekka Kallioniemi, Karin Mattson, Sakari Knuutila
Publikováno v:
Cancer Genetics and Cytogenetics. 89:7-13
The molecular basis of malignant mesothelioma is poorly known. We examined genetic changes in 11 mesothelioma specimens by comparative genomic hybridization (CGH). Five DNA specimens originated from uncultured tumor tissues and six from cell lines es
Autor:
L. Tammilehto
Publikováno v:
Lung Cancer. 8:175-184
We have prospectively studied 98 patients with histologically confirmed mesothelioma in order to increase our knowledge of the biology of mesothelioma and to assess clinical characteristics, asbestos exposure and S-phase fraction as prognostic factor