Zobrazeno 1 - 10
of 1 353
pro vyhledávání: '"L, Stárka"'
Publikováno v:
Physiol Res
Through their receptors at each level of hypothalamo-pituitary-gonadal axis glucocorticoid excess, either endogenous or administered or stress-induced, could affect steroid production in the testis and thus male fertility. The main ways by which gluc
Publikováno v:
Physiol Res
Anthropogenic environmental pollutants affect many physiological, biochemical, and endocrine actions as reproduction, metabolism, immunity, behavior and as such can interfere with any aspect of hormone action. Microbiota and their genes, microbiome,
Publikováno v:
Physiol Res
Starling’s original definition of a hormone from 1905 was “a hormone is a substance produced by glands with internal secretion, which serve to carry signals through the blood to target organs”. Today, this definition is understood to be lacking
Akademický článek
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Publikováno v:
Physiological Research. :429-436
Twelve neuroactive and neuroprotective steroids, androgens and androgen precursors i.e. 3alpha,17beta-dihydroxy-5alpha-androstane, 3alpha-hydroxy-5alpha-androstan-17-one, 3alpha-hydroxy-5beta-androstan-17-one, androst-5-ene-3beta,17beta-diol, 3beta,1
Autor:
Antonín Pařízek, Martin Hill, L. Stárka, Milan Meloun, Oldrich Lapcik, Radmila Kancheva, Tomas Fait, Helena Havlíková, David Cibula, Vladimír Pouzar, J Sulcová, M Bičíková, Richard Hampl, J Klak
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 82:241-250
Five 3beta-hydroxy-5-ene steroids involved in the metabolic route from pregnenolone sulfate to dehydroepiandrosterone and its sulfate, of which three are known allosteric modulators of neurotransmitter receptors, were monitored in the serum of 20 wom
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:2225-2231
Epitestosterone has been demonstrated to act at various levels as a weak antiandrogen. So far, its serum levels have been followed up only in males. Epitestosterone and its major circulating precursor pregnenolone sulfate and T were measured in serum
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 86:297-299
Specific binding of [5,6-3H2]-17 beta-hydroxy-4,5-secoandrostan-3-one (or [3H]-4,5-secodihydrotestosterone, IX) to rat prostate cytosol receptors was observed and confirmed by two independent methods: by adsorption to dextran-charcoal and by polyacry
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 96:325-327
11 beta-Hydroxyandrostene-3,17-dione (11 beta-hydroxyandrostenedione), a potential marker for prenatal diagnosis of CAH, has been for the first time determined in amniotic fluid obtained from 68 women who later delivered children without endocrine di
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 55:405-408
Epitestosterone has for a long time been considered as a biologically inactive steroid. However, recently a distinct antiandrogenic activity of this naturally occurring endogenous epimer of testosterone has been demonstrated. Epitestosterone plays a