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pro vyhledávání: '"L, Spitalny"'
Akademický článek
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Publikováno v:
Delivery Strategies for Antisense Oligonucleotide Therapeutics ISBN: 9781315150901
Delivery Strategies for Antisense Oligonucleotide Therapeutics
Delivery Strategies for Antisense Oligonucleotide Therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83b0112c9796fb18a596ab3f42b76994
https://doi.org/10.1201/9781315150901-17
https://doi.org/10.1201/9781315150901-17
Publikováno v:
Applied Thermal Engineering. 71:838-846
In order to reduce the impact of the anthropogenic climate effect, the transition to a highly efficient and sustainable energy system is needed. In particular, the heating sector shows a large potential for efficiency measures. Besides increasing req
Autor:
Giovanni D'Alia, Michelle Clagett, Nehal Mohamed, Linda L. Nardone, Michael C. Babin, Steven M. Pincus, Juan Li, Leslie S. Casey, George L. Spitalny, Steven J.M. Jones
Publikováno v:
Infection and Immunity. 73:795-802
We have developed a therapeutic for the treatment of anthrax using an affinity-enhanced monoclonal antibody (ETI-204) to protective antigen (PA), which is the central cell-binding component of the anthrax exotoxins. ETI-204 administered preexposure b
Autor:
Claudia S. Ferreira, Nehal Mohamed, Leslie S. Casey, Arthur M. Friedlander, George L. Spitalny, Stephen F. Little, Juan Li
Publikováno v:
Infection and Immunity. 72:3276-3283
We investigated the ability of using monoclonal antibodies (MAbs) against anthrax protective antigen (PA), an anthrax exotoxin component, to modulate exotoxin cytotoxic activity on target macrophage cell lines. Anthrax PA plays a critical role in the
Akademický článek
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Autor:
Josaih Adaelu, Rose Ebelle, Nadya Lukacher, Steven E. Pincus, Xun Chen, James P. Porter, Roger Zabinski, Linda L. Nardone, Lisa Duncan, Wu Peng, Muctarr Sesay, George L. Spitalny, Juan Li, Nehal Mohamed, Leslie S. Casey
Publikováno v:
Clinical Immunology. 105:141-154
Autoantibodies that react with double-stranded DNA (dsDNA) are a hallmark for diagnosis of systemic lupus erythematosus (SLE) and are also considered the pathogenic subset that is most associated with lupus nephritis. As an agent to remove the pathog
Autor:
Ellen P. Carmichael, George L. Spitalny, Robert Plourde, Michael F. Ernst, Mark A. Findeis, Brett S. Robinson, June R. Merwin, Joanne L. Suchoski
Publikováno v:
Drug Delivery. 2:136-143
Receptor-mediated targeting to the liver using galactose-terminated ligands is a promising strategy for site-specific delivery of antiviral drugs for treatment of hepatitis B virus infection. Optimization of drug conjugates for receptor-mediated deli
Publikováno v:
ISGT Europe
The increasing number of Distributed Generation Units (DGs) in distribution grids is challenging the way electrical systems are designed and operated. For traditional power systems, Low Voltage (LV) networks play a passive role in voltage regulation,
Autor:
Wendy L. Thomas, G. Stephen Noell, Mark A. Findeis, June R. Merwin, Henry C. Chiou, George L. Spitalny, Timothy D. McKee, Mary E. DeRome
Publikováno v:
Bioconjugate Chemistry. 5:612-620
In vivo gene therapy shows promise as a treatment for both genetic and acquired disorders. The hepatic asialoglycoprotein receptor (ASGPr) binds asialoorosomucoid-polylysine-DNA (ASOR-PL-DNA) complexes and allows targeted delivery to hepatocytes. The