Zobrazeno 1 - 10
of 34
pro vyhledávání: '"L, Sekut"'
Autor:
Stephen A. Stimpson, R H Brown, J A Wakefield, Brian Edward Marron, James G. Conway, J J Jeffreys, L Sekut, R L Clark, J. A. Menius, A McElroy
Publikováno v:
The Journal of Experimental Medicine
Considerable evidence has associated the expression of matrix metalloproteinases (MMPs) with the degradation of cartilage and bone in chronic conditions such as arthritis. Direct evaluation of MMPs' role in vivo has awaited the development of MMP inh
Autor:
T J, Parry, T A, Riccobene, S J, Strawn, R, Williams, R, Daoud, J, Carrell, S, Sosnovtseva, R C, Miceli, C M, Poortman, L, Sekut, Y, Li, J, Fikes, C, Sung
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 296(2)
B lymphocyte stimulator (BLyS; also known as TNFSF20, BAFF, TALL-1, zTNF4, and THANK), a tumor necrosis factor ligand family member, has recently been identified as a factor that promotes expansion and differentiation of the B cell population, leadin
Autor:
Margaret Hugunin, Robert V. Talanian, L. Sekut, H. Allen, A. Carter, Michael Paskind, T. Ghayur, Daniel E. Tracey, D. Butler, S. Banerjee, Winnie W. Wong, Linda Herzog, L. Quintal, Robert Kamen
Publikováno v:
Nature. 386(6625)
Interferon-gamma-inducing factor (IGIF, interleukin-18) is a recently described cytokine that shares structural features with the interleukin-1 (IL-1) family of proteins and functional properties with IL-12. Like IL-12, IGIF is a potent inducer of in
Autor:
L, Sekut, B, Han, P, Baer, M W, Verghese, R, Silverstein, L, Clifton, S, Dennis, M J, Numerick, K M, Connolly
Publikováno v:
Laboratory animal science. 45(6)
Using tumor necrosis factor (TNF) inhibition in dog blood as a measure of efficacy, and canine emesis as a measure of toxicity, we were able to assign a therapeutic index to rolipram, a prototypic anti-inflammatory compound. Because both assays were
SUMMARY Elevation of intracellular cAMP levels has been shown previously to inhibit cytokine secretion by various cell types in vitro. Since salmeterol is a β2-agonist which activates adenylate cyclase, its ability to inhibit cytokine production was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6346319987433d05566e15dcd43ec88
https://europepmc.org/articles/PMC1534196/
https://europepmc.org/articles/PMC1534196/
Autor:
J. A. Menius, L. S. Noel, D P Yarnall, L. Sekut, K M Connolly, M. F. Brackeen, R. L. Clark, Stephen A. Stimpson, R. Bateman-Fite
SUMMARY Inhibitors of cyclic nucleotide phosphodiesterases are known to suppress lipopolysaccharide (LPS)-induced tumour necrosis factor-alpha (TNF-α) production in vitro in human monocytes. The most potent of these have selectivity for type IV PDEs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3dc2c3ef7a792cac994fadbfa7e1f0
Publikováno v:
The Journal of laboratory and clinical medicine. 124(6)
Elevated tumor necrosis factor (TNF) levels have been reported in various models of acute and chronic inflammation and used by many investigators to determine the stage of disease and effectiveness of treatment. Because of the documented involvement
Autor:
L. Quintal, Robert V. Talanian, Winnie W. Wong, Linda Herzog, A. Carter, L. Sekut, Daniel E. Tracey, Margaret Hugunin, H. Allen, S. Banerjee, D. Butler, Robert Kamen, T. Ghayur
Publikováno v:
Shock. 7:84
Autor:
J, Parry T, A, Riccobene T, J, Strawn S, R, Williams, R, Daoud, J, Carrell, S, Sosnovtseva, C, Miceli R, M, Poortman C, L, Sekut, Y, Li, J, Fikes, C, Sung
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; February 2001, Vol. 296 Issue: 2 p396-404, 9p
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