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Autor:
B. Baroukh, J. L. Saffar
Publikováno v:
Mediators of Inflammation, Vol 1, Iss 5, Pp 335-339 (1992)
The effects of leukotriene (LT) inhibition on gingival and adjacent bone compartments were assessed by using phenidone (100 mg/kg/d) and ketoconazole (50 mg/kg/d) given for 4 weeks to periodontitis-affected hamsters. In the gingiva the two agents sig
Externí odkaz:
https://doaj.org/article/559309170eee46d1bb95836a6c19e3f1
Autor:
Antonia Terriza, Anni Llorens, Antonio Batista, Daniel Torres-Lagares, Raquel Castillo-Oyagüe, Rocío Velázquez Cayón, Brigitte Barouk, Jose L. Gutierrez-Perez, Jean L. Saffar, Gabriel Castillo-Dalí, Javier Cabezas-Talavero, Angel Barranco, Christopher D. Lynch, Alastair James Sloan
Publikováno v:
Journal of dentistry. 42(11)
Objectives: To evaluate the bone regeneration potential of a new membrane fabricated with polyglycolide acid (PLGA) after being treated with oxygen plasma (PO2), and/or being functionalized with silicon dioxide (SiO2) or titanium dioxide (TiO2) nanop
Autor:
J. J. Lasfargues, J. L. Saffar
Publikováno v:
The Anatomical Record. 234:310-316
Little is known about local bone regulation that enables spontaneous molar tooth drift. In this study the role of prostaglandins (PGs) were investigated in the rat by inhibiting PG-synthesis with indomethacin (7 mg/kg/d). Untreated animals were kille
Autor:
A. Garcia, J. L. Saffar
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 17:211-216
The aim of this experiment was to study endosteal bone reactions around roots transplanted into an edentulous crest, and the role, if any, of periodontal ligament (PDL) remnants preservation. After extraction of pre-molars and healing of the crests,
Publikováno v:
Experimental physiology. 91(3)
Short-term studies have shown that histamine is involved, via its H2 receptors (H2R), in the mediator network regulating trabecular bone loss in long bones of ovariectomized (OVX) rats. It is not known whether this effect of histamine persists over t
Publikováno v:
Anticancer research. 19(3A)
Sodium phenylacetate (NaPa), a physiological product of phenylalanine metabolism, present in micromolar concentrations in human plasma, has been shown to induce in vivo and in vitro cytostatic antiproliferative effects at millimolar concentrations. C
Publikováno v:
Cells, tissues, organs. 164(3)
RGTA, a new family of dextran-derived healing agents, promotes the repair of various tissues, including bone. In this study, we examined whether a dose of RGTA lower than in our previous studies could still modify the healing pattern in craniotomy de
Autor:
C, Dobigny, J L, Saffar
Publikováno v:
Journal of cellular physiology. 173(1)
We have previously postulated that mast cells (MC) may act as accessory cells in bone resorption. In this study we obtained evidence that histamine, the most abundant mediator released upon MC degranulation, is one of many factors modulating resorpti
Autor:
M, Klapisz-Wolikow, J L, Saffar
Publikováno v:
Journal of cellular physiology. 167(2)
In addition to their antibacterial effects, tetracyclines may inhibit interstitial collagenase activity and bone resorption. These properties were assessed morphometrically using minocycline (25 and 50 mg/kg/day given by the IM route) in a rat model